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We propose a simple and exact method for the Traveling Salesman Problem with Time Windows and Makespan objective (\TSPTW-M) that solves all instances of the classical benchmark with $50$ or more customers in less than ten seconds each.…

Data Structures and Algorithms · Computer Science 2026-03-11 Francisco J. Soulignac

The potential analysis of the capabilities of quantum computing, especially before fault tolerance at scale, is difficult due to the variety of existing hardware technologies with a wide spread of maturity. Not only the result of…

Quantum Physics · Physics 2025-07-23 Amine Bentellis , Benedikt Poggel , Jeanette Miriam Lorenz

The Quadratic Unconstrained Binary Optimization (QUBO) modeling and solution framework is a requirement for quantum and digital annealers. However optimality for QUBO problems of any practical size is extremely difficult to achieve. In…

Artificial Intelligence · Computer Science 2021-05-13 Amit Verma , Mark Lewis

With the development of quantum computing, the use of quantum algorithms to solve combinatorial optimization problems on quantum computers has become a major research focus. The Quadratic Unconstrained Binary Optimization (QUBO) model…

Computational Engineering, Finance, and Science · Computer Science 2025-04-10 Haoqian Pan , Changhong Lu

This paper addresses the problem of energy-efficient and safe routing of last-mile electric freight vehicles. With the rising environmental footprint of the transportation sector and the growing popularity of E-Commerce, freight companies…

Optimization and Control · Mathematics 2024-09-24 Prateek Agarwal , Debojjal Bagchi , Tarun Rambha , Venktesh Pandey

Quantum computing is developing fast. Real world applications are within reach in the coming years. One of the most promising areas is combinatorial optimisation, where the Quadratic Unconstrained Binary Optimisation (QUBO) problem…

Quantum Physics · Physics 2020-07-06 Frank Phillipson , Irina Chiscop

Effective epidemic control is crucial for mitigating the spread of infectious diseases, particularly when pharmaceutical interventions such as vaccines or treatments are limited. Non-pharmaceutical strategies, including mobility…

Physics and Society · Physics 2025-12-03 Deborah Volpe , Giacomo Orlandi , Mattia Boggio , Carlo Novara , Lorenzo Zino , Giovanna Turvani

Quadratic unconstrained binary optimization (QUBO) is the mathematical formalism for phrasing and solving a class of optimization problems that are combinatorial in nature. Due to their natural equivalence with the two dimensional Ising…

We extend variational quantum optimization algorithms for Quadratic Unconstrained Binary Optimization problems to the class of Mixed Binary Optimization problems. This allows us to combine binary decision variables with continuous decision…

Quantum Physics · Physics 2021-09-13 Lee Braine , Daniel J. Egger , Jennifer Glick , Stefan Woerner

In this thesis I discuss combinatorial optimization problems, from the statistical physics perspective. The starting point are the motivations which brought physicists together with computer scientists and mathematicians to work on this…

Disordered Systems and Neural Networks · Physics 2020-01-13 Andrea Di Gioacchino

In this paper we study the viability of solving the Chinese Postman Problem, a graph routing optimization problem, and many of its variants on a quantum annealing device. Routing problem variants considered include graph type, directionally…

Quantum Physics · Physics 2022-08-18 Joel E. Pion , Christian F. A. Negre , Susan M. Mniszewski

Current world trade is based and supported in a strong and healthy supply chain, where logistics play a key role in producing and providing key assets and goods to keep societies and economies going. Current geopolitical and sanitary…

Quantum Physics · Physics 2023-01-19 Juan Francisco Ariño Sales , Raúl Andres Palacios Araos

In this paper we focus on the unconstrained binary quadratic optimization model, maximize x^t Qx, x binary, and consider the problem of identifying optimal solutions that are robust with respect to perturbations in the Q matrix.. We are…

Artificial Intelligence · Computer Science 2017-09-25 Mark Lewis , Gary Kochenberger , John Metcalfe

We present a classical algorithm to find approximate solutions to instances of quadratic unconstrained binary optimisation. The algorithm can be seen as an analogue of quantum annealing under the restriction of a product state space, where…

Quantum Physics · Physics 2023-02-14 Joseph Bowles , Alexandre Dauphin , Patrick Huembeli , José Martinez , Antonio Acín

Combinatorial optimization problems are one of the target applications of current quantum technology, mainly because of their industrial relevance, the difficulty of solving large instances of them classically, and their equivalence to…

Quantum Physics · Physics 2024-06-10 J. A. Montanez-Barrera , Pim van den Heuvel , Dennis Willsch , Kristel Michielsen

Quadratic Unconstrained Binary Optimization (QUBO) is a broad class of optimization problems with many practical applications. To solve its hard instances in an exact way, known classical algorithms require exponential time and several…

Quantum Physics · Physics 2021-01-21 Gian Giacomo Guerreschi

We propose a new method for solving binary optimization problems under inequality constraints using a quantum annealer. To deal with inequality constraints, we often use slack variables, as in previous approaches. When we use slack…

Quantum Physics · Physics 2020-12-14 Kouki Yonaga , Masamichi J. Miyama , Masayuki Ohzeki

Several combinatorial optimization problems can be solved with NISQ devices once that a corresponding quadratic unconstrained binary optimization (QUBO) form is derived. The aim of this work is to drastically reduce the variables needed for…

Quantum Physics · Physics 2026-02-25 Dario De Santis , Salvatore Tirone , Stefano Marmi , Vittorio Giovannetti

Next-day delivery logistics services are redefining the industry by increasingly focusing on customer service. A challenge each logistics service provider faces is to jointly optimize time window assignment and vehicle routing for such…

Optimization and Control · Mathematics 2025-01-27 Sifa Celik , Layla Martin , Albert H. Schrotenboer , Tom Van Woensel

Quantum annealers are suited to solve several logistic optimization problems expressed in the QUBO formulation. However, the solutions proposed by the quantum annealers are generally not optimal, as thermal noise and other disturbing…

Quantum Physics · Physics 2024-05-21 Claudio Sanavio , Edoardo Tignone , Elisa Ercolessi