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Cluster analysis of biological samples using gene expression measurements is a common task which aids the discovery of heterogeneous biological sub-populations having distinct mRNA profiles. Several model-based clustering algorithms have…

Methodology · Statistics 2012-01-30 Alberto Cozzini , Ajay Jasra , Giovanni Montana

In computational mechanics, multiple models are often present to describe a physical system. While Bayesian model selection is a helpful tool to compare these models using measurement data, it requires the computationally expensive…

Computation · Statistics 2025-04-14 Subhayan De , Reza Farzad , Patrick T. Brewick , Erik A. Johnson , Steven F. Wojtkiewicz

Recently, a multi-channel self-reset analog-to-digital converter (ADC) system with complex-valued moduli has been proposed. This system enables the recovery of high dynamic range complex-valued bandlimited signals at low sampling rates via…

Signal Processing · Electrical Eng. & Systems 2025-08-08 Xiaoping Li , Shiyang Sun , Qunying Liao , Xiang-Gen Xia

We introduce the conditional Maximum Composite Likelihood (MCL) estimation method for the stochastic factor ordered Probit model of credit rating transitions of firms. This model is recommended for internal credit risk assessment procedures…

Econometrics · Economics 2023-11-14 Antoine Djogbenou , Christian Gouriéroux , Joann Jasiak , Maygol Bandehali

Likelihood ratios (LRs), which are commonly used for probabilistic data processing, are often estimated based on the frequency counts of individual elements obtained from samples. In natural language processing, an element can be a…

Computation and Language · Computer Science 2021-10-05 Masato Kikuchi , Kento Kawakami , Kazuho Watanabe , Mitsuo Yoshida , Kyoji Umemura

Markov chain Monte Carlo (MCMC) produces a correlated sample for estimating expectations with respect to a target distribution. A fundamental question is when should sampling stop so that we have good estimates of the desired quantities?…

Statistics Theory · Mathematics 2017-10-02 Dootika Vats , James M. Flegal , Galin L. Jones

Partially recorded data are frequently encountered in many applications and usually clustered by first removing incomplete cases or features with missing values, or by imputing missing values, followed by application of a clustering…

Methodology · Statistics 2021-10-20 Emily M. Goren , Ranjan Maitra

One important problem in microbiome analysis is to identify the bacterial taxa that are associated with a response, where the microbiome data are summarized as the composition of the bacterial taxa at different taxonomic levels. This paper…

Applications · Statistics 2016-03-04 Pixu Shi , Anru Zhang , Hongzhe Li

Confounding is a significant obstacle to unbiased estimation of causal effects from observational data. For settings with high-dimensional covariates -- such as text data, genomics, or the behavioral social sciences -- researchers have…

Artificial Intelligence · Computer Science 2024-02-01 Katherine A. Keith , Sergey Feldman , David Jurgens , Jonathan Bragg , Rohit Bhattacharya

Clustering attempts to partition data instances into several distinctive groups, while the similarities among data belonging to the common partition can be principally reserved. Furthermore, incomplete data frequently occurs in many…

Machine Learning · Computer Science 2022-08-30 Miao Cheng , Xinge You

Several interesting generative learning algorithms involve a complex probability distribution over many random variables, involving intractable normalization constants or latent variable normalization. Some of them may even not have an…

Machine Learning · Computer Science 2014-05-13 Yoshua Bengio , Li Yao , Kyunghyun Cho

One-bit quantization has garnered significant attention in recent years for various signal processing and communication applications. Estimating model parameters from one bit quantized data can be challenging, particularly when the…

Signal Processing · Electrical Eng. & Systems 2025-04-01 Nadav E. Rosenthal , Joseph Tabrikian

CUR matrix decomposition is a randomized algorithm that can efficiently compute the low rank approximation for a given rectangle matrix. One limitation with the existing CUR algorithms is that they require an access to the full matrix A for…

Machine Learning · Computer Science 2014-03-25 Rong Jin , Shenghuo Zhu

We develop a central limit theorem (CLT) for a non-parametric estimator of the transition matrices in controlled Markov chains (CMCs) with finite state-action spaces. Our results establish precise conditions on the logging policy under…

Statistics Theory · Mathematics 2026-03-26 Ziwei Su , Imon Banerjee , Diego Klabjan

Reliably characterizing the full conditional distribution of a multivariate response variable given a set of covariates is crucial for trustworthy decision-making. However, misspecified or miscalibrated multivariate models may yield a poor…

Machine Learning · Computer Science 2025-10-27 Victor Dheur , Souhaib Ben Taieb

Contrastive Representation Learning (CRL) has achieved strong empirical success in multiple machine learning disciplines, yet its theoretical sample complexity remains poorly understood. Existing analyses usually assume that input tuples…

Machine Learning · Statistics 2026-05-29 Nong Minh Hieu , Antoine Ledent

A key challenge in differential abundance analysis of microbial samples is that the counts for each sample are compositional, resulting in biased comparisons of the absolute abundance across study groups. Normalization-based differential…

Genomics · Quantitative Biology 2024-11-26 Dylan Clark-Boucher , Brent A Coull , Harrison T Reeder , Fenglei Wang , Qi Sun , Jacqueline R Starr , Kyu Ha Lee

Supervised learning with large-scale data usually leads to complex optimization problems, especially for classification tasks with multiple classes. Stochastic subgradient methods can enable efficient learning with a large number of samples…

Machine Learning · Computer Science 2025-11-25 Kartheek Bondugula , Santiago Mazuelas , Aritz Pérez

Multiple outcomes, both continuous and discrete, are routinely gathered on subjects in longitudinal studies and during routine clinical follow-up in general. To motivate our work, we consider a longitudinal study on patients with primary…

Applications · Statistics 2013-04-17 Arnošt Komárek , Lenka Komárková

Microbiome research has immense potential for unlocking insights into human health and disease. A common goal in human microbiome research is identifying subgroups of individuals with similar microbial composition that may be linked to…

Methodology · Statistics 2025-08-21 Suppapat Korsurat , Matthew D. Koslovsky