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Efficient sampling in biomolecular simulations is critical for accurately capturing the complex dynamical behaviors of biological systems. Adaptive sampling techniques aim to improve efficiency by focusing computational resources on the…

Biomolecules · Quantitative Biology 2024-10-22 Hassan Nadeem , Diwakar Shukla

The sequential parameter optimization (SPOT) package for R is a toolbox for tuning and understanding simulation and optimization algorithms. Model-based investigations are common approaches in simulation and optimization. Sequential…

Neural and Evolutionary Computing · Computer Science 2010-06-25 Thomas Bartz-Beielstein

This paper considers sequential adaptive estimation of sparse signals under a constraint on the total sensing effort. The advantage of adaptivity in this context is the ability to focus more resources on regions of space where signal…

Methodology · Statistics 2013-04-03 Dennis Wei , Alfred O. Hero

The interAdapt R package is designed to be used by statisticians and clinical investigators to plan randomized trials. It can be used to determine if certain adaptive designs offer tangible benefits compared to standard designs, in the…

Applications · Statistics 2014-06-19 Aaron Fisher , Harris Jaffee , Michael Rosenblum

The R package BNSP provides a unified framework for semiparametric location-scale regression and stochastic search variable selection. The statistical methodology that the package is built upon utilizes basis function expansions to…

Other Statistics · Statistics 2018-10-09 Georgios Papageorgiou

In several applied fields, multimodality assessment is a crucial task as a previous exploratory tool or for determining the suitability of certain distributions. The goal of this paper is to present the utilities of the R package multimode,…

Computation · Statistics 2022-11-21 Jose Ameijeiras-Alonso , Rosa M. Crujeiras , Alberto Rodríguez-Casal

Subsampling is a widely used and effective approach for addressing the computational challenges posed by massive datasets. Substantial progress has been made in developing non-uniform, probability-based subsampling schemes that prioritize…

Methodology · Statistics 2026-05-07 Dingyi Wang , Haiying Wang , Qingpei Hu

This work presents a guide for the use of some of the functions of the multiColl package in R for the detection of near-multicollinearity. The main contribution, in comparison to other existing packages in R or other econometric software,…

Computation · Statistics 2021-07-08 R. Salmerón , C. B. García , J. García

Science and engineering problems subject to uncertainty are frequently both computationally expensive and feature nonsmooth parameter dependence, making standard Monte Carlo too slow, and excluding efficient use of accelerated uncertainty…

Numerical Analysis · Mathematics 2021-10-01 Per Pettersson , Sebastian Krumscheid

We consider the problem of adaptive stratified sampling for Monte Carlo integration of a noisy function, given a finite budget n of noisy evaluations to the function. We tackle in this paper the problem of adapting to the function at the…

Machine Learning · Statistics 2013-03-13 Alexandra Carpentier , Remi Munos

Background: The use of mixed effect models with a specific functional form such as the Sigmoidal Mixed Model and the Piecewise Mixed Model (or Changepoint Mixed Model) with abrupt or smooth random change allows the interpretation of the…

Methodology · Statistics 2024-01-26 Ana W Capuano , Maude Wagner

Calibrating simulation models that take large quantities of multi-dimensional data as input is a hard simulation optimization problem. Existing adaptive sampling strategies offer a methodological solution. However, they may not sufficiently…

Methodology · Statistics 2024-07-17 Pranav Jain , Sara Shashaani , Eunshin Byon

The allocation problem for multivariate stratified random sampling as a problem of stochastic matrix integer mathematical programming is considered. With these aims the asymptotic normality of sample covariance matrices for each strata is…

Statistics Theory · Mathematics 2011-05-18 Jose A. Diaz-Garcia , Rogelio Ramos-Quiroga

'Optimal cutpoints' for binary classification tasks are often established by testing which cutpoint yields the best discrimination, for example the Youden index, in a specific sample. This results in 'optimal' cutpoints that are highly…

Computation · Statistics 2020-02-24 Christian Thiele , Gerrit Hirschfeld

To increase statistical efficiency in a randomized experiment, researchers often use stratification (i.e., blocking) in the design stage. However, conventional practices of stratification fail to exploit valuable information about the…

Methodology · Statistics 2025-10-28 Zikai Li

For the accurate representation and reconstruction of band-limited signals on the sphere, an optimal-dimensionality sampling scheme has been recently proposed which requires the optimal number of samples equal to the number of degrees of…

Information Theory · Computer Science 2017-09-11 Wajeeha Nafees , Zubair Khalid , Rodney A. Kennedy , Jason D. McEwen

The R package micompr implements a procedure for assessing if two or more multivariate samples are drawn from the same distribution. The procedure uses principal component analysis to convert multivariate observations into a set of linearly…

Mathematical Software · Computer Science 2021-05-11 Nuno Fachada , João Rodrigues , Vitor V. Lopes , Rui C. Martins , Agostinho C. Rosa

Conducting research often involves managing multiple disconnected tools for survey design, data collection, response analysis, and report generation, leading to inefficiencies, increased error risks, and challenges in ensuring…

Computation · Statistics 2025-08-11 Clievins Selva

This work presents a guide for the use of some of the functions of the R package "multiColl" for the detection of near multicollinearity. The main contribution, in comparison to other existing packages in R or other econometric software, is…

Computation · Statistics 2019-11-01 Román Salmerón , Catalina García , José García

The family of stable distributions received extensive applications in many fields of studies since it incorporates both the skewness and heavy tails. In this paper, we introduce a package written in the R language called alphastable. The…

Computation · Statistics 2018-09-26 Mahdi Teimouri , Mahdi Torshizi , Adel Mohammadpour , Saralees Nadarajah