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The backpropagation of error algorithm used to train deep neural networks has been fundamental to the successes of deep learning. However, it requires sequential backward updates and non-local computations, which make it challenging to…

Neural and Evolutionary Computing · Computer Science 2022-02-22 Beren Millidge , Tommaso Salvatori , Yuhang Song , Rafal Bogacz , Thomas Lukasiewicz

Backpropagation has rapidly become the workhorse credit assignment algorithm for modern deep learning methods. Recently, modified forms of predictive coding (PC), an algorithm with origins in computational neuroscience, have been shown to…

Neural and Evolutionary Computing · Computer Science 2023-04-07 Umais Zahid , Qinghai Guo , Zafeirios Fountas

The backpropagation algorithm is an invaluable tool for training artificial neural networks; however, because of a weight sharing requirement, it does not provide a plausible model of brain function. Here, in the context of a two-layer…

Neural and Evolutionary Computing · Computer Science 2020-12-01 Siavash Golkar , David Lipshutz , Yanis Bahroun , Anirvan M. Sengupta , Dmitri B. Chklovskii

Backpropagation (BP) is the standard algorithm for training the deep neural networks that power modern artificial intelligence including large language models. However, BP is energy inefficient and unlikely to be implemented by the brain.…

Machine Learning · Computer Science 2025-10-30 Francesco Innocenti

Backpropagation is the default algorithm for training deep neural networks due to its simplicity, efficiency and high convergence rate. However, its requirements make it impossible to be implemented in a human brain. In recent years, more…

Machine Learning · Computer Science 2021-09-01 Albert Jiménez Sanfiz , Mohamed Akrout

Backpropagation of error (backprop) is a powerful algorithm for training machine learning architectures through end-to-end differentiation. However, backprop is often criticised for lacking biological plausibility. Recently, it has been…

Machine Learning · Computer Science 2020-10-07 Beren Millidge , Alexander Tschantz , Christopher L. Buckley

Artificial intelligence (AI) is rapidly becoming one of the key technologies of this century. The majority of results in AI thus far have been achieved using deep neural networks trained with a learning algorithm called error…

Artificial Intelligence · Computer Science 2025-10-30 Tommaso Salvatori , Ankur Mali , Christopher L. Buckley , Thomas Lukasiewicz , Rajesh P. N. Rao , Karl Friston , Alexander Ororbia

The neurons of artificial neural networks were originally invented when much less was known about biological neurons than is known today. Our work explores a modification to the core neuron unit to make it more parallel to a biological…

Neural and Evolutionary Computing · Computer Science 2025-01-31 Rorry Brenner , Laurent Itti

Research aimed at scaling up neuroscience inspired learning algorithms for neural networks is accelerating. Recently, a key research area has been the study of energy-based learning algorithms such as predictive coding, due to their…

Machine Learning · Computer Science 2026-01-30 Luca Pinchetti , Simon Frieder , Thomas Lukasiewicz , Tommaso Salvatori

Deep learning has redefined the field of artificial intelligence (AI) thanks to the rise of artificial neural networks, which are architectures inspired by their neurological counterpart in the brain. Through the years, this dualism between…

Machine Learning · Computer Science 2023-02-21 Tommaso Salvatori , Yuhang Song , Thomas Lukasiewicz , Rafal Bogacz , Zhenghua Xu

Deep neural networks excel at image classification, but their performance is far less robust to input perturbations than human perception. In this work we explore whether this shortcoming may be partly addressed by incorporating…

Computer Vision and Pattern Recognition · Computer Science 2021-11-05 Bhavin Choksi , Milad Mozafari , Callum Biggs O'May , Benjamin Ador , Andrea Alamia , Rufin VanRullen

There is an increasing convergence between biologically plausible computational models of inference and learning with local update rules and the global gradient-based optimization of neural network models employed in machine learning. One…

Machine Learning · Computer Science 2021-11-16 Andre Ofner , Raihan Kabir Ratul , Suhita Ghosh , Sebastian Stober

Predictive coding networks (PCNs) constitute a biologically inspired framework for understanding hierarchical computation in the brain, and offer an alternative to traditional feedforward neural networks in ML. This note serves as a quick,…

Neural and Evolutionary Computing · Computer Science 2025-06-10 Mikko Stenlund

Current artificial neural networks are trained with parameters encoded as floating point numbers that occupy lots of memory space at inference time. Due to the increase in the size of deep learning models, it is becoming very difficult to…

Machine Learning · Computer Science 2024-08-09 Ben Crulis , Barthelemy Serres , Cyril de Runz , Gilles Venturini

Backpropagation (BP) of errors is the backbone training algorithm for artificial neural networks (ANNs). It updates network weights through gradient descent to minimize a loss function representing the mismatch between predictions and…

Machine Learning · Statistics 2025-08-13 Davide Casnici , Charlotte Frenkel , Justin Dauwels

A large amount of recent research has the far-reaching goal of finding training methods for deep neural networks that can serve as alternatives to backpropagation (BP). A prominent example is predictive coding (PC), which is a…

Machine Learning · Computer Science 2022-11-08 Luca Pinchetti , Tommaso Salvatori , Yordan Yordanov , Beren Millidge , Yuhang Song , Thomas Lukasiewicz

Originally inspired by neurobiology, deep neural network models have become a powerful tool of machine learning and artificial intelligence, where they are used to approximate functions and dynamics by learning from examples. Here we give a…

Neurons and Cognition · Quantitative Biology 2019-04-12 Nikolaus Kriegeskorte , Tal Golan

Deep neural networks have become a pervasive tool in science and engineering. However, modern deep neural networks' growing energy requirements now increasingly limit their scaling and broader use. We propose a radical alternative for…

Machine Learning · Computer Science 2022-01-31 Logan G. Wright , Tatsuhiro Onodera , Martin M. Stein , Tianyu Wang , Darren T. Schachter , Zoey Hu , Peter L. McMahon

Ongoing studies have identified similarities between neural representations in biological networks and in deep artificial neural networks. This has led to renewed interest in developing analogies between the backpropagation learning…

Neural and Evolutionary Computing · Computer Science 2019-06-11 Theodore H. Moskovitz , Ashok Litwin-Kumar , L. F. Abbott

Predictive coding (PC) is a brain-inspired local learning algorithm that has recently been suggested to provide advantages over backpropagation (BP) in biologically relevant scenarios. While theoretical work has mainly focused on showing…

Neural and Evolutionary Computing · Computer Science 2023-06-01 Francesco Innocenti , Ryan Singh , Christopher L. Buckley
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