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Over the past few years, microRNAs (miRNAs) have emerged as a new prominent class of gene regulatory factors that negatively regulate expression of approximately one-third of the genes in animal genomes at post-transcriptional level.…

Genomics · Quantitative Biology 2007-05-23 Qinghua Cui , Zhenbao Yu , Youlian Pan , Enrico Purisima , Edwin Wang

The growing demand for sustainable development brings a series of information technologies to help agriculture production. Especially, the emergence of machine learning applications, a branch of artificial intelligence, has shown multiple…

Computer Vision and Pattern Recognition · Computer Science 2023-10-20 Jianping Yao , Son N. Tran , Samantha Sawyer , Saurabh Garg

In biological research machine learning algorithms are part of nearly every analytical process. They are used to identify new insights into biological phenomena, interpret data, provide molecular diagnosis for diseases and develop…

Microbial identification is a central issue in microbiology, in particular in the fields of infectious diseases diagnosis and industrial quality control. The concept of species is tightly linked to the concept of biological and clinical…

Machine Learning · Statistics 2015-06-25 Kévin Vervier , Pierre Mahé , Jean-Baptiste Veyrieras , Jean-Philippe Vert

Circular RNAs (circRNAs) are important components of the non-coding RNA regulatory network. Previous circRNA identification primarily relies on high-throughput RNA sequencing (RNA-seq) data combined with alignment-based algorithms that…

Machine Learning · Computer Science 2025-07-14 Tianyou Jiang

Inclusion of high throughput technologies in the field of biology has generated massive amounts of biological data in the recent years. Now, transforming these huge volumes of data into knowledge is the primary challenge in computational…

Machine Learning · Computer Science 2021-12-06 Dibyendu Ghosh , Srija Chakraborty , Hariprasad Kodamana , Supriya Chakraborty

Plant phenotyping (Guo et al. 2021; Pieruschka et al. 2019) focuses on studying the diverse traits of plants related to the plants' growth. To be more specific, by accurately measuring the plant's anatomical, ontogenetical, physiological…

Machine Learning · Computer Science 2022-01-17 Jun Wu , Elizabeth A. Ainsworth , Sheng Wang , Kaiyu Guan , Jingrui He

Single-cell RNA sequencing (scRNA-seq) has revolutionized our ability to analyze gene expression at the resolution of individual cells, providing unprecedented insights into cellular heterogeneity and complex biological systems. This paper…

Other Quantitative Biology · Quantitative Biology 2024-06-11 Megha Patel , Nimish Magre , Himanshi Motwani , Nik Bear Brown

MicroRNAs (miRNAs) are small non-coding RNAs that function as regulators of gene expression. In recent years, there has been a tremendous and growing interest among researchers to investigate the role of miRNAs in normal cellular as well as…

Applications · Statistics 2018-04-13 Noirrit Kiran Chandra , Richa Singh , Sourabh Bhattacharya

MicroRNAs (miRNAs) are small RNA molecules, about 22 nucleotide long, which post-transcriptionally regulate their target messenger RNAs (mRNAs). They accomplish key roles in gene regulatory networks, ranging from signaling pathways to…

Molecular Networks · Quantitative Biology 2012-10-09 Carla Bosia , Andrea Pagnani , Riccardo Zecchina

MicroRNAs (miRNAs) are small endogenous regulatory molecules that modulate gene expression post-transcriptionally. Although differential expression of miRNAs have been implicated in many diseases (including cancers), the underlying…

Genomics · Quantitative Biology 2018-01-09 Gary Wilk , Rosemary Braun

Designing RNA molecules has garnered recent interest in medicine, synthetic biology, biotechnology and bioinformatics since many functional RNA molecules were shown to be involved in regulatory processes for transcription, epigenetics and…

Machine Learning · Computer Science 2019-04-15 Frederic Runge , Danny Stoll , Stefan Falkner , Frank Hutter

Computational analysis methods including machine learning have a significant impact in the fields of genomics and medicine. High-throughput gene expression analysis methods such as microarray technology and RNA sequencing produce enormous…

Genomics · Quantitative Biology 2022-09-28 Nikita Bhandari , Rahee Walambe , Ketan Kotecha , Satyajeet Khare

Data is crucial for machine learning (ML) applications, yet acquiring large datasets can be costly and time-consuming, especially in complex, resource-intensive fields like biopharmaceuticals. A key process in this industry is upstream…

Machine Learning · Computer Science 2025-06-23 Johnny Peng , Thanh Tung Khuat , Katarzyna Musial , Bogdan Gabrys

Plant diseases are considered one of the main factors influencing food production and minimize losses in production, and it is essential that crop diseases have fast detection and recognition. The recent expansion of deep learning methods…

Computer Vision and Pattern Recognition · Computer Science 2020-09-10 Andre S. Abade , Paulo Afonso Ferreira , Flavio de Barros Vidal

MicroRNAs (miRNAs) are endogenous 22-nucleotide RNAs, which suppress gene expression by selectively binding to the 3-noncoding region of specific message RNAs through base-pairing. Given the diversity and abundance of miRNA targets, miRNAs…

Molecular Networks · Quantitative Biology 2007-05-23 Qinghua Cui , Zhenbao Yu , Enrico O. Purisima , Edwin Wang

Microarray is one of the essential technologies used by the biologist to measure genome-wide expression levels of genes in a particular organism under some particular conditions or stimuli. As microarrays technologies have become more…

Artificial Intelligence · Computer Science 2020-05-05 Khalid Raza

RNA is a fundamental class of biomolecules that mediate a large variety of molecular processes within the cell. Computational algorithms can be of great help in the understanding of RNA structure-function relationship. One of the main…

Biomolecules · Quantitative Biology 2015-02-20 Sandro Bottaro , Francesco Di Palma , Giovanni Bussi

A novel group of small non-coding RNA, known as microRNA (miRNA) is predicted to regulate as high as 90% of the coding genes in human. The diversity and abundance of miRNA targets offer an enormous level of combinatorial possibilities and…

Genomics · Quantitative Biology 2010-09-03 Sushmita Mookherjee , Mithun Sinha , Saikat Mukhopadhyay , Nitai P. Bhattacharyya , P. K. Mohanty

Process mining enables the reconstruction and evaluation of business processes based on digital traces in IT systems. An increasingly important technique in this context is process prediction. Given a sequence of events of an ongoing trace,…

Machine Learning · Computer Science 2021-06-09 Dominic A. Neu , Johannes Lahann , Peter Fettke