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High-throughput sequencing (HTS) technologies have revolutionized the field of genomics, enabling rapid and cost-effective genome analysis for various applications. However, the increasing volume of genomic data generated by HTS…

Hardware Architecture · Computer Science 2023-06-01 Onur Mutlu , Can Firtina

In high-dimensional vector spaces, Approximate Nearest Neighbor Search (ANNS) is a key component in database and artificial intelligence infrastructures. Graph-based methods, particularly HNSW, have emerged as leading solutions among…

Databases · Computer Science 2025-02-26 Mengzhao Wang , Haotian Wu , Xiangyu Ke , Yunjun Gao , Yifan Zhu , Wenchao Zhou

Heterogeneous graph neural networks (HGNNs) were proposed for representation learning on structural data with multiple types of nodes and edges. To deal with the performance degradation issue when HGNNs become deep, researchers combine…

Machine Learning · Computer Science 2023-11-27 Xinyu Fu , Irwin King

Modern analytical pipelines routinely deploy multiple deep learning and retrieval models that rely on approximate nearest-neighbor (ANN) indexes to support efficient similarity-based search. While many state-of-the-art ANN-indexes are…

Information Retrieval · Computer Science 2025-07-30 Omar Shahbaz Khan , Gylfi Þór Guðmundsson , Björn Þór Jónsson

Recent emergence of next-generation DNA sequencing technology has enabled acquisition of genetic information at unprecedented scales. In order to determine the genetic blueprint of an organism, sequencing platforms typically employ…

Genomics · Quantitative Biology 2015-06-19 Xiaohu Shen , Manohar Shamaiah , Haris Vikalo

Packet classification is a vital and complicated task as the processing of packets should be done at a specified line speed. In order to classify a packet as belonging to a particular flow or set of flows, network nodes must perform a…

Networking and Internet Architecture · Computer Science 2014-04-08 Pallavi. V. S , Dr. Rukmani Devi. D

We present SuperKMeans: a k-means variant designed for clustering collections of high-dimensional vector embeddings. SuperKMeans' clustering is up to 7x faster than FAISS and Scikit-Learn on modern CPUs and up to 4x faster than cuVS on GPUs…

Machine Learning · Computer Science 2026-03-23 Leonardo Kuffo , Sven Hepkema , Peter Boncz

Convolutional Neural Networks (CNN) have gained great success in many artificial intelligence tasks. However, finding a good set of hyperparameters for a CNN remains a challenging task. It usually takes an expert with deep knowledge, and…

Neural and Evolutionary Computing · Computer Science 2020-06-25 Xueli Xiao , Ming Yan , Sunitha Basodi , Chunyan Ji , Yi Pan

Designing RNA molecules has garnered recent interest in medicine, synthetic biology, biotechnology and bioinformatics since many functional RNA molecules were shown to be involved in regulatory processes for transcription, epigenetics and…

Machine Learning · Computer Science 2019-04-15 Frederic Runge , Danny Stoll , Stefan Falkner , Frank Hutter

Hyperdimensional Computing (HDC) is a bio-inspired computing framework that has gained increasing attention, especially as a more efficient approach to machine learning (ML). This work introduces the \name{} compiler, the first open-source…

Machine Learning · Computer Science 2023-04-26 Pere Vergés , Mike Heddes , Igor Nunes , Tony Givargis , Alexandru Nicolau

Despite the success of recent Neural Architecture Search (NAS) methods on various tasks which have shown to output networks that largely outperform human-designed networks, conventional NAS methods have mostly tackled the optimization of…

Machine Learning · Computer Science 2021-07-05 Hayeon Lee , Eunyoung Hyung , Sung Ju Hwang

Neural graphics primitives, parameterized by fully connected neural networks, can be costly to train and evaluate. We reduce this cost with a versatile new input encoding that permits the use of a smaller network without sacrificing…

Computer Vision and Pattern Recognition · Computer Science 2022-05-05 Thomas Müller , Alex Evans , Christoph Schied , Alexander Keller

The biochemical processes underlying DNA data storage, including synthesis, amplification, and sequencing, are inherently noisy. Consequently, base-level insertion, deletion, and substitution (IDS) errors, as well as sequence-level…

Information Theory · Computer Science 2026-03-17 Ramy Khabbaz , Jérémy Mateos , Marc Antonini , Serge Kas Hanna

Modern deep learning models capture the semantics of complex data by transforming them into high-dimensional embedding vectors. Emerging applications, such as retrieval-augmented generation, use approximate nearest neighbor (ANN) search in…

Databases · Computer Science 2025-10-01 Guoyu Hu , Shaofeng Cai , Tien Tuan Anh Dinh , Zhongle Xie , Cong Yue , Gang Chen , Beng Chin Ooi

DNA sequencing is revolutionising the field of medicine. DNA sequencers, the machines which perform DNA sequencing, have evolved from the size of a fridge to that of a mobile phone over the last two decades. The cost of sequencing a human…

Genomics · Quantitative Biology 2021-01-14 Hasindu Gamaarachchi

Energy-efficient medical data classification is essential for modern disease screening, particularly in home and field healthcare where embedded devices are prevalent. While deep learning models achieve state-of-the-art accuracy, their…

Machine Learning · Computer Science 2026-03-24 Jianglan Wei , Zhenyu Zhang , Pengcheng Wang , Mingjie Zeng , Zhigang Zeng

Gradient based meta-learning methods are prone to overfit on the meta-training set, and this behaviour is more prominent with large and complex networks. Moreover, large networks restrict the application of meta-learning models on low-power…

Machine Learning · Computer Science 2022-06-06 Arnav Chavan , Rishabh Tiwari , Udbhav Bamba , Deepak K. Gupta

Metagenome assembly is the process of transforming a set of short, overlapping, and potentially erroneous DNA segments from environmental samples into the accurate representation of the underlying microbiomes's genomes. State-of-the-art…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-09-20 Evangelos Georganas , Rob Egan , Steven Hofmeyr , Eugene Goltsman , Bill Arndt , Andrew Tritt , Aydin Buluc , Leonid Oliker , Katherine Yelick

DNA sequencing is the physical/biochemical process of identifying the location of the four bases (Adenine, Guanine, Cytosine, Thymine) in a DNA strand. As semiconductor technology revolutionized computing, modern DNA sequencing technology…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-05-06 S. Karen Khatamifard , Zamshed Chowdhury , Nakul Pande , Meisam Razaviyayn , Chris Kim , Ulya R. Karpuzcu

Training deep learning models and performing hyperparameter tuning can be computationally demanding and time-consuming. Meanwhile, traditional machine learning methods like gradient-boosting algorithms remain the preferred choice for most…

Machine Learning · Computer Science 2024-02-23 David Bonet , Daniel Mas Montserrat , Xavier Giró-i-Nieto , Alexander G. Ioannidis