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In this thesis the aim is to work on optimizing the modern machine learning models for personalized forecasting of Alzheimer Disease (AD) Progression from clinical trial data. The data comes from the TADPOLE challenge, which is one of the…

Machine Learning · Computer Science 2020-08-07 Aritra Banerjee

Spreadsheet software is the tool of choice for interactive ad-hoc data management, with adoption by billions of users. However, spreadsheets are not scalable, unlike database systems. On the other hand, database systems, while highly…

Databases · Computer Science 2017-10-09 Mangesh Bendre , Vipul Venkataraman , Xinyan Zhou , Kevin Chang , Aditya Parameswaran

The integration of Large Language Models (LLMs) into healthcare promises to transform medical diagnostics, research, and patient care. Yet, the progression of medical LLMs faces obstacles such as complex training requirements, rigorous…

Machine Learning · Computer Science 2024-04-26 Emre Can Acikgoz , Osman Batur İnce , Rayene Bench , Arda Anıl Boz , İlker Kesen , Aykut Erdem , Erkut Erdem

Machine learning (ML) has the potential to revolutionize a wide range of research areas and industries, but many ML projects never progress past the proof-of-concept stage. To address this issue, we introduce Model Share AI (AIMS), an…

Software Engineering · Computer Science 2023-09-28 Heinrich Peters , Michael Parrott

Health informatics research is characterized by diverse data modalities, rapid knowledge expansion, and the need to integrate insights across biomedical science, data analytics, and clinical practice. These characteristics make it…

Artificial Intelligence · Computer Science 2025-09-24 Yuxiao Cheng , Jinli Suo

Artificial Intelligence (AI) and Large Language Models (LLMs) hold significant promise in revolutionizing healthcare, especially in clinical applications. Simultaneously, Digital Twin technology, which models and simulates complex systems,…

Artificial Intelligence · Computer Science 2024-09-27 Himanshu Pandey , Akhil Amod , Shivang , Kshitij Jaggi , Ruchi Garg , Abheet Jain , Vinayak Tantia

The recent surge in open-source Large Language Models (LLMs), such as LLaMA, Falcon, and Mistral, provides diverse options for AI practitioners and researchers. However, most LLMs have only released partial artifacts, such as the final…

The emergence of pathology foundation models has revolutionized computational histopathology, enabling highly accurate, generalized whole-slide image analysis for improved cancer diagnosis, and prognosis assessment. While these models show…

The adoption of cloud-based Enterprise Resource Planning (ERP) platforms such as Workday has transformed healthcare operations by integrating financial, supply-chain, and workforce processes into a unified ecosystem. However, traditional…

Software Engineering · Computer Science 2025-11-21 Monu Sharma

This paper quantitatively reveals the state-of-the-art and state-of-the-practice AI systems only achieve acceptable performance on the stringent conditions that all categories of subjects are known, which we call closed clinical settings,…

Pathology foundation models (PFMs) have rapidly advanced and are becoming a common backbone for downstream clinical tasks, offering strong transferability across tissues and institutions. However, for dense prediction (e.g., segmentation),…

Image and Video Processing · Electrical Eng. & Systems 2026-02-05 Weiming Chen , Xitong Ling , Xidong Wang , Zhenyang Cai , Yijia Guo , Mingxi Fu , Ziyi Zeng , Minxi Ouyang , Jiawen Li , Yizhi Wang , Tian Guan , Benyou Wang , Yonghong He

Continuous dynamical systems, characterized by differential equations, are ubiquitously used to model several important problems: plasma dynamics, flow through porous media, weather forecasting, and epidemic dynamics. Recently, a wide range…

Machine Learning · Computer Science 2023-10-04 Priyanshu Burark , Karn Tiwari , Meer Mehran Rashid , Prathosh A P , N M Anoop Krishnan

Computational modeling of cancer can help unveil dynamics and interactions that are hard to replicate experimentally. Thanks to the advancement in cancer databases and data analysis technologies, these models have become more robust than…

Quantitative Methods · Quantitative Biology 2023-11-07 Navid Mohammad Mirzaei , Leili Shahriyari

Machine learning models deployed in healthcare systems face data drawn from continually evolving environments. However, researchers proposing such models typically evaluate them in a time-agnostic manner, with train and test splits sampling…

Machine Learning · Computer Science 2022-11-15 Helen Zhou , Yuwen Chen , Zachary C. Lipton

This paper tries to reduce the effort of learning, deploying, and integrating several frameworks for the development of e-Science applications that combine simulations with High-Performance Data Analytics (HPDA). We propose a way to extend…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-07-10 Cristian Ramon-Cortes , Francesc Lordan , Jorge Ejarque , Rosa M. Badia

Artificial intelligence (AI) has the potential to transform healthcare by supporting more accurate diagnoses and personalized treatments. However, its adoption in practice remains constrained by fragmented data sources, strict privacy…

Software Engineering · Computer Science 2026-02-16 Mira Raheem , Amal Elgammal , Michael Papazoglou , Bernd Krämer , Neamat El-Tazi

Dynamic programming (DP) is a fundamental method in operations research, but formulating DP models has traditionally required expert knowledge of both the problem context and DP techniques. Large Language Models (LLMs) offer the potential…

Artificial Intelligence · Computer Science 2026-04-02 Chenyu Zhou , Jingyuan Yang , Linwei Xin , Yitian Chen , Ziyan He , Dongdong Ge

Three-dimensional medical image data and computer-aided decision making, particularly using deep learning, are becoming increasingly important in the medical field. To aid in these developments we introduce PR3DICTR: Platform for Research…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Daniel C. MacRae , Luuk van der Hoek , Robert van der Wal , Suzanne P. M. de Vette , Hendrike Neh , Baoqiang Ma , Peter M. A. van Ooijen , Lisanne V. van Dijk

Process mining has emerged as a powerful analytical technique for understanding complex healthcare workflows. However, its application faces significant barriers, including technical complexity, a lack of standardized approaches, and…

Artificial Intelligence · Computer Science 2026-02-11 Eduardo Illueca-Fernandez , Kaile Chen , Fernando Seoane , Farhad Abtahi

Therapeutics machine learning is an emerging field with incredible opportunities for innovatiaon and impact. However, advancement in this field requires formulation of meaningful learning tasks and careful curation of datasets. Here, we…

Machine Learning · Computer Science 2021-08-31 Kexin Huang , Tianfan Fu , Wenhao Gao , Yue Zhao , Yusuf Roohani , Jure Leskovec , Connor W. Coley , Cao Xiao , Jimeng Sun , Marinka Zitnik