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Algorithms for laying out large graphs have seen significant progress in the past decade. However, browsing large graphs remains a challenge. Rendering thousands of graphical elements at once often results in a cluttered image, and…

Biogeographical regions (bioregions) reveal how different sets of species are spatially grouped and therefore are important units for conservation, historical biogeography, ecology and evolution. Several methods have been developed to…

Quantitative Methods · Quantitative Biology 2016-12-01 Daniel Edler , Thaís Guedes , Alexander Zizka , Martin Rosvall , Alexandre Antonelli

Biologists are leading current research on genome characterization (sequencing, alignment, transcription), providing a huge quantity of raw data about many genome organisms. Extracting knowledge from this raw data is an important process…

Quantitative Methods · Quantitative Biology 2007-05-23 Nicolas Férey , Pierre-Emmanuel Gros , Joan Hérisson , Rachid Gherbi

Unsupervised data representation and visualization using tools from topology is an active and growing field of Topological Data Analysis (TDA) and data science. Its most prominent line of work is based on the so-called Mapper graph, which…

Machine Learning · Computer Science 2025-06-04 Ziyad Oulhaj , Mathieu Carrière , Bertrand Michel

Interpretability is becoming an active research topic as machine learning (ML) models are more widely used to make critical decisions. Tabular data is one of the most commonly used modes of data in diverse applications such as healthcare…

Machine Learning · Statistics 2021-12-01 Amirata Ghorbani , Dina Berenbaum , Maor Ivgi , Yuval Dafna , James Zou

The rapid development of tools for acquisition and storage of information has lead to the formation of enormous medical databases. The large quantity of data definitely surpasses the abilities of humans for efficient usage without…

Information Retrieval · Computer Science 2009-04-03 Petar Kormushev

Motivation: The Mapper algorithm is an essential tool to explore shape of data in topology data analysis. With a dataset as an input, the Mapper algorithm outputs a graph representing the topological features of the whole dataset. This…

Algebraic Topology · Mathematics 2025-01-31 Yuyang Tao , Shufei Ge

Conventional histopathology has long been essential for disease diagnosis, relying on visual inspection of tissue sections. Immunohistochemistry aids in detecting specific biomarkers but is limited by its single-marker approach, restricting…

A wide range of data that appear in scientific experiments and simulations are multivariate or multifield in nature, consisting of multiple scalar fields. Topological feature search of such data aims to reveal important properties useful to…

Computational Geometry · Computer Science 2024-06-06 Tripti Agarwal , Amit Chattopadhyay , Vijay Natarajan

Detailed phenotype information is fundamental to accurate diagnosis and risk estimation of diseases. As a rich source of phenotype information, electronic health records (EHRs) promise to empower diagnostic variant interpretation. However,…

Machine Learning · Computer Science 2023-04-28 Shenghan Zhang , Haoxuan Li , Ruixiang Tang , Sirui Ding , Laila Rasmy , Degui Zhi , Na Zou , Xia Hu

As interactive web-based geovisualization becomes increasingly vital across disciplines, there is a growing need for open-source frameworks that support dynamic, multi-attribute spatial analysis and accessible design. This paper introduces…

Human-Computer Interaction · Computer Science 2025-09-10 Sarigai Sarigai , Liping Yang , Katie Slack , Carolyn Fish , Michaela Buenemann , Qiusheng Wu , Yan Lin , Joseph A. Cook , David Jacobs

Node-link diagrams are a popular method for representing graphs that capture relationships between individuals, businesses, proteins, and telecommunication endpoints. However, node-link diagrams may fail to convey insights regarding graph…

Social and Information Networks · Computer Science 2023-09-20 Paul Rosen , Mustafa Hajij , Bei Wang

Phylogenetic profiles - presence-absence patterns of genes across taxa - are rich information sources for inferring the evolutionary history of genes and gene families. When aggregated across many genes, these profiles can reveal…

Populations and Evolution · Quantitative Biology 2025-07-10 Vinh Tran , Ingo Ebersberger

Despite the popularity of information measures in analysis of probabilistic systems, proper tools for their visualization are not common. This work develops a simple matrix representation of information transfer in sequential systems,…

Information Theory · Computer Science 2024-05-28 Dor Tsur , Haim Permuter

The increased availability of electronic health records (EHRs) have spearheaded the initiative for precision medicine using data driven approaches. Essential to this effort is the ability to identify patients with certain medical conditions…

Topological analysis of the magnetic field in simulated plasmas allows the study of various physical phenomena in a wide range of settings. One such application is magnetic reconnection, a phenomenon related to the dynamics of the magnetic…

Plant phenotyping increasingly relies on (semi-)automated image-based analysis workflows to improve its accuracy and scalability. However, many existing solutions remain overly complex, difficult to reimplement and maintain, and pose high…

Mapper, a topological algorithm, is frequently used as an exploratory tool to build a graphical representation of data. This representation can help to gain a better understanding of the intrinsic shape of high-dimensional genomic data and…

Genomics · Quantitative Biology 2023-07-19 Erik J. Amézquita , Farzana Nasrin , Kathleen M. Storey , Masato Yoshizawa

Information visualization is essential in making sense out of large data sets. Often, high-dimensional data are visualized as a collection of points in 2-dimensional space through dimensionality reduction techniques. However, these…

Computational Geometry · Computer Science 2009-07-16 Emden R. Gansner , Yifan Hu , Stephen G. Kobourov

Scientific data sets continue to increase in both size and complexity. In the past, dedicated graphics systems at supercomputing centers were required to visualize large data sets, but as the price of commodity graphics hardware has dropped…

Instrumentation and Methods for Astrophysics · Physics 2015-05-19 P. R. Gazis , C. Levit , M. J. Way