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We consider the optimal strategy for laboratory testing of biological samples when we wish to know the results for each sample rather than the average prevalence of positive samples. If the proportion of positive samples is low considerable…

Quantitative Methods · Quantitative Biology 2010-07-29 Brian G. Williams

The problem of Group Testing is to identify defective items out of a set of objects by means of pool queries of the form "Does the pool contain at least a defective?". The aim is of course to perform detection with the fewest possible…

Statistical Mechanics · Physics 2009-11-13 M. Mézard , M. Tarzia , C. Toninelli

As humanity struggles to contain the global Covid-19 infection, prophylactic actions are grandly slowed down by the shortage of testing kits. Governments have taken several measures to work around this shortage: the FDA has become more…

The cataclysmic contagion based calamity -- Covid-19 has shown us a clear need for a comprehensive community based strategy that overcomes the sheer complexity of controlling it and the caveats of current methods. In this regard, as seen in…

Physics and Society · Physics 2021-09-17 Surya Dheeshjith , Inavamsi Enaganti , Bud Mishra

We consider the problem of detecting a small subset of defective items from a large set via non-adaptive "random pooling" group tests. We consider both the case when the measurements are noiseless, and the case when the measurements are…

Information Theory · Computer Science 2011-07-25 Chun Lam Chan , Pak Hou Che , Sidharth Jaggi , Venkatesh Saligrama

The usual problem for group testing is this: For a given number of individuals and a given prevalence, how many tests T* are required to find every infected individual? In real life, however, the problem is usually different: For a given…

Applications · Statistics 2021-07-21 Matthew Aldridge

In this paper, we consider the problem of designing optimal pooling matrix for group testing (for example, for COVID-19 virus testing) with the constraint that no more than $r>0$ samples can be pooled together, which we call "dilution…

Quantitative Methods · Quantitative Biology 2020-08-06 Jirong Yi , Myung Cho , Xiaodong Wu , Raghu Mudumbai , Weiyu Xu

We have a large number of samples and we want to find the infected ones using as few number of tests as possible. We can use group testing which tells about a small group of people whether at least one of them is infected. Group testing is…

Quantitative Methods · Quantitative Biology 2020-05-07 Endre Csóka

We consider the problem of hypothesis testing for discrete distributions. In the standard model, where we have sample access to an underlying distribution $p$, extensive research has established optimal bounds for uniformity testing,…

Machine Learning · Computer Science 2024-12-03 Maryam Aliakbarpour , Piotr Indyk , Ronitt Rubinfeld , Sandeep Silwal

Consider a collection of objects, some of which may be `bad', and a test which determines whether or not a given sub-collection contains no bad objects. The non-adaptive pooling (or group testing) problem involves identifying the bad…

Combinatorics · Mathematics 2016-09-06 David J. Balding , David C. Torney

We formulate and analyze a stochastic threshold group testing problem motivated by biological applications. Here a set of $n$ items contains a subset of $d \ll n$ defective items. Subsets (pools) of the $n$ items are tested -- the test…

Information Theory · Computer Science 2013-04-25 Chun Lam Chan , Sheng Cai , Mayank Bakshi , Sidharth Jaggi , Venkatesh Saligrama

Group testing is the process of pooling arbitrary subsets from a set of $n$ items so as to identify, with a minimal number of tests, a "small" subset of $d$ defective items. In "classical" non-adaptive group testing, it is known that when…

Information Theory · Computer Science 2018-09-21 Venkata Gandikota , Elena Grigorescu , Sidharth Jaggi , Samson Zhou

Choosing an optimal strategy for hierarchical group testing is an important problem for practitioners who are interested in disease screening with limited resources. For example, when screening for infectious diseases in large populations,…

Methodology · Statistics 2020-02-27 Yaakov Malinovsky , Gregory Haber , Paul S. Albert

In order to identify the infected individuals of a population, their samples are divided in equally sized groups called pools and a single laboratory test is applied to each pool. Individuals whose samples belong to pools that test negative…

Statistics Theory · Mathematics 2021-10-06 Inés Armendáriz , Pablo A. Ferrari , Daniel Fraiman , José M. Martínez , Silvina Ponce Dawson

The group testing problem concerns discovering a small number of defective items within a large population by performing tests on pools of items. A test is positive if the pool contains at least one defective, and negative if it contains no…

Information Theory · Computer Science 2026-05-15 Matthew Aldridge , Oliver Johnson , Jonathan Scarlett

In this paper, we propose algorithms that leverage a known community structure to make group testing more efficient. We consider a population organized in connected communities: each individual participates in one or more communities, and…

Information Theory · Computer Science 2021-03-18 Pavlos Nikolopoulos , Sundara Rajan Srinivasavaradhan , Tao Guo , Christina Fragouli , Suhas Diggavi

We present a method for efficient estimation of the prevalence of infection in a population with high accuracy using only a small number of tests. The presented approach uses pool testing with a mix of pool sizes of various sizes. The test…

Applications · Statistics 2020-04-08 Itsik Bergel

Executing various sequences of system functions in a system under test represents one of the primary techniques in software testing. The natural way to create effective, consistent and efficient test sequences is to model the system under…

Software Engineering · Computer Science 2019-12-05 Miroslav Bures , Bestoun S. Ahmed

Large-scale testing is crucial in pandemic containment, but resources are often prohibitively constrained. We study the optimal application of pooled testing for populations that are heterogeneous with respect to an individual's infection…

Computer Science and Game Theory · Computer Science 2023-09-22 Simon Finster , Michelle González Amador , Edwin Lock , Francisco Marmolejo-Cossío , Evi Micha , Ariel D. Procaccia

We consider some computationally efficient and provably correct algorithms with near-optimal sample-complexity for the problem of noisy non-adaptive group testing. Group testing involves grouping arbitrary subsets of items into pools. Each…

Information Theory · Computer Science 2016-11-18 Chun Lam Chan , Sidharth Jaggi , Venkatesh Saligrama , Samar Agnihotri
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