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The main aim of this study is to analyze a fractional parabolic SIR epidemic model of a reaction-diffusion, by using the nonlocal Caputo fractional time-fractional derivative and employing the $p$-Laplacian operator. The immunity is imposed…

Optimization and Control · Mathematics 2025-04-25 Achraf Zinihi , Moulay Rchid Sidi Ammi , Delfim F. M. Torres

In this work we study a fractional SEIR biological model of a reaction-diffusion, using the non-singular kernel Caputo-Fabrizio fractional derivative in the Caputo sense and employing the Laplacian operator. In our PDE model, the government…

Dynamical Systems · Mathematics 2025-05-13 Achraf Zinihi , Moulay Rchid Sidi Ammi , Matthias Ehrhardt

In this paper, we consider an optimal distributed control problem for a reaction-diffusion-based SIR epidemic model with human behavioral effects. We develop a model wherein non-pharmaceutical intervention methods are implemented, but a…

Analysis of PDEs · Mathematics 2025-02-11 Marcelo Bongarti , Christian Parkinson , Weinan Wang

We investigate the celebrated mathematical SICA model but using fractional differential equations in order to better describe the dynamics of HIV-AIDS infection. The infection process is modelled by a general functional response and the…

Optimization and Control · Mathematics 2021-01-21 Adnane Boukhouima , El Mehdi Lotfi , Marouane Mahrouf , Silverio Rosa , Delfim F. M. Torres , Noura Yousfi

A Caputo fractional-order mathematical model for the transmission dynamics of tuberculosis (TB) was recently proposed in [Math. Model. Nat. Phenom. 13 (2018), no. 1, Art. 9]. Here, a sensitivity analysis of that model is done, showing the…

Optimization and Control · Mathematics 2019-08-12 Silverio Rosa , Delfim F. M. Torres

Distributed-order fractional non-local operators have been introduced and studied by Caputo at the end of the 20th century. They generalize fractional order derivatives/integrals in the sense that such operators are defined by a weighted…

Optimization and Control · Mathematics 2020-10-27 Faical Ndairou , Delfim F. M. Torres

A human respiratory syncytial virus surveillance system was implemented in Florida in 1999, to support clinical decision-making for prophylaxis of premature newborns. Recently, a local periodic SEIRS mathematical model was proposed in…

Optimization and Control · Mathematics 2018-10-25 Silverio Rosa , Delfim F. M. Torres

This paper is concerned with the well-posedness and optimal control problem of a reaction-diffusion system for an epidemic Susceptible-Infected-Recovered-Susceptible (SIRS) mathematical model in which the dynamics develops in a spatially…

Optimization and Control · Mathematics 2023-04-24 Pierluigi Colli , Gianni Gilardi , Gabriela Marinoschi , Elisabetta Rocca

This paper investigates a behavioral-feedback SIR model in which the infection rate adapts dynamically based on the fractions of susceptible and infected individuals. We introduce an invariant of motion and we characterize the peak of…

Populations and Evolution · Quantitative Biology 2025-09-17 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

Over the past several decades there has been a proliferation of epidemiological models with ordinary derivatives replaced by fractional derivatives in an an-hoc manner. These models may be mathematically interesting but their relevance is…

Populations and Evolution · Quantitative Biology 2016-03-31 C. N. Angstmann , B. I. Henry , A. V. McGann

We consider a behavioral-feedback SIR epidemic model, in which the infection rate depends in feedback on the fractions of susceptible and infected agents, respectively. The considered model allows one to account for endogenous adaptation…

Systems and Control · Electrical Eng. & Systems 2026-02-11 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

This article presents the solution of the fractional SIR epidemic model using the Laplace residual power series method. We introduce the fractional SIR model in the sense of Caputo's derivative, it is presented by three fractional…

Quantitative Methods · Quantitative Biology 2023-06-21 Ahmad Qazza , Rania Saadeh

In this paper, an SIR epidemic model with variable size of population is considered. We study optimal control problem for an SIR model with "vaccination" and "treatment" as controls. It is shown that an optimal control exists. We have…

Optimization and Control · Mathematics 2016-12-28 Olga Klimenkova

We consider an optimal control problem for a dynamical system described by a Caputo fractional differential equation and a terminal cost functional. We prove that, under certain assumptions, the (non-smooth, in general) value functional of…

Optimization and Control · Mathematics 2024-04-25 Mikhail Gomoyunov

This paper analyses the optimal control of infectious disease propagation using a classic susceptible-infected-recovered (SIR) model characterised by permanent immunity and the absence of available vaccines. The control is performed over a…

Optimization and Control · Mathematics 2024-06-12 Rocío Balderrama , Mariana Inés Prieto , Constanza Sánchez de la Vega , Federico Vazquez

We propose and study an optimal control model for malaria infection described by system of fractional differential equations. The model is formulated in terms of the left and right Caputo fractional derivatives. We determine the necessary…

Dynamical Systems · Mathematics 2016-07-07 E. Okyere , F. T. Oduro , S. K. Amponsah , I. K. Dontwi

We present a method to solve fractional optimal control problems, where the dynamic depends on integer and Caputo fractional derivatives. Our approach consists to approximate the initial fractional order problem with a new one that involves…

Optimization and Control · Mathematics 2016-10-25 Ricardo Almeida , Delfim F. M. Torres

Epidemiological modeling is vital in understanding disease dynamics and guiding public health interventions. This study presents a time-fractional SEIR model to describe the transmission dynamics of Mpox, incorporating memory effects via…

Numerical Analysis · Mathematics 2026-01-29 Gaurav Saini , Bappa Ghosh , Sunita Chand , Jugal Mohapatra

In this research paper, we examine an optimal control problem involving a dynamical system governed by a nonlinear Caputo fractional time-delay state equation. The primary objective of this study is to obtain the necessary conditions for…

Optimization and Control · Mathematics 2024-01-31 Jasarat J. Gasimov , Nazim I. Mahmudov

Research focus on optimal control problems brought on by fractional differential equations has been extensively applied in practice. However, because they are still open-ended and challenging, a number of problems with fractional…

Populations and Evolution · Quantitative Biology 2023-04-25 Samuel Okyere , Joseph Ackora-Prah , Kwaku Forkuoh Darkwah , Francis Tabi Oduro , Ebenezer Bonyah
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