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The assessment of safety is an important aspect of the evaluation of new therapies in clinical trials, with analyses of adverse events being an essential part of this. Standard methods for the analysis of adverse events such as the…
Quantifying the heterogeneity is an important issue in meta-analysis, and among the existing measures, the $I^2$ statistic is most commonly used. In this paper, we first illustrate with a simple example that the $I^2$ statistic is heavily…
Psychological support hotlines are an effective suicide prevention measure that typically relies on professionals using suicide risk assessment scales to predict individual risk scores. However, the accuracy of scale-based predictive…
The ability to recognize weakness of students and solving any problem may confront them in timely fashion is always a target of all educational institutions. This study was designed to explore how can predictive and statistical analysis…
Quantifying the heterogeneity is an important issue in meta-analysis, and among the existing measures, the $I^2$ statistic is the most commonly used measure in the literature. In this paper, we show that the $I^2$ statistic was, in fact,…
There has been a significant increase in the development of data-driven safety analytics approaches in recent years. In light of these advances it has become imperative to evaluate such approaches in a principled way to determine their…
We introduce a statistical agent based model to describe the phenomenon of drug abuse and its dynamical evolution at the individual and global level. The agents are heterogeneous with respect to their intrinsic inclination to drugs, to…
This paper is about how we study statistical methods. As an example, it uses the random regressions model, in which the intercept and slope of cluster-specific regression lines are modeled as a bivariate random effect. Maximizing this…
We investigate the statistical methods applied throughout safety analysis of complex systems. The tolerance interval method implemented in the widely utilized 0.95|0.95 methodology is analyzed. We point out a remarkable weakness of the…
Random-effects models are frequently used to synthesise information from different studies in meta-analysis. While likelihood-based inference is attractive both in terms of limiting properties and of implementation, its application in…
There is a great concern nowadays regarding alcohol consumption and drug abuse, especially in young people. Analyzing the social environment where these adolescents are immersed, as well as a series of measures determining the alcohol abuse…
Background: Many researchers have studied the relationship between diet and health. There are papers showing an association between the consumption of sugar-sweetened beverages and Type 2 diabetes. Many meta-analyses use individual studies…
In the light of increasing clues on social media impact on self-harm and suicide risks, there is still no evidence on who are and how factually engaged in suicide-related online behaviors. This study reports new findings of high-performance…
Data analysis is a powerful tool in all experimental sciences. Statistical methods, such as sampling theory, computer technologies necessary for handling large amounts of data, skill in analysing information contained in different types of…
This paper extends my research applying statistical decision theory to treatment choice with sample data, using maximum regret to evaluate the performance of treatment rules. The specific new contribution is to study as-if optimization…
Increasing integration and availability of data on large groups of persons has been accompanied by proliferation of statistical and other algorithmic prediction tools in banking, insurance, marketiNg, medicine, and other FIelds (see e.g.,…
Using social media data for statistical analysis of general population faces commonly two basic obstacles: firstly, social media data are collected for different objects than the population units of interest; secondly, the relevant measures…
Individualized treatment decisions can improve health outcomes, but using data to make these decisions in a reliable, precise, and generalizable way is challenging with a single dataset. Leveraging multiple randomized controlled trials…
Large technology firms face the problem of moderating content on their online platforms for compliance with laws and policies. To accomplish this at the scale of billions of pieces of content per day, a combination of human and machine…
There is increasing interest in combining information from experimental studies, including randomized and single-group trials, with information from external experimental or observational data sources. Such efforts are usually motivated by…