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Sharing health and behavioral data raises significant privacy concerns, as conventional de-identification methods are susceptible to privacy attacks. Differential Privacy (DP) provides formal guarantees against re-identification risks, but…

Generally, the small size of public medical imaging datasets coupled with stringent privacy concerns, hampers the advancement of data-hungry deep learning models in medical imaging. This study addresses these challenges for 3D cardiac MRI…

Image and Video Processing · Electrical Eng. & Systems 2024-07-24 Deniz Daum , Richard Osuala , Anneliese Riess , Georgios Kaissis , Julia A. Schnabel , Maxime Di Folco

Enhancing reproducibility and data accessibility is essential to scientific research. However, ensuring data privacy while achieving these goals is challenging, especially in the medical field, where sensitive data are often commonplace.…

Methodology · Statistics 2025-09-24 Marta Cipriani , Lorenzo Di Rocco , Maria Puopolo , Marco Alfò

Generative adversarial networks (GANs) have been widely investigated for many potential applications in medical imaging. DatasetGAN is a recently proposed framework based on modern GANs that can synthesize high-quality segmented images…

Computer Vision and Pattern Recognition · Computer Science 2022-03-01 Zong Fan , Varun Kelkar , Mark A. Anastasio , Hua Li

Programmatically generated synthetic data has been used in differential private training for classification to enhance performance without privacy leakage. However, as the synthetic data is generated from a random process, the distribution…

Machine Learning · Computer Science 2024-12-16 Yujin Choi , Jinseong Park , Junyoung Byun , Jaewook Lee

Neuroimaging consortia can enhance reliability and generalizability of findings by pooling data across studies to achieve larger sample sizes. To adjust for site and MRI protocol effects, imaging datasets are often harmonized based on…

Quantitative Methods · Quantitative Biology 2024-03-04 Shruti P. Gadewar , Alyssa H. Zhu , Iyad Ba Gari , Sunanda Somu , Sophia I. Thomopoulos , Paul M. Thompson , Talia M. Nir , Neda Jahanshad

The usage of medical image data for the training of large-scale machine learning approaches is particularly challenging due to its scarce availability and the costly generation of data annotations, typically requiring the engagement of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-26 Joshua Niemeijer , Jan Ehrhardt , Hristina Uzunova , Heinz Handels

As a powerful technique in medical imaging, image synthesis is widely used in applications such as denoising, super resolution and modality transformation etc. Recently, the revival of deep neural networks made immense progress in the field…

Image and Video Processing · Electrical Eng. & Systems 2021-04-23 Gengyan Zhao , Mary E. Meyerand , Rasmus M. Birn

For sharing privacy-sensitive data, de-identification is commonly regarded as adequate for safeguarding privacy. Synthetic data is also being considered as a privacy-preserving alternative. Recent successes with numerical and tabular data…

Computation and Language · Computer Science 2025-03-05 Atiquer Rahman Sarkar , Yao-Shun Chuang , Noman Mohammed , Xiaoqian Jiang

Deep neural networks can form high-level hierarchical representations of input data. Various researchers have demonstrated that these representations can be used to enable a variety of useful applications. However, such representations are…

Computer Vision and Pattern Recognition · Computer Science 2020-02-25 Burkay Donderici , Caleb New , Chenliang Xu

As a pragmatic data augmentation tool, data synthesis has generally returned dividends in performance for deep learning based medical image analysis. However, generating corresponding segmentation masks for synthetic medical images is…

Image and Video Processing · Electrical Eng. & Systems 2023-03-23 Xiaodan Xing , Giorgos Papanastasiou , Simon Walsh , Guang Yang

Synthetic clinical data are increasingly important for advancing AI in healthcare, given strict privacy constraints on real-world EHRs, limited availability of annotated rare-condition data, and systemic biases in observational datasets.…

Machine Learning · Computer Science 2025-09-16 Rumeng Li , Xun Wang , Hong Yu

The biomedical field is among the sectors most impacted by the increasing regulation of Artificial Intelligence (AI) and data protection legislation, given the sensitivity of patient information. However, the rise of synthetic data…

Machine Learning · Computer Science 2024-04-26 Eric Macias-Fassio , Aythami Morales , Cristina Pruenza , Julian Fierrez

Supervised deep learning methods typically rely on large datasets for training. Ethical and practical considerations usually make it difficult to access large amounts of healthcare data, such as medical images, with known task-specific…

Medical Physics · Physics 2023-05-26 Marta Varela , Anil A Bharath

The difficulty of anonymizing text data hinders the development and deployment of NLP in high-stakes domains that involve private data, such as healthcare and social services. Poorly anonymized sensitive data cannot be easily shared with…

Computation and Language · Computer Science 2024-10-14 Krithika Ramesh , Nupoor Gandhi , Pulkit Madaan , Lisa Bauer , Charith Peris , Anjalie Field

Artificial intelligence (AI), machine learning, and deep learning (DL) methods are becoming increasingly important in the field of biomedical image analysis. However, to exploit the full potential of such methods, a representative number of…

Enabling highly secure applications (such as border crossing) with face recognition requires extensive biometric performance tests through large scale data. However, using real face images raises concerns about privacy as the laws do not…

Computer Vision and Pattern Recognition · Computer Science 2021-12-08 Marcel Grimmer , Haoyu Zhang , Raghavendra Ramachandra , Kiran Raja , Christoph Busch

This paper presents a soft-label anonymous gastric X-ray image distillation method based on a gradient descent approach. The sharing of medical data is demanded to construct high-accuracy computer-aided diagnosis (CAD) systems. However, the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Guang Li , Ren Togo , Takahiro Ogawa , Miki Haseyama

Psychiatric symptom identification on social media aims to infer fine-grained mental health symptoms from user-generated posts, allowing a detailed understanding of users' mental states. However, the construction of large-scale…

Computation and Language · Computer Science 2026-03-24 Migyeong Kang , Jihyun Kim , Hyolim Jeon , Sunwoo Hwang , Jihyun An , Yonghoon Kim , Haewoon Kwak , Jisun An , Jinyoung Han

The application of modern machine learning to retinal image analyses offers valuable insights into a broad range of human health conditions beyond ophthalmic diseases. Additionally, data sharing is key to fully realizing the potential of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Minkyu Jeon , Hyeonjin Park , Hyunwoo J. Kim , Michael Morley , Hyunghoon Cho