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High-throughput sequencing has transformed microbiome research, but it also produces inherently compositional data that challenge standard statistical and machine learning methods. In this work, we propose a multinomial classification…

Applications · Statistics 2025-12-23 R. Alberich , N. A. Cruz , R. Fernández , I. García Mosquera , A. Mir , F. Rosselló

Dealing with missing data poses significant challenges in predictive analysis, often leading to biased conclusions when oversimplified assumptions about the missing data process are made. In cases where the data are missing not at random…

Methodology · Statistics 2024-12-20 Yong Chen Goh , Wuu Kuang Soh , Andrew C. Parnell , Keefe Murphy

In this paper, we introduce the first machine learning framework for predicting optimal processing times in Single-Level Tree Network (SLTN) architectures for the Divisible Load Theory (DLT) paradigm. Using a feedforward neural network(FNN)…

Machine Learning · Computer Science 2026-05-25 Bharadwaj Veeravalli

This paper proposes a novel meta-learning approach to optimize a robust portfolio ensemble. The method uses a deep generative model to generate diverse and high-quality sub-portfolios combined to form the ensemble portfolio. The generative…

Neural and Evolutionary Computing · Computer Science 2023-07-18 Kamer Ali Yuksel

While covariance matrices have been widely studied in many scientific fields, relatively limited progress has been made on estimating conditional covariances that permits a large covariance matrix to vary with high-dimensional subject-level…

Methodology · Statistics 2025-05-28 Rakheon Kim , Jingfei Zhang

Monitoring cavity-nesting wild bees and wasps is vital for biodiversity research and conservation. Layer trap nests (LTNs) are emerging as a valuable tool to study the abundance and species richness of these insects, offering insights into…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Chenchang Liu , Felix Fornoff , Annika Grasreiner , Patrick Maeder , Henri Greil , Marco Seeland

Several classification methods assume that the underlying distributions follow tree-structured graphical models. Indeed, trees capture statistical dependencies between pairs of variables, which may be crucial to attain low classification…

Machine Learning · Statistics 2021-05-31 Yaniv Tenzer , Amit Moscovich , Mary Frances Dorn , Boaz Nadler , Clifford Spiegelman

Neural circuits contain heterogeneous groups of neurons that differ in type, location, connectivity, and basic response properties. However, traditional methods for dimensionality reduction and clustering are ill-suited to recovering the…

Machine Learning · Statistics 2016-10-27 Scott W. Linderman , Ryan P. Adams , Jonathan W. Pillow

Empirical networks are often globally sparse, with a small average number of connections per node, when compared to the total size of the network. However, this sparsity tends not to be homogeneous, and networks can also be locally dense,…

Physics and Society · Physics 2020-07-20 Tiago P. Peixoto

Multivariate categorical data occur in many applications of machine learning. One of the main difficulties with these vectors of categorical variables is sparsity. The number of possible observations grows exponentially with vector length,…

Machine Learning · Statistics 2015-03-10 Yarin Gal , Yutian Chen , Zoubin Ghahramani

Real-world time series often exhibit strong non-stationarity, complex nonlinear dynamics, and behavior expressed across multiple temporal scales, from rapid local fluctuations to slow-evolving long-range trends. However, many contemporary…

Machine Learning · Computer Science 2026-05-19 Sumit S Shevtekar , Chandresh K Maurya

Decision trees are a popular family of models due to their attractive properties such as interpretability and ability to handle heterogeneous data. Concurrently, missing data is a prevalent occurrence that hinders performance of machine…

Machine Learning · Computer Science 2020-07-01 Pasha Khosravi , Antonio Vergari , YooJung Choi , Yitao Liang , Guy Van den Broeck

The ongoing explosion of genome sequence data is transforming how we reconstruct and understand the histories of biological systems. Across biological scales, from individual cells to populations and species, trees-based models provide a…

Populations and Evolution · Quantitative Biology 2025-12-08 Yun Deng , Shing H. Zhan , Yulin Zhang , Chao Zhang , Bingjie Chen

When choosing a suitable technique for regression and classification with multivariate predictor variables, one is often faced with a tradeoff between interpretability and high predictive accuracy. To give a classical example,…

Machine Learning · Statistics 2011-01-10 Nicolai Meinshausen

A promising class of generative models maps points from a simple distribution to a complex distribution through an invertible neural network. Likelihood-based training of these models requires restricting their architectures to allow cheap…

Machine Learning · Computer Science 2018-10-23 Will Grathwohl , Ricky T. Q. Chen , Jesse Bettencourt , Ilya Sutskever , David Duvenaud

In phylogenomics, species-tree methods must contend with two major sources of noise; stochastic gene-tree variation under the multispecies coalescent model (MSC) and finite-sequence substitutional noise. Fast agglomerative methods such as…

Populations and Evolution · Quantitative Biology 2025-07-11 Georgios Aliatimis , Ruriko Yoshida , Burak Boyaci , James A. Grant

We propose a generative model for robust tensor factorization in the presence of both missing data and outliers. The objective is to explicitly infer the underlying low-CP-rank tensor capturing the global information and a sparse tensor…

Computer Vision and Pattern Recognition · Computer Science 2016-06-21 Qibin Zhao , Guoxu Zhou , Liqing Zhang , Andrzej Cichocki , Shun-ichi Amari

Big data applications, such as medical imaging and genetics, typically generate datasets that consist of few observations n on many more variables p, a scenario that we denote as p>>n. Traditional data processing methods are often…

Data Analysis, Statistics and Probability · Physics 2016-05-18 Magnus O. Ulfarsson , Frosti Palsson , Jakob Sigurdsson , Johannes R. Sveinsson

The human microbiome plays an important role in human health and disease status. Next generating sequencing technologies allow for quantifying the composition of the human microbiome. Clustering these microbiome data can provide valuable…

Methodology · Statistics 2021-01-07 Wangshu Tu , Sanjeena Subedi

Statistical analysis of microbiome data is challenging. Bayesian multinomial logistic-normal (MLN) models have gained popularity due to their ability to account for the count compositional nature of these data, but existing approaches are…

Methodology · Statistics 2025-05-27 Tinghua Chen , Michelle Pistner Nixon , Justin D. Silverman