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Deep neural networks for medical image reconstruction are traditionally trained using high-quality ground-truth images as training targets. Recent work on Noise2Noise (N2N) has shown the potential of using multiple noisy measurements of the…

Image and Video Processing · Electrical Eng. & Systems 2021-12-21 Weijie Gan , Yu Sun , Cihat Eldeniz , Jiaming Liu , Hongyu An , Ulugbek S. Kamilov

Humans can robustly learn novel visual concepts even when images undergo various deformations and lose certain information. Mimicking the same behavior and synthesizing deformed instances of new concepts may help visual recognition systems…

Computer Vision and Pattern Recognition · Computer Science 2019-07-19 Zitian Chen , Yanwei Fu , Yu-Xiong Wang , Lin Ma , Wei Liu , Martial Hebert

Deep learning has revolutionized image registration by its ability to handle diverse tasks while achieving significant speed advantages over conventional approaches. Current approaches, however, often employ globally uniform smoothness…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Xiang Chen , Fengting Zhang , Qinghao Liu , Min Liu , Kun Wu , Yaonan Wang , Hang Zhang

Rigid registration aims to determine the translations and rotations necessary to align features in a pair of images. While recent machine learning methods have become state-of-the-art for linear and deformable registration across subjects,…

Image and Video Processing · Electrical Eng. & Systems 2025-12-08 Jingru Fu , Adrian V. Dalca , Bruce Fischl , Rodrigo Moreno , Malte Hoffmann

Deep learning models have a large number of free parameters that must be estimated by efficient training of the models on a large number of training data samples to increase their generalization performance. In real-world applications, the…

Computer Vision and Pattern Recognition · Computer Science 2018-02-15 Hojjat Salehinejad , Shahrokh Valaee , Timothy Dowdell , Joseph Barfett

Deformable registration is a fundamental task in medical image processing, aiming to achieve precise alignment by establishing nonlinear correspondences between images. Traditional methods offer good adaptability and interpretability but…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Jing Hu , Kaiwei Yu , Hongjiang Xian , Shu Hu , Xin Wang

Deep learning methods have recently made notable advances in the tasks of classification and representation learning. These tasks are important for brain imaging and neuroscience discovery, making the methods attractive for porting to a…

Neural and Evolutionary Computing · Computer Science 2014-02-20 Sergey M. Plis , Devon R. Hjelm , Ruslan Salakhutdinov , Vince D. Calhoun

The recent statistical theory of neural networks focuses on nonparametric denoising problems that treat randomness as additive noise. Variability in image classification datasets does, however, not originate from additive noise but from…

Statistics Theory · Mathematics 2025-08-19 Juntong Chen , Sophie Langer , Johannes Schmidt-Hieber

Nonlinear image registration continues to be a fundamentally important tool in medical image analysis. Diagnostic tasks, image-guided surgery and radiotherapy as well as motion analysis all rely heavily on accurate intra-patient alignment.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Mattias P. Heinrich

Objective: Deformable brain MR image registration is challenging due to large inter-subject anatomical variation. For example, the highly complex cortical folding pattern makes it hard to accurately align corresponding cortical structures…

Computer Vision and Pattern Recognition · Computer Science 2019-02-07 Dongming Wei , Zhengwang Wu , Gang Li , Xiaohuan Cao , Dinggang Shen , Qian Wang

Image registration is used in many medical image analysis applications, such as tracking the motion of tissue in cardiac images, where cardiac kinematics can be an indicator of tissue health. Registration is a challenging problem for deep…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Benjamin Graham

In this work, we address the problem of improvement of robustness of feature representations learned using convolutional neural networks (CNNs) to image deformation. We argue that higher moment statistics of feature distributions could be…

Computer Vision and Pattern Recognition · Computer Science 2017-07-26 Zhun Sun , Mete Ozay , Takayuki Okatani

Deformable image registration plays a critical role in various tasks of medical image analysis. A successful registration algorithm, either derived from conventional energy optimization or deep networks requires tremendous efforts from…

Computer Vision and Pattern Recognition · Computer Science 2023-08-15 Xin Fan , Zi Li , Ziyang Li , Xiaolin Wang , Risheng Liu , Zhongxuan Luo , Hao Huang

Most of the deep learning based medical image registration algorithms focus on brain image registration tasks.Compared with brain registration, the chest CT registration has larger deformation, more complex background and region over-lap.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Cheng Wang , Qiyu Gao , Fandong Zhang , Shu Zhang , Yizhou Yu

In this paper, we introduce a novel deep-learning method to align cross-spectral images. Our approach relies on a learned descriptor which is invariant to different spectra. Multi-modal images of the same scene capture different signals and…

Computer Vision and Pattern Recognition · Computer Science 2021-10-06 Nati Ofir , Shai Silberstein , Hila Levi , Dani Rozenbaum , Yosi Keller , Sharon Duvdevani Bar

Deformable image registration remains a fundamental task in clinical practice, yet solving registration problems involving complex deformations remains challenging. Current deep learning-based registration methods employ continuous…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Haiqiao Wang , Dong Ni , Yi Wang

This study investigates the use of the unsupervised deep learning framework VoxelMorph for deformable registration of longitudinal abdominopelvic CT images acquired in patients with bone metastases from breast cancer. The CT images were…

This paper presents a novel predictive model, MetaMorph, for metamorphic registration of images with appearance changes (i.e., caused by brain tumors). In contrast to previous learning-based registration methods that have little or no…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Jian Wang , Jiarui Xing , Jason Druzgal , William M. Wells , Miaomiao Zhang

Deformable templates, or atlases, are images that represent a prototypical anatomy for a population, and are often enhanced with probabilistic anatomical label maps. They are commonly used in medical image analysis for population studies…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Marianne Rakic , Andrew Hoopes , S. Mazdak Abulnaga , Mert R. Sabuncu , John V. Guttag , Adrian V. Dalca

Deep convolutional neural networks trained on large datsets have emerged as an intriguing alternative for compressing images and solving inverse problems such as denoising and compressive sensing. However, it has only recently been realized…

Machine Learning · Computer Science 2019-07-09 Reinhard Heckel