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Mathematical and computational modeling approaches are increasingly used as quantitative tools in the analysis and forecasting of infectious disease epidemics. The growing need for realism in addressing complex public health questions is…
Two of the principle tasks of causal inference are to define and estimate the effect of a treatment on an outcome of interest. Formally, such treatment effects are defined as a possibly functional summary of the data generating…
We present a deterministic mathematical model for malaria transmission with waning immunity. The model consists of five non-linear system of differential equations. We used next generation matrix to derive the basic reproduction number…
Despite substantial advances in global measles vaccination, measles disease burden remains high in many low- and middle-income countries. A key public health strategy for controling measles in such high-burden settings is to conduct…
Analyses of cluster randomized trials (CRTs) can be complicated by informative missing outcome data. Methods such as inverse probability weighted generalized estimating equations have been proposed to account for informative missingness by…
The organization and mining of malaria genomic and post-genomic data is highly motivated by the necessity to predict and characterize new biological targets and new drugs. Biological targets are sought in a biological space designed from…
Models for dependent data are distinguished by their targets of inference. Marginal models are useful when interest lies in quantifying associations averaged across a population of clusters. When the functional form of a covariate-outcome…
Chronic diseases are long-lasting conditions that require lifelong medical attention. Using big EMR data, we have developed early disease risk prediction models for five common chronic diseases: diabetes, hypertension, CKD, COPD, and…
BACKGROUND There is an increasing demand for high quality subnational estimates of under-five mortality. In low and middle income countries, where the burden of under-five mortality is concentrated, vital registration is often lacking and…
We consider a causal inference model in which individuals interact in a social network and they may not comply with the assigned treatments. In particular, we suppose that the form of network interference is unknown to researchers. To…
Improving health in the most disadvantaged populations requires reliable estimates of health and demographic indicators to inform policy and interventions. Low- and middle-income countries with the largest burden of disease and disability…
Cancer is a significant health issue globally and it is well known that cancer risk varies geographically. However in many countries there are no small area level data on cancer risk factors with high resolution and complete reach, which…
Malaria, which primarily spreads with the bite of female anopheles mosquitos, often leads to death of people - specifically children in the age-group of 0-5 years. Clinical experts identify malaria by observing RBCs in blood smeared images…
Accurate estimates of the under-5 mortality rate (U5MR) in a developing world context are a key barometer of the health of a nation. This paper describes new models to analyze survey data on mortality in this context. We are interested in…
Measles is considered as a highly contagious disease that leads to serious complications around the world. Thus, the paper determined the trend and the five-year forecasted data of the Measles in the Philippines. This study utilized the…
In this study, we propose an automatic learning method for variables selection based on Lasso in epidemiology context. One of the aim of this approach is to overcome the pretreatment of experts in medicine and epidemiology on collected…
The Joint United Nations Programme on HIV/AIDS (UNAIDS) has developed the Estimation and Projection Package (EPP) for making national estimates and short-term projections of HIV prevalence based on observed prevalence trends at antenatal…
Although interventional studies demonstrate that preventing malaria during pregnancy can reduce the low birth weight (i.e., child's birth weight $<$ 2,500 grams) rate, it remains unknown whether natural changes in parasite transmission and…
As developing countries continue to face challenges associated with infectious diseases, the need to improve infrastructure to systematically collect data which can be used to understand their outbreak patterns becomes more critical. The…
Infectious disease is a leading threat to public health, economic stability, and other key social structures. Efforts to mitigate these impacts depend on accurate and timely monitoring to measure the risk and progress of disease.…