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Physical imaging is a foundational characterization method in areas from condensed matter physics and chemistry to astronomy and spans length scales from atomic to universe. Images encapsulate crucial data regarding atomic bonding,…

Electron, optical, and scanning probe microscopy methods are generating ever increasing volume of image data containing information on atomic and mesoscale structures and functionalities. This necessitates the development of the machine…

Machine Learning · Computer Science 2023-04-03 Mani Valleti , Yongtao Liu , Sergei Kalinin

We show that unsupervised machine learning can be used to learn physical and chemical transformation pathways from the observational microscopic data, as demonstrated for atomically resolved images in Scanning Transmission Electron…

A shift-invariant variational autoencoder (shift-VAE) is developed as an unsupervised method for the analysis of spectral data in the presence of shifts along the parameter axis, disentangling the physically-relevant shifts from other…

Disordered Systems and Neural Networks · Physics 2021-04-22 Yongtao Liu , Rama K. Vasudevan , Kyle Kelley , Dohyung Kim , Yogesh Sharma , Mahshid Ahmadi , Sergei V. Kalinin , Maxim Ziatdinov

In situ scanning transmission electron microscopy enables observation of the domain dynamics in ferroelectric materials as a function of externally applied bias and temperature. The resultant data sets contain a wealth of information on…

Recent advances in imaging from celestial objects in astronomy visualized via optical and radio telescopes to atoms and molecules resolved via electron and probe microscopes are generating immense volumes of imaging data, containing…

Data Analysis, Statistics and Probability · Physics 2021-04-22 Maxim Ziatdinov , Sergei Kalinin

The 4D scanning transmission electron microscopy (STEM) method has enabled mapping of the structure and functionality of solids on the atomic scale, yielding information-rich data sets containing information on the interatomic electric and…

Computational Physics · Physics 2020-09-24 Mark P. Oxley , Maxim Ziatdinov , Ondrej Dyck , Andrew R. Lupini , Rama Vasudevan , Sergei V. Kalinin

A variational autoencoder (VAE) is a probabilistic machine learning framework for posterior inference that projects an input set of high-dimensional data to a lower-dimensional, latent space. The latent space learned with a VAE offers…

Machine Learning · Computer Science 2022-11-16 Rafael Pastrana

An approach for the analysis of atomically resolved scanning transmission electron microscopy data with multiple ferroic variants in the presence of imaging non-idealities and chemical variabilities based on a rotationally invariant…

Variational autoencoders (VAEs) are a popular class of deep generative models with many variants and a wide range of applications. Improvements upon the standard VAE mostly focus on the modelling of the posterior distribution over the…

Machine Learning · Computer Science 2022-11-02 James Langley , Miguel Monteiro , Charles Jones , Nick Pawlowski , Ben Glocker

Variational Auto-Encoder (VAE) has been widely applied as a fundamental generative model in machine learning. For complex samples like imagery objects or scenes, however, VAE suffers from the dimensional dilemma between reconstruction…

Machine Learning · Computer Science 2020-02-18 Deli Zhao , Jiapeng Zhu , Bo Zhang

Variational autoencoders (VAEs) have been used extensively to discover low-dimensional latent factors governing neural activity and animal behavior. However, without careful model selection, the uncovered latent factors may reflect noise in…

Machine Learning · Computer Science 2023-12-13 Julia Huiming Wang , Dexter Tsin , Tatiana Engel

Scanning transmission electron microscopy (STEM) is now the primary tool for exploring functional materials on the atomic level. Often, features of interest are highly localized in specific regions in the material, such as ferroelectric…

Materials Science · Physics 2021-08-11 Nicole Creange , Ondrej Dyck , Rama K. Vasudevan , Maxim Ziatdinov , Sergei V. Kalinin

The key idea of variational auto-encoders (VAEs) resembles that of traditional auto-encoder models in which spatial information is supposed to be explicitly encoded in the latent space. However, the latent variables in VAEs are vectors,…

Machine Learning · Computer Science 2019-01-23 Zhengyang Wang , Hao Yuan , Shuiwang Ji

Scientific archives now contain hundreds of petabytes of data across genomics, ecology, climate, and molecular biology that could reveal undiscovered patterns if systematically analyzed at scale. Large-scale, weakly-supervised datasets in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Samuel Stevens , Jacob Beattie , Tanya Berger-Wolf , Yu Su

Automotive telemetry data exhibits slow drifts and fast spikes, often within the same sequence, making reliable anomaly detection challenging. Standard reconstruction-based methods, including sequence variational autoencoders (VAEs), use a…

Machine Learning · Computer Science 2026-03-12 Kadir-Kaan Özer , René Ebeling , Markus Enzweiler

Learning rich data representations from unlabeled data is a key challenge towards applying deep learning algorithms in downstream tasks. Several variants of variational autoencoders (VAEs) have been proposed to learn compact data…

Computer Vision and Pattern Recognition · Computer Science 2024-01-11 Pan Xiao , Peijie Qiu , Sungmin Ha , Abdalla Bani , Shuang Zhou , Aristeidis Sotiras

Optimal computations under uncertainty require an adequate probabilistic representation about beliefs. Deep generative models, and specifically Variational Autoencoders (VAEs), have the potential to meet this demand by building latent…

Unsupervised visual anomaly detection conveys practical significance in many scenarios and is a challenging task due to the unbounded definition of anomalies. Moreover, most previous methods are application-specific, and establishing a…

Computer Vision and Pattern Recognition · Computer Science 2022-11-02 Haiming Yao , Xue Wang , Wenyong Yu

Estimation of uncertainty in deep learning models is of vital importance, especially in medical imaging, where reliance on inference without taking into account uncertainty could lead to misdiagnosis. Recently, the probabilistic Variational…

Machine Learning · Computer Science 2020-10-20 Haleh Akrami , Anand A. Joshi , Sergul Aydore , Richard M. Leahy
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