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I explain what is, what is not, and what is only sort of superresolution microscopy. I discuss optical resolution, first in terms of diffraction theory, then in terms of linear systems theory, and finally in terms of techniques that use…

Optics · Physics 2015-04-02 John Bechhoefer

Deep learning algorithms have seen acute growth of interest in their applications throughout several fields of interest in the last decade, with medical hyperspectral imaging being a particularly promising domain. So far, to the best of our…

Image and Video Processing · Electrical Eng. & Systems 2021-06-10 Uzair Khan , Paheding Sidike , Colin Elkin , Vijay Devabhaktuni

Deep learning has become a powerful tool in computational biology, revolutionising the analysis and interpretation of biological data over time. In our article review, we delve into various aspects of deep learning in computational biology.…

Biomedical photoacoustic tomography, which can provide high resolution 3D soft tissue images based on the optical absorption, has advanced to the stage at which translation from the laboratory to clinical settings is becoming possible. The…

Image and Video Processing · Electrical Eng. & Systems 2020-11-20 Andreas Hauptmann , Ben Cox

Performing super-resolution of a depth image using the guidance from an RGB image is a problem that concerns several fields, such as robotics, medical imaging, and remote sensing. While deep learning methods have achieved good results in…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Nando Metzger , Rodrigo Caye Daudt , Konrad Schindler

Modern-day display systems demand high-quality rendering. However, rendering at higher resolution requires a large number of data samples and is computationally expensive. Recent advances in deep learning-based image and video…

Graphics · Computer Science 2022-10-18 Sudarshan Devkota , Sumanta Pattanaik

Super-resolution reconstruction techniques entail the utilization of software algorithms to transform one or more sets of low-resolution images captured from the same scene into high-resolution images. In recent years, considerable…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Hao Yan , Zixiang Wang , Zhengjia Xu , Zhuoyue Wang , Zhizhong Wu , Ranran Lyu

Super-resolution microscopy has revolutionized optical fluorescence imaging by improving 3D resolution by 1-2 orders of magnitude. While different methods can successfully increase the resolution, all methods share significant differences…

Biological Physics · Physics 2015-01-26 Thomas Pengo , Nicolas Olivier , Suliana Manley

Deep learning is a branch of artificial intelligence where networks of simple interconnected units are used to extract patterns from data in order to solve complex problems. Deep learning algorithms have shown groundbreaking performance in…

Computer Vision and Pattern Recognition · Computer Science 2018-02-27 Maciej A. Mazurowski , Mateusz Buda , Ashirbani Saha , Mustafa R. Bashir

With the advent of Deep Learning (DL), Super-Resolution (SR) has also become a thriving research area. However, despite promising results, the field still faces challenges that require further research e.g., allowing flexible upsampling,…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Brian Moser , Federico Raue , Stanislav Frolov , Jörn Hees , Sebastian Palacio , Andreas Dengel

The diffraction of light imposes a fundamental limit on the resolution of light microscopes. This limit can be circumvented by creating and exploiting independent behaviors of the sample at length scales below the diffraction limit. In…

Biological Physics · Physics 2024-06-19 Mohamadreza Fazel , Michael J. Wester

Medical imaging is an invaluable resource in medicine as it enables to peer inside the human body and provides scientists and physicians with a wealth of information indispensable for understanding, modelling, diagnosis, and treatment of…

Image and Video Processing · Electrical Eng. & Systems 2022-08-25 Hanene Ben Yedder , Ben Cardoen , Ghassan Hamarneh

Magnetic resonance imaging (MRI) is extensively used for diagnosis and image-guided therapeutics. Due to hardware, physical and physiological limitations, acquisition of high-resolution MRI data takes long scan time at high system cost, and…

Medical Physics · Physics 2018-10-17 Qing Lyu , Chenyu You , Hongming Shan , Ge Wang

Optical microscopy has so far been restricted to superficial layers, leaving many important biological questions unanswered. Random scattering causes the ballistic focus, which is conventionally used for image formation, to decay…

Optics · Physics 2012-08-28 Ke Si , Reto Fiolka , Meng Cui

Super-resolution is aimed at reconstructing high-resolution images from low-resolution observations. State-of-the-art approaches underpinned with deep learning allow for obtaining outstanding results, generating images of high perceptual…

Computer Vision and Pattern Recognition · Computer Science 2025-03-20 Maciej Ziaja , Pawel Kowaleczko , Daniel Kostrzewa , Nicolas Longépé , Michal Kawulok

The establishment of image correspondence through robust image registration is critical to many clinical tasks such as image fusion, organ atlas creation, and tumor growth monitoring, and is a very challenging problem. Since the beginning…

Quantitative Methods · Quantitative Biology 2020-01-22 Grant Haskins , Uwe Kruger , Pingkun Yan

High-resolution (HR) magnetic resonance imaging (MRI) is crucial for many clinical and research applications. However, achieving it remains costly and constrained by technical trade-offs and experimental limitations. Super-resolution (SR)…

Super-resolution microscopy, or nanoscopy, enables the use of fluorescent-based molecular localization tools to study molecular structure at the nanoscale level in the intact cell, bridging the mesoscale gap to classical structural biology…

Subcellular Processes · Quantitative Biology 2024-05-28 Ivan R. Nabi , Ben Cardoen , Ismail M. Khater , Guang Gao , Timothy H. Wong , Ghassan Hamarneh

Accurately classifying white blood cells from microscopic images is essential to identify several illnesses and conditions in medical diagnostics. Many deep learning technologies are being employed to quickly and automatically classify…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Tatwadarshi P. Nagarhalli , Shruti S. Pawar , Soham A. Dahanukar , Uday Aswalekar , Ashwini M. Save , Sanket D. Patil

Recently, it was discovered that microsphere can generate super-resolution focusing beyond diffraction limit. This has led to the development of an exciting super-resolution imaging technique -microsphere nanoscopy- that features a record…

Optics · Physics 2021-08-26 Zengbo Wang