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Increasingly large electronic health records (EHRs) provide an opportunity to algorithmically learn medical knowledge. In one prominent example, a causal health knowledge graph could learn relationships between diseases and symptoms and…
Since the emergence of Large Language Models (LLMs), the challenge of effectively leveraging their potential in healthcare has taken center stage. A critical barrier to using LLMs for extracting insights from unstructured clinical notes…
Foundation model, which is pre-trained on broad data and is able to adapt to a wide range of tasks, is advancing healthcare. It promotes the development of healthcare artificial intelligence (AI) models, breaking the contradiction between…
Electronic health records (EHRs) contain a vast amount of high-dimensional multi-modal data that can accurately represent a patient's medical history. Unfortunately, most of this data is either unstructured or semi-structured, rendering it…
Recent advances in deep learning (DL) have prompted the development of high-performing early warning score (EWS) systems, predicting clinical deteriorations such as acute kidney injury, acute myocardial infarction, or circulatory failure.…
Despite the impressive advancements achieved using deep-learning for functional brain activity analysis, the heterogeneity of functional patterns and scarcity of imaging data still pose challenges in tasks such as prediction of future onset…
Large-scale pretraining has transformed modeling of language and other data types, but its potential remains underexplored in healthcare with structured electronic health records (EHRs). We present a novel generative pretraining strategy…
Accurate estimation of healthcare costs is crucial for healthcare systems to plan and effectively negotiate with insurance companies regarding the coverage of patient-care costs. Greater accuracy in estimating healthcare costs would provide…
In the realm of interactive machine-learning systems, the provision of explanations serves as a vital aid in the processes of debugging and enhancing prediction models. However, the extent to which various global model-centric and…
Foundation models, including language models, e.g., GPT, and vision models, e.g., CLIP, have significantly advanced numerous biomedical tasks. Despite these advancements, the high inference latency and the "overthinking" issues in model…
Large language models (LLMs) have shown promise in medical question answering, yet they often overlook the domain-specific expertise that professionals depend on, such as the clinical subject areas (e.g., trauma, airway) and the…
One of the most urgent problems is the overcrowding in emergency departments (EDs), caused by an aging population and rising healthcare costs. Patient dispositions have become more complex as a result of the strain on hospital…
Retaining persons living with HIV (PLWH) in medical care is paramount to preventing new transmissions of the virus and allowing PLWH to live normal and healthy lifespans. Maintaining regular appointments with an HIV provider and taking…
Multimodal Large Language Models (MLLMs) have shown transformative potential in medical applications, yet their performance is hindered by conventional data curation strategies that rely on coarse-grained partitioning by modality or…
Improving the quality of end-of-life care for hospitalized patients is a priority for healthcare organizations. Studies have shown that physicians tend to over-estimate prognoses, which in combination with treatment inertia results in a…
Recent advances in large language models have enabled their application to a range of healthcare tasks. However, aligning LLMs with the nuanced demands of medical ethics, especially under complex real world scenarios, remains underexplored.…
Clinical decision-making depends on expert reasoning, which is guided by standardized, evidence-based guidelines. However, translating these guidelines into automated clinical decision support systems risks inaccuracy and importantly, loss…
Polycystic Ovary Syndrome (PCOS) constitutes a significant public health issue affecting 10% of reproductive-aged women, highlighting the critical importance of developing effective diagnostic tools. Previous machine learning and deep…
Objective: Temporal electronic health records (EHRs) can be a wealth of information for secondary uses, such as clinical events prediction or chronic disease management. However, challenges exist for temporal data representation. We…
In this paper, we address the knowledge engineering problems for hypothesis generation motivated by applications that require timely exploration of hypotheses under unreliable observations. We looked at two applications: malware detection…