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Nuclear magnetic resonance spectroscopy (MRS) allows for the determination of atomic structures and concentrations of different chemicals in a biochemical sample of interest. MRS is used in vivo clinically to aid in the diagnosis of several…

Medical Physics · Physics 2021-05-04 Zohaib Iqbal , Dan Nguyen , M. Albert Thomas , Steve Jiang

This paper considers a distributed stochastic strongly convex optimization, where agents connected over a network aim to cooperatively minimize the average of all agents' local cost functions. Due to the stochasticity of gradient estimation…

Optimization and Control · Mathematics 2020-02-17 Jinlong Lei , Peng Yi , Jie Chen , Yiguang Hong

The recent success of graph neural networks has significantly boosted molecular property prediction, advancing activities such as drug discovery. The existing deep neural network methods usually require large training dataset for each…

Machine Learning · Computer Science 2021-02-17 Zhichun Guo , Chuxu Zhang , Wenhao Yu , John Herr , Olaf Wiest , Meng Jiang , Nitesh V. Chawla

This paper studies learning the representations of whole graphs in both unsupervised and semi-supervised scenarios. Graph-level representations are critical in a variety of real-world applications such as predicting the properties of…

Machine Learning · Computer Science 2020-01-20 Fan-Yun Sun , Jordan Hoffmann , Vikas Verma , Jian Tang

The problem of unsupervised learning node embeddings in graphs is one of the important directions in modern network science. In this work we propose a novel framework, which is aimed to find embeddings by \textit{discriminating…

Machine Learning · Statistics 2020-01-24 Stanislav Tsepa , Maxim Panov

Molecule representation learning (MRL) methods aim to embed molecules into a real vector space. However, existing SMILES-based (Simplified Molecular-Input Line-Entry System) or GNN-based (Graph Neural Networks) MRL methods either take…

Machine Learning · Computer Science 2021-09-23 Hongwei Wang , Weijiang Li , Xiaomeng Jin , Kyunghyun Cho , Heng Ji , Jiawei Han , Martin D. Burke

Optimization problems over dynamic networks have been extensively studied and widely used in the past decades to formulate numerous real-world problems. However, (1) traditional optimization-based approaches do not scale to large networks,…

Machine Learning · Computer Science 2023-05-17 Daniele Gammelli , James Harrison , Kaidi Yang , Marco Pavone , Filipe Rodrigues , Francisco C. Pereira

The common graph Laplacian regularizer is well-established in semi-supervised learning and spectral dimensionality reduction. However, as a first-order regularizer, it can lead to degenerate functions in high-dimensional manifolds. The…

Computer Vision and Pattern Recognition · Computer Science 2016-02-12 Kwang In Kim , James Tompkin , Hanspeter Pfister , Christian Theobalt

Recently, deep generative models for molecular graphs are gaining more and more attention in the field of de novo drug design. A variety of models have been developed to generate topological structures of drug-like molecules, but…

Quantitative Methods · Quantitative Biology 2021-09-16 Yibo Li , Jianfeng Pei , Luhua Lai

We study stochastic graph optimization problems in a novel distributed setting. As in the standard centralized setting, a random subgraph $G^*$ of a known base graph $G$ is realized by including each edge $e$ independently with a known…

Data Structures and Algorithms · Computer Science 2026-05-21 Keren Censor-Hillel , Aditi Dudeja , George Giakkoupis

Deep neural networks are widely used in practical applications of AI, however, their inner structure and complexity made them generally not easily interpretable. Model transparency and interpretability are key requirements for multiple…

Machine Learning · Computer Science 2026-01-13 Luca Bergamin , Roberto Confalonieri , Fabio Aiolli

Distributionally robust supervised learning (DRSL) is emerging as a key paradigm for building reliable machine learning systems for real-world applications -- reflecting the need for classifiers and predictive models that are robust to the…

Machine Learning · Computer Science 2022-01-26 Yaodong Yu , Tianyi Lin , Eric Mazumdar , Michael I. Jordan

Magnetic Resonance Spectroscopy (MRS) provides valuable information to help with the identification and understanding of brain tumors, yet MRS is not a widely available medical imaging modality. Aiming to counter this issue, this research…

Computer Vision and Pattern Recognition · Computer Science 2018-08-24 Nathan J Olliverre , Guang Yang , Gregory Slabaugh , Constantino Carlos Reyes-Aldasoro , Eduardo Alonso

We present a new method for learning Soft Random Geometric Graphs (SRGGs), drawn in probabilistic metric spaces, with the connection function of the graph defined as the marginal posterior probability of an edge random variable, given the…

Methodology · Statistics 2020-02-05 Kangrui Wang , Dalia Chakrabarty

Reinforcement Learning algorithms are primarily focused on learning a policy that maximizes expected return. As a result, the learned policy can exploit one or few reward sources. However, in many natural situations, it is desirable to…

Machine Learning · Computer Science 2026-03-31 Sagalpreet Singh , Rishi Saket , Aravindan Raghuveer

Distributed learning paradigms, such as federated or decentralized learning, allow a collection of agents to solve global learning and optimization problems through limited local interactions. Most such strategies rely on a mixture of local…

Machine Learning · Computer Science 2023-10-27 Christian A. Schroth , Stefan Vlaski , Abdelhak M. Zoubir

In recent years, molecular graph representation learning (GRL) has drawn much more attention in molecular property prediction (MPP) problems. The existing graph methods have demonstrated that 3D geometric information is significant for…

Machine Learning · Computer Science 2022-12-01 Hao Zhang , Nan Zhang , Ruixin Zhang , Lei Shen , Yingyi Zhang , Meng Liu

Increasing interest in integrating advanced robotics within manufacturing has spurred a renewed concentration in developing real-time scheduling solutions to coordinate human-robot collaboration in this environment. Traditionally, the…

Robotics · Computer Science 2020-06-30 Zheyuan Wang , Matthew Gombolay

Optimising discrete data for a desired characteristic using gradient-based methods involves projecting the data into a continuous latent space and carrying out optimisation in this space. Carrying out global optimisation is difficult as…

Machine Learning · Computer Science 2019-05-27 Omar Mahmood , José Miguel Hernández-Lobato

Graph Machine Learning (GML) is receiving growing interest within the pharmaceutical and biotechnology industries for its ability to model biomolecular structures, the functional relationships between them, and integrate multi-omic datasets…