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In this paper we propose a workflow to detect and track mitotic cells in time-lapse microscopy image sequences. In order to avoid the requirement for cell lines expressing fluorescent markers and the associated phototoxicity, phase contrast…

Creating meaningful art is often viewed as a uniquely human endeavor. A human artist needs a combination of unique skills, understanding, and genuine intention to create artworks that evoke deep feelings and emotions. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2022-02-25 Konstantin Dobler , Florian Hübscher , Jan Westphal , Alejandro Sierra-Múnera , Gerard de Melo , Ralf Krestel

Analyzing microscopy images to extract biological object properties (e.g., their morphological organization, temporal dynamics, and population density) is fundamental to various biomedical research. Yet conducting this manually is costly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Xiaofei Hui , Haoxuan Qu , Hossein Rahmani , Shuohong Wang , Jeff W. Lichtman , Jun Liu

Live cell culture is crucial in biomedical studies for analyzing cell properties and dynamics in vitro. This study focuses on segmenting unstained live cells imaged with bright-field microscopy. While many segmentation approaches exist for…

Quantitative Methods · Quantitative Biology 2025-08-26 Surajit Das , Gourav Roy , Pavel Zun

Time Varying Functional Connectivity (TVFC) investigates how the interactions among brain regions vary over the course of an fMRI experiment. The transitions between different individual connectivity states can be modulated by changes in…

Multiscale and inhomogeneous molecular systems are challenging topics in the field of molecular simulation. In particular, modeling biological systems in the context of multiscale simulations and exploring material properties are driving a…

Computational Physics · Physics 2017-12-06 Horacio V. Guzman , Christoph Junghans , Kurt Kremer , Torsten Stuehn

In this work, we introduce a new approach for face stylization. Despite existing methods achieving impressive results in this task, there is still room for improvement in generating high-quality artistic faces with diverse styles and…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Mengtian Li , Yi Dong , Minxuan Lin , Haibin Huang , Pengfei Wan , Chongyang Ma

In this paper, we aim to synthesize cell microscopy images under different molecular interventions, motivated by practical applications to drug development. Building on the recent success of graph neural networks for learning molecular…

Biomolecules · Quantitative Biology 2020-06-16 Karren Yang , Samuel Goldman , Wengong Jin , Alex Lu , Regina Barzilay , Tommi Jaakkola , Caroline Uhler

This paper reported a bespoke adder-based deep learning network for time-domain fluorescence lifetime imaging (FLIM). By leveraging the l1-norm extraction method, we propose a 1-D Fluorescence Lifetime AdderNet (FLAN) without…

Signal Processing · Electrical Eng. & Systems 2022-09-13 Zhenya Zang , Dong Xiao , Quan Wang , Ziao Jiao , Chen Yu , David Day-Uei Li

Unconditional human image generation is an important task in vision and graphics, which enables various applications in the creative industry. Existing studies in this field mainly focus on "network engineering" such as designing new…

Computer Vision and Pattern Recognition · Computer Science 2022-04-26 Jianglin Fu , Shikai Li , Yuming Jiang , Kwan-Yee Lin , Chen Qian , Chen Change Loy , Wayne Wu , Ziwei Liu

Generative Adversarial Networks (GAN) have been widely investigated for image synthesis based on their powerful representation learning ability. In this work, we explore the StyleGAN and its application of synthetic food image generation.…

Computer Vision and Pattern Recognition · Computer Science 2023-03-17 Wenjin Fu , Yue Han , Jiangpeng He , Sriram Baireddy , Mridul Gupta , Fengqing Zhu

Imbalanced image datasets are commonly available in the domain of biomedical image analysis. Biomedical images contain diversified features that are significant in predicting targeted diseases. Generative Adversarial Networks (GANs) are…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Muhammad Muneeb Saad , Mubashir Husain Rehmani , Ruairi O'Reilly

Building a virtual cell capable of accurately simulating cellular behaviors in silico has long been a dream in computational biology. We introduce CellFlux, an image-generative model that simulates cellular morphology changes induced by…

Flow-matching generative models are increasingly used to simulate cell responses to biological perturbations. However, the design space for building such models is large and underexplored. We systematically analyse the design space of flow…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Charles Jones , Emmanuel Noutahi , Jason Hartford , Cian Eastwood

Growth patterns generated by filamentous organisms (e.g. actinomycetes and fungi) involve spatial and temporal dynamics at different length scales. Several mathematical models have been proposed in the last thirty years to address these…

Populations and Evolution · Quantitative Biology 2007-05-23 Michele Bezzi , Andrea Ciliberto

Properly modeling latent image distributions plays an important role in a variety of image-related vision problems. Most exiting approaches aim to formulate this problem as optimization models (e.g., Maximum A Posterior, MAP) with…

Computer Vision and Pattern Recognition · Computer Science 2020-08-26 Risheng Liu , Pan Mu , Jian Chen , Xin Fan , Zhongxuan Luo

Recent advances in generative adversarial networks (GANs) have opened up the possibility of generating high-resolution photo-realistic images that were impossible to produce previously. The ability of GANs to sample from high-dimensional…

Computer Vision and Pattern Recognition · Computer Science 2021-10-11 Arthur Conmy , Subhadip Mukherjee , Carola-Bibiane Schönlieb

We report the development and detailed calibration of a multiphoton fluorescence lifetime imaging system (FLIM) using a streak camera. The present system is versatile with high spatial (0.2 micron) and temporal (50 psec) resolution and…

Quantitative Methods · Quantitative Biology 2009-11-10 R. V. Krishnan , H. Saitoh , H. Terada , V. E. Centonze , B. Herman

In this paper we introduce StyleWaveGAN, a style-based drum sound generator that is a variation of StyleGAN, a state-of-the-art image generator. By conditioning StyleWaveGAN on both the type of drum and several audio descriptors, we are…

Sound · Computer Science 2022-08-29 Antoine Lavault , Axel Roebel , Matthieu Voiry

Time series synthesis is an effective approach to ensuring the secure circulation of time series data. Existing time series synthesis methods typically perform temporal modeling based on random sequences to generate target sequences, which…

Machine Learning · Computer Science 2025-09-01 Xuan Hou , Shuhan Liu , Zhaohui Peng , Yaohui Chu , Yue Zhang , Yining Wang
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