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The Burrows-Wheeler Transform (BWT) is a string transformation technique widely used in areas such as bioinformatics and file compression. Many applications combine a run-length encoding (RLE) with the BWT in a way which preserves the…

Discrete Mathematics · Computer Science 2025-09-18 Lily Major , Amanda Clare , Jacqueline W. Daykin , Benjamin Mora , Christine Zarges

The Burrows-Wheeler-Transform (BWT), a reversible string transformation, is one of the fundamental components of many current data structures in string processing. It is central in data compression, as well as in efficient query algorithms…

Data Structures and Algorithms · Computer Science 2024-04-16 Sara Giuliani , Shunsuke Inenaga , Zsuzsanna Lipták , Nicola Prezza , Marinella Sciortino , Anna Toffanello

Due to the exponential growth of genomic data, constructing dedicated data structures has become the principal bottleneck in common bioinformatics applications. In particular, the Burrows-Wheeler Transform (BWT) is the basis of some of the…

Data Structures and Algorithms · Computer Science 2023-05-15 Francesco Masillo

The Burrows-Wheeler transform (BWT) is a well studied text transformation widely used in data compression and text indexing. The BWT of two strings can also provide similarity measures between them, based on the observation that the more…

Data Structures and Algorithms · Computer Science 2020-09-10 Felipe A. Louza , Guilherme P. Telles , Simon Gog , Liang Zhao

The Burrows-Wheeler Transform (BWT) is often taught in undergraduate courses on algorithmic bioinformatics, because it underlies the FM-index and thus important tools such as Bowtie and BWA. Its admirers consider the BWT a thing of beauty…

Data Structures and Algorithms · Computer Science 2022-08-23 Travis Gagie , Giovanni Manzini , Marinella Sciortino

The Burrows-Wheeler Transform (BWT) is a fundamental component in many data structures for text indexing and compression, widely used in areas such as bioinformatics and information retrieval. The extended BWT (eBWT) generalizes the…

Data Structures and Algorithms · Computer Science 2025-06-06 Florian Ingels , Anaïs Denis , Bastien Cazaux

Highly-repetitive collections of strings are increasingly being amassed by genome sequencing and genetic variation experiments, as well as by storing all versions of human-generated files, like webpages and source code. Existing indexes for…

Data Structures and Algorithms · Computer Science 2016-04-22 Djamal Belazzougui , Fabio Cunial , Travis Gagie , Nicola Prezza , Mathieu Raffinot

One of the most well-known variants of the Burrows-Wheeler transform (BWT) [Burrows and Wheeler, 1994] is the bijective BWT (BBWT) [Gil and Scott, arXiv 2012], which applies the extended BWT (EBWT) [Mantaci et al., TCS 2007] to the multiset…

Data Structures and Algorithms · Computer Science 2020-04-28 Dominik Köppl , Daiki Hashimoto , Diptarama Hendrian , Ayumi Shinohara

The Burrows-Wheeler transform (BWT) is integral to the FM-index, which is used extensively in text compression, indexing, pattern search, and bioinformatic problems as de novo assembly and read alignment. Thus, efficient construction of the…

Data Structures and Algorithms · Computer Science 2025-02-04 Enno Adler , Stefan Böttcher , Rita Hartel , Cederic Alexander Steininger

Motivation: Burrows-Wheeler Transform (BWT) is a common component in full-text indices. Initially developed for data compression, it is particularly powerful for encoding redundant sequences such as pangenome data. However, BWT construction…

Genomics · Quantitative Biology 2025-09-10 Heng Li

We propose algorithms that, given the input string of length $n$ over integer alphabet of size $\sigma$, construct the Burrows-Wheeler transform (BWT), the permuted longest-common-prefix (PLCP) array, and the LZ77 parsing in…

Data Structures and Algorithms · Computer Science 2020-12-09 Dominik Kempa

Some recent results have introduced external-memory algorithms to compute self-indexes of a set of strings, mainly via computing the Burrows-Wheeler Transform (BWT) of the input strings. The motivations for those results stem from…

Data Structures and Algorithms · Computer Science 2015-06-12 Paola Bonizzoni , Gianluca Della Vedova , Yuri Pirola , Marco Previtali , Raffaella Rizzi

We show how to build several data structures of central importance to string processing, taking as input the Burrows-Wheeler transform (BWT) and using small extra working space. Let $n$ be the text length and $\sigma$ be the alphabet size.…

Data Structures and Algorithms · Computer Science 2019-08-14 Nicola Prezza , Giovanna Rosone

The Burrows-Wheeler Transform (BWT) is among the most influential discoveries in text compression and DNA storage. It is a reversible preprocessing step that rearranges an $n$-letter string into runs of identical characters (by exploiting…

Data Structures and Algorithms · Computer Science 2018-12-06 Sandip Sinha , Omri Weinstein

The Positional Burrows--Wheeler Transform (PBWT) is a data structure designed for efficiently representing and querying large collections of sequences, such as haplotype panels in genomics. Forward and backward stepping operations --…

Data Structures and Algorithms · Computer Science 2026-02-17 Paola Bonizzoni , Davide Cozzi , Younan Gao

In order to avoid the reference bias introduced by mapping reads to a reference genome, bioinformaticians are investigating reference-free methods for analyzing sequenced genomes. With large projects sequencing thousands of individuals,…

Data Structures and Algorithms · Computer Science 2016-01-15 Jouni Sirén

Recently, Cenzato et al.\ proposed a new text index, called the \emph{suffixient array}, which is a subset of the suffix array and supports locating a single pattern occurrence or finding its maximal exact matches (MEMs), assuming random…

Data Structures and Algorithms · Computer Science 2026-05-07 Paola Bonizzoni , Younan Gao , Brian Riccardi

The Burrows-Wheeler Transform (BWT) has been an essential tool in text compression and indexing. First introduced in 1994, it went on to provide the backbone for the first encoding of the classic suffix tree data structure in space close to…

Data Structures and Algorithms · Computer Science 2020-02-19 Jason Bentley , Daniel Gibney , Sharma V. Thankachan

Indexing highly repetitive strings (i.e., strings with many repetitions) for fast queries has become a central research topic in string processing, because it has a wide variety of applications in bioinformatics and natural language…

Data Structures and Algorithms · Computer Science 2021-04-19 Takaaki Nishimoto , Yasuo Tabei

While short read aligners, which predominantly use the FM-index, are able to easily index one or a few human genomes, they do not scale well to indexing databases containing thousands of genomes. To understand why, it helps to examine the…

Data Structures and Algorithms · Computer Science 2018-11-19 Alan Kuhnle , Taher Mun , Christina Boucher , Travis Gagie , Ben Langmead , Giovanni Manzini