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Due to its ability to summarise 'real-time' epidemic behaviour, the time-dependent reproduction number, Rt, is a useful metric for tracking pathogen transmission and quantifying the effects of interventions during infectious disease…

Populations and Evolution · Quantitative Biology 2026-03-12 Ioana Bouros , Robin Thompson , David Gavaghan , Ben Lambert

The transmission rate of many acute infectious diseases varies significantly in time, but the underlying mechanisms are usually uncertain. They may include seasonal changes in the environment, contact rate, immune system response, etc. The…

Quantitative Methods · Quantitative Biology 2011-06-17 Mark Pollicott , Hao Wang , Howie Weiss

Policy-makers require data-driven tools to assess the spread of COVID-19 and inform the public of their risk of infection on an ongoing basis. We propose a rigorous hybrid model-and-data-driven approach to risk scoring based on a…

In this paper, we present a discrete-time networked SEIR model using population flow, its derivation, and assumptions under which this model is well defined. We identify properties of the system's equilibria, namely the healthy states. We…

Systems and Control · Electrical Eng. & Systems 2021-04-16 Brooks Butler , Ciyuan Zhang , Ian Walter , Nishant Nair , Raphael Stern , Philip E. Paré

The mobility patterns of individuals in China during the early outbreak of the COVID-19 pandemic exhibit reversible changes -- in many regions, the mobility first decreased significantly and later restored. Based on this observation, here…

Physics and Society · Physics 2022-10-25 Xincheng Shu , Zhongyuan Ruan

The spread of infectious epidemics is often accelerated by super-spreader events. Understanding their effect is important, particularly in the context of standard epidemiological models, which require estimates for parameters such as $R_0$.…

Populations and Evolution · Quantitative Biology 2021-03-29 Harisankar Ramaswamy , Assad A Oberai , Mitul Luhar , Yannis C Yortsos

This paper investigates a behavioral-feedback SIR model in which the infection rate adapts dynamically based on the fractions of susceptible and infected individuals. We introduce an invariant of motion and we characterize the peak of…

Populations and Evolution · Quantitative Biology 2025-09-17 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

Pandemics can cause immense disruption and damage to communities and societies. Thus far, modeling of pandemics has focused on either large-scale difference equation models like the SIR and the SEIR models, or detailed micro-level…

Multiagent Systems · Computer Science 2010-07-27 Teruhiko Yoneyama , Sanmay Das , Mukkai Krishnamoorthy

What role do asymptomatically infected individuals play in the transmission dynamics? There are many diseases, such as norovirus and influenza, where some infected hosts show symptoms of the disease while others are asymptomatically…

Populations and Evolution · Quantitative Biology 2018-01-29 Ka Yin Leung , Pieter Trapman , Tom Britton

In this paper, we study the effectiveness of the modelling approach on the pandemic due to the spreading of the novel COVID-19 disease and develop a susceptible-infected-removed (SIR) model that provides a theoretical framework to…

Populations and Evolution · Quantitative Biology 2020-08-26 Ian Cooper , Argha Mondal , Chris G. Antonopoulos

Changs in individual behavior often entangles with the dynamic interaction of individuals, which complicates the epidemic process and brings great challenges for the understanding and control of the epidemic. In this work, we consider three…

Physics and Society · Physics 2021-10-27 Bing Wang , Zeyang Xie , Yuexing Han

To study the influence of the moving front of the infected interval and the spatial movement of individuals on the spreading or vanishing of infectious disease, we consider a nonlocal SIS (susceptible-infected-susceptible)…

Analysis of PDEs · Mathematics 2023-01-31 Yachun Tong , Inkyung Ahn , Zhigui Lin

One of the popular dynamics on complex networks is the epidemic spreading. An epidemic model describes how infections spread throughout a network. Among the compartmental models used to describe epidemics, the…

Physics and Society · Physics 2011-07-14 Faryad Darabi Sahneh , Caterina Scoglio

The Markovian approach, which assumes exponentially distributed interinfection times, is dominant in epidemic modeling. However, this assumption is unrealistic as an individual's infectiousness depends on its viral load and varies over…

Populations and Evolution · Quantitative Biology 2023-08-02 Qihui Yang , Joan Saldaña , Caterina Scoglio

Using a probability of novel encounter derived from a physical model, we augment the SIR compartmental model for disease spread. Scenarios with the same initial trajectories and identical $R_0$ values can diverge greatly depending on the…

Populations and Evolution · Quantitative Biology 2020-06-15 Peter Cotton

The temporal dynamics of social interactions were shown to influence the spread of disease. Here, we model the conditions of progression and competition for several viral strains, exploring various levels of cross-immunity over temporal…

Physics and Society · Physics 2022-06-14 Alex Abbey , Yuval Shahar , Osnat Mokryn

This paper introduces a new optimal control model to describe and control the dynamics of infectious diseases. In the present model, the average time of isolation (i.e. hospitalization) of infectious population is the main time-dependent…

Optimization and Control · Mathematics 2015-05-06 Robin J. Evans , Musa Mammadov

We consider a family of periodic SEIRS epidemic models with a fairly general incidence rate and it is shown the basic reproduction number determines the global dynamics of the models and it is a threshold parameter for persistence.…

Dynamical Systems · Mathematics 2017-04-05 Eric Ávila-Vales , Erika Rivero-Esquivel , Gerardo García-Almeida

It is essential to understand the dynamics of epidemics in the presence of coexisting pathogens. There are various phenomenon that can effect the dynamics. In this paper, we formulate a mathematical model using different assumptions to…

Populations and Evolution · Quantitative Biology 2021-11-02 S. Ghersheen , V. Kozlov , U. Wennergren

In this work we performed a numerical study of an epidemic model that mimics the endemic state of whooping cough in the pre-vaccine era. We considered a stochastic SIR model on dynamical networks that involve local and global contacts among…

Physics and Society · Physics 2015-06-09 Martin Dottori , Gabriel Fabricius
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