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Related papers: Phase field model for cell spreading dynamics

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The mechanosensitivity of cells, which determines how they are able to respond to mechanical signals received from their environment, is crucial for the functioning of all biological systems. In experiments, cells placed on cyclically…

Biological Physics · Physics 2019-01-17 John J. Molina , Ryoichi Yamamoto

We use the annealed formulation of complex networks to study the dynamical behavior of disease spreading on both static and adaptive networked systems. This unifying approach relies on the annealed adjacency matrix, representing one network…

Physics and Society · Physics 2010-11-09 Beniamino Guerra , Jesus Gomez-Gardenes

Tracking of plant cells in images obtained by microscope is a challenging problem due to biological phenomena such as large number of cells, non-uniform growth of different layers of the tightly packed plant cells and cell division.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Md Shazid Islam , Arindam Dutta , Calvin-Khang Ta , Kevin Rodriguez , Christian Michael , Mark Alber , G. Venugopala Reddy , Amit K. Roy-Chowdhury

The dispersal of cells from an initially constrained location is a crucial aspect of many physiological phenomena ranging from morphogenesis to tumour spreading. In such processes, the way cell-cell interactions impact the motion of single…

The phase-field method has become in recent years the method of choice for simulating microstructural pattern formation during solidification. One of its main advantages is that time-dependent three-dimensional simulations become feasible.…

Materials Science · Physics 2007-05-23 M. Dejmek , R. Folch , A. Parisi , M. Plapp

Cell-cell adhesion plays a vital role in the development and maintenance of multicellular organisms. One of its functions is regulation of cell migration, such as occurs, e.g. during embryogenesis or in cancer. In this work, we develop a…

Tissues and Organs · Quantitative Biology 2024-03-08 Anna Zhigun , Mabel Lizzy Rajendran

Cell migration is closely linked to cell shape, yet cell size is often assumed to remain constant. This assumption is challenged by recent experiments showing that cells undergo volume loss during spreading and swelling upon activation,…

Biological Physics · Physics 2025-05-28 Jonathan E. Ron , Ram M. Adar

Observations of single epidermal cells on flat adhesive substrates have revealed two distinct morphological and functional states, namely a non-migrating symmetric unpolarized state and a migrating asymmetric polarized state. These states…

Biological Physics · Physics 2010-04-14 Wolfgang Alt , Martin Bock , Christoph Möhl

The description of surface-diffusion controlled dynamics via the phase-field method is less trivial than it appears at first sight. A seemingly straightforward approach from the literature is shown to fail to produce the correct…

Computational Physics · Physics 2017-03-13 Clemens Mueller-Gugenberger , Robert Spatschek , Klaus Kassner

Experiments suggest that the migration of some cells in the three-dimensional extra cellular matrix bears strong resemblance to one-dimensional cell migration. Motivated by this observation, we construct and study a minimal one-dimensional…

Soft Condensed Matter · Physics 2015-06-22 J. H. Lopez , Moumita Das , J. M. Schwarz

Spatial self-organization emerges in distributed systems exhibiting local interactions when nonlinearities and the appropriate propagation of signals are at work. These kinds of phenomena can be modeled with different frameworks, typically…

Cell Behavior · Quantitative Biology 2016-11-23 Adriano Bonforti , Salva Duran-Nebreda , Raul Montañez , Ricard Solé

Experimental data regarding auxin and venation formation exist at both macroscopic and molecular scales, and we attempt to unify them into a comprehensive model for venation formation. We begin with a set of principles to guide an abstract…

Quantitative Methods · Quantitative Biology 2009-05-28 Pavel Dimitrov , Steven W. Zucker

In the framework of a phase field model of a single cell crawling on a substrate, we investigate how the properties of the cell membrane affect the shape and motility of the cell. Since the membrane influences the cell dynamics on multiple…

Soft Condensed Matter · Physics 2016-03-23 Benjamin Winkler , Igor S. Aranson , Falko Ziebert

We develop a first-principles scaling theory of the spreading of three-dimensional (3D) magnetic reconnection of finite extent in the out of plane direction. This theory addresses systems with or without an out of plane (guide) magnetic…

Plasma Physics · Physics 2021-08-25 Milton Arencibia , Paul A. Cassak , Michael A. Shay , Eric R. Priest

Open-cell graphitic foams were fabricated by chemical vapor deposition using nickel templates and their compressive responses were measured over a range of relative densities. The mechanical response required an interpretation in terms of a…

We study the contact process on a class of evolving scale-free networks, where each node updates its connections at independent random times. We give a rigorous mathematical proof that there is a transition between a phase where for all…

Probability · Mathematics 2015-12-03 Emmanuel Jacob , Peter Mörters

We simulate the electrical response of multiple disjoint biological 3D cells undergoing an electropermeabilization process. Instead of solving the boundary value problem in the unbounded volume, we reduce it to a system of boundary…

Computational Engineering, Finance, and Science · Computer Science 2024-09-04 Isabel A. Martínez Ávila , Carlos Jerez-Hanckes , Irina Pettersson

The chemical step is an elementary pattern in chemically heterogeneous substrates, featuring two regions of different wettability separated by a sharp border. Within the framework of lubrication theory, we investigate droplet motion and the…

Fluid Dynamics · Physics 2026-04-24 Zhuo Long , Peng Gao

Cell motility in higher organisms (eukaryotes) is crucial to biological functions ranging from wound healing to immune response, and also implicated in diseases such as cancer. For cells crawling on hard surfaces, significant insights into…

Soft Condensed Matter · Physics 2015-06-24 E. Tjhung , A. Tiribocchi , D. Marenduzzo , M. E. Cates

Models of folding of a triangular lattice embedded in a discrete space are studied as simple models of the crumpling transition of fixed-connectivity membranes. Both the case of planar folding and three-dimensional folding on a…

Statistical Mechanics · Physics 2008-02-03 Mark Bowick , Philippe Di Francesco , Olivier Golinelli , Emmanuel Guitter
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