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Bioinformatics research is characterized by voluminous and incremental datasets and complex data analytics methods. The machine learning methods used in bioinformatics are iterative and parallel. These methods can be scaled to handle big…

Computational Engineering, Finance, and Science · Computer Science 2015-06-17 Hirak Kashyap , Hasin Afzal Ahmed , Nazrul Hoque , Swarup Roy , Dhruba Kumar Bhattacharyya

Researchers in the field of biocomputing have, for many years, successfully "harvested and exploited" the natural world for inspiration in developing systems that are robust, adaptable and capable of generating novel and even "creative"…

Artificial Intelligence · Computer Science 2007-05-23 Jon Timmis , Martyn Amos , Wolfgang Banzhaf , Andy Tyrrell

Nowadays, Cellular Neural Networks (CNN) are practically implemented in parallel, analog computers, showing a fast developing trend. Physicist must be aware that such computers are appropriate for solving in an elegant manner practically…

Disordered Systems and Neural Networks · Physics 2016-02-17 Mária Ercsey-Ravasz , Tamás Roska , Zoltán Néda

If the 20th century was known for the computational revolution, what will the 21st be known for? Perhaps the recent strides in the nascent fields of molecular programming and biological computation will help bring about the 'Coming Era of…

Statistical Mechanics · Physics 2022-03-14 Hannah Amelie Earley

Novel computing hardwares are necessary to keep up with today's increasing demand for data storage and processing power. In this research project, we turn to the brain for inspiration to develop novel computing substrates that are…

Neurons and Cognition · Quantitative Biology 2019-07-05 Kristine Heiney , Vibeke Devold Valderhaug , Ioanna Sandvig , Axel Sandvig , Gunnar Tufte , Hugo Lewi Hammer , Stefano Nichele

In this article, we attempt to make a conceptual bridge between the research in biology, pre-biotic chemistry, biomimetics, and the tools used in organic bioelectronics in terms of materials and devices. The goal is discussing how materials…

Fluid Dynamics · Physics 2025-04-16 Giuseppe De Giorgio , Pasquale D'Angelo , Giuseppe Tarabella , Saksham Sharma

Living systems continuously transform matter and energy through the chemical processes that constitute their metabolism. The overall metabolic rate of an organism correlates positively with its body mass, however both the exact scaling…

Soft Condensed Matter · Physics 2026-03-19 Efe Ilker , Michael Hinczewski , Xingbo Yang , Frank Jülicher

Biological neural networks continue to inspire breakthroughs in neural network performance. And yet, one key area of neural computation that has been under-appreciated and under-investigated is biologically plausible, energy-efficient…

Neural and Evolutionary Computing · Computer Science 2023-03-22 Kai Malcolm , Josue Casco-Rodriguez

Machine learning applications that are implemented with spike-based computation model, e.g., Spiking Neural Network (SNN), have a great potential to lower the energy consumption when they are executed on a neuromorphic hardware. However,…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-05-13 Shihao Song , Adarsha Balaji , Anup Das , Nagarajan Kandasamy , James Shackleford

Neuromorphic Computing (NC) and Spiking Neural Networks (SNNs) in particular are often viewed as the next generation of Neural Networks (NNs). NC is a novel bio-inspired paradigm for energy efficient neural computation, often relying on…

Robotics · Computer Science 2024-09-18 Andreas Ziegler , Karl Vetter , Thomas Gossard , Jonas Tebbe , Sebastian Otte , Andreas Zell

The integration of more renewable energy sources into the power system is presenting system operators with various challenges. At the distribution system level, voltage magnitudes that violate operating limits near large photovoltaic…

Optimization and Control · Mathematics 2022-01-05 Sandro Merkli , Roy S. Smith

High Performance Computing (HPC) aims at providing reasonably fast computing solutions to scientific and real life problems. The advent of multicore architectures is noticeable in the HPC history, because it has brought the underlying…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-07 Claude Tadonki

An astonishingly diverse biomolecular circuitry orchestrates the functioning machinery underlying every living cell. These biomolecules and their circuits have been engineered not only for various industrial applications but also to perform…

Biomolecules · Quantitative Biology 2021-02-15 Sahana Gangadharan , Karthik Raman

Advances in molecular technologies underlie an enormous growth in the size of data sets pertaining to biology and biomedicine. These advances parallel those in the deep learning subfield of machine learning. Components in the differentiable…

Quantitative Methods · Quantitative Biology 2024-06-14 Alex Jihun Lee , Reza Abbasi-Asl

Current computers operate at enormous speeds of ~10^13 bits/s, but their principle of sequential logic operation has remained unchanged since the 1950s. Though our brain is much slower on a per-neuron base (~10^3 firings/s), it is capable…

Emerging Technologies · Computer Science 2015-05-30 Anirban Bandyopadhyay , Ranjit Pati , Satyajit Sahu , Ferdinand Peper , Daisuke Fujita

Most experimental sciences now rely on computing, and biological sciences are no exception. As datasets get bigger, so do the computing costs, making proper optimization of the codes used by scientists increasingly important. Many of the…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-07-21 Igor Sfiligoi , Daniel McDonald , Rob Knight

High-throughput experimental techniques and bioinformatics tools make it possible to obtain reconstructions of the metabolism of microbial species. Combined with mathematical frameworks such as flux balance analysis, which assumes that…

Due to the massive parallel computing capability and outstanding image and signal processing performance, cellular neural network (CNN) is one promising type of non-Boolean computing system that can outperform the traditional digital logic…

Emerging Technologies · Computer Science 2016-09-21 Chenyun Pan , Azad Naeemi

The concept of scalability analysis of numerical parallel applications has been revisited, with the specific goals defined for the performance estimation of research applications. A series of Community Climate Model System (CCSM) numerical…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-11-08 Natalie Perlin , Joel P. Zysman , Ben P. Kirtman

Neuromorphic computing and spiking neural networks aim to leverage biological inspiration to achieve greater energy efficiency and computational power beyond traditional von Neumann architectured machines. In particular, spiking neural…

Neural and Evolutionary Computing · Computer Science 2023-04-17 Nicholas J. Pritchard , Andreas Wicenec , Mohammed Bennamoun , Richard Dodson