Related papers: Photoacoustic Silk Scaffolds for Neural stimulatio…
We report on a novel dual-structure scaffold fabricated using two-photon polymerisation (2PP), integrating electrically conductive and non-conductive regions within a single architecture, targeting neural tissue regeneration. Poly(ethylene…
Unlike other tissue types, the nervous tissue extends to a wide and complex environment that provides a plurality of different biochemical and topological stimuli which in turn define the functions of that tissue. As a consequence of such…
Silicon-substituted hydroxyapatite (SiHA) macroporous scaffolds have been prepared by robocasting. In order to optimize their bone regeneration properties, we have manufactured these scaffolds presenting different microstructures:…
Neural tissue engineering holds incredible potential to restore functional capabilities to damaged neural tissue. It was hypothesized that patterned and functionalized nanofiber scaffolds could control neurite direction and enhance neurite…
Photonic technologies offer great prospects for novel ultrafast, energy-efficient and hardware-friendly neuromorphic (brain-like) computing platforms. Moreover, neuromorphic photonic approaches based upon ubiquitous, technology-mature and…
The spontaneous activity pattern of cortical neurons in dissociated culture is characterized by burst firing that is highly synchronized among a wide population of cells. The degree of synchrony, however, is excessively higher than that in…
Computational hardware designed to mimic biological neural networks holds the promise to resolve the drastically growing global energy demand of artificial intelligence. A wide variety of hardware concepts have been proposed, and among…
Macroporous scaffolds made of a SiO2-CaO-P2O5 mesoporous bioactive glass (MBG) and epolycaprolactone (PCL) have been prepared by robocasting. These scaffolds showed an excellent in vitro biocompatibility in contact with osteoblast like…
Achieving an optimal biomechanical environment within bone scaffolds is critical for promoting tissue regeneration, particularly in load-bearing anatomical sites where rigid fixation can induce stress shielding and compromise healing.…
Cell-free translational strategies are needed to accelerate the repair of mineralised tissues, particularly large bone defects, using minimally invasive approaches. Regenerative bone scaffolds should ideally mimic aspects of the tissue's…
Developing successful scaffolds requires clinicians to adopt a multidisciplinary approach in order to understand and stimulate the natural bone regeneration process. A variety of natural and synthetic biomaterials, including naturally…
Biomaterials are becoming an essential tool in the study and application of stem cell research. Various types of biomaterials enable three-dimensional (3D) culture of stem cells, and, more recently, also enable high-resolution patterning…
Ensuring energy-efficient design in neuromorphic computing systems necessitates a tailored architecture combined with algorithmic approaches. This manuscript focuses on enhancing brain-inspired perceptual computing machines through a novel…
Spiking neural networks are neuromorphic systems that emulate certain aspects of biological neurons, offering potential advantages in energy efficiency and speed by for example leveraging sparsity. While CMOS-based electronic SNN hardware…
Plastic self-adaptation, nonlinear recurrent dynamics and multi-scale memory are desired features in hardware implementations of neural networks, because they enable them to learn, adapt and process information similarly to the way…
Starch based scaffolds are considered as promising biomaterials for bone tissue engineering. In this study, a highly porous starch/polyvinyl alcohol (PVA) based nanocomposite scaffold with a gradient pore structure was made by incorporating…
Neuromorphic computing seeks to replicate the spiking dynamics of biological neurons for brain-inspired computation. While electronic implementations of artificial spiking neurons have dominated to date, photonic approaches are attracting…
Neuromorphic computing-modelled after the functionality and efficiency of biological neural systems-offers promising new directions for advancing artificial intelligence and computational models. Photonic techniques for neuromorphic…
A hallmark of biological intelligence is neural reuse,the ability to preserve past learning and repurpose it for new tasks and changing environments. Photonic neural hardware offers high-bandwidth, low-latency computation, but current…
Scaffolds have a key role in the clinical success of tissue engineering for the regeneration of damaged tissues. Their bio-performance is often described as the extent to which they can provide an extracellular matrix-like environment for…