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Alan Turing's work in Morphogenesis has received wide attention during the past 60 years. The central idea behind his theory is that two chemically interacting diffusible substances are able to generate stable spatial patterns, provided…
Despite having advanced a reaction-diffusion model of ODE's in his 1952 paper on morphogenesis, reflecting his interest in mathematical biology, Alan Turing has never been considered to have approached a definition of Cellular Automata.…
Accurate and robust spatial orders are ubiquitous in living systems. In 1952, Alan Turing proposed an elegant mechanism for pattern formation based on spontaneous breaking of the spatial translational symmetry in the underlying…
We comment on Alan Turing's celebrated paper "The Chemical Basis of Morphogenesis" published in 1952 in the "Philosophical Transactions of the Royal Society of London". It is a typical example of a pioneering and inspired work in the domain…
Reaction-diffusion (Turing) systems are fundamental to the formation of spatial patterns in nature and engineering. These systems are governed by a set of non-linear partial differential equations containing parameters that determine the…
Symmetry-breaking instabilities play an important role in understanding the mechanisms underlying the diversity of patterns observed in nature, such as in Turing's reaction--diffusion theory, which connects cellular signalling and transport…
Long after Turing's seminal Reaction-Diffusion (RD) model, the elegance of his fundamental equations alleviated much of the skepticism surrounding pattern formation. Though Turing model is a simplification and an idealization, it is one of…
We hereby develop the theory of Turing instability for reaction-diffusion systems defined on complex networks assuming finite propagation. Extending to networked systems the framework introduced by Cattaneo in the 40's, we remove the…
Pattern formation is ubiquitous in nature and the mechanism widely-accepted to underlay them is based on the Turing instability, predicted by Alan Turing decades ago. This is a non-trivial mechanism that involves nonlinear interaction terms…
In this paper, we introduce a novel approach to study reaction-diffusion systems -- dynamic transition theory approach developed in Ma and Wang 2015. This approach generalizes Turing's classical result (linear stability analysis) on pattern…
Turing patterns in reaction-diffusion (RD) systems have classically been studied only in RD systems which do not explicitly depend on independent variables such as space. In practise, many systems for which Turing patterning is important…
Confirming Turing's theory of morphogens in developmental processes is challenging, and synthetic biology has opened new avenues for testing Turing's predictions. Synthetic mammalian pattern formation has been recently achieved through a…
GTPase molecules are important regulators in cells that continuously run through an activation/deactivation and membrane-attachment/membrane-detachment cycle. Activated GTPase is able to localize in parts of the membranes and to induce cell…
Turing instabilities of reaction-diffusion systems can only arise if the diffusivities of the chemical species are sufficiently different. This threshold is unphysical in most systems with $N=2$ diffusing species, forcing experimental…
Biological, physical, medical, and numerical applications involving membrane problems on different scales are numerous. We propose an extension of the standard Turing theory to the case of two domains separated by a permeable membrane. To…
Turing's theory of pattern formation has been used to describe the formation of self-organised periodic patterns in many biological, chemical and physical systems. However, the use of such models is hindered by our inability to predict, in…
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, although a comprehensive theory of biological pattern formation is still lacking. Here, we propose a minimal model combining tissue mechanics…
In his seminal paper on morphogenesis (1952), Alan Turing demonstrated that different spatio-temporal patterns can arise due to instability of the homogeneous state in reaction-diffusion systems, but at least two species are necessary to…
Modelling diffusion processes in heterogeneous media requires addressing inherent discontinuities across interfaces, where specific conditions are to be met. These challenges fall under the purview of Mathematical Analysis as…
Reaction-diffusion processes across layered media arise in several scientific domains such as pattern-forming E. coli on agar substrates, epidermal-mesenchymal coupling in development, and symmetry-breaking in cell polarisation. We develop…