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OBJECTIVE: To propose time-to-event estimators that help evaluate incident diagnostic coding and possible upcoding in Medicare as well as introduce an open-source software package that enables more reproducible methods development relevant…

Applications · Statistics 2026-05-21 Oana M. Enache , Sherri Rose

Score-based explainable machine-learning techniques are often used to understand the logic behind black-box models. However, such explanation techniques are often computationally expensive, which limits their application in time-critical…

Machine Learning · Computer Science 2023-08-24 Amr Alkhatib , Henrik Boström , Sofiane Ennadir , Ulf Johansson

Causal inference across multiple data sources offers a promising avenue to enhance the generalizability and replicability of scientific findings. However, data integration methods for time-to-event outcomes, common in biomedical research,…

Methodology · Statistics 2025-05-16 Yi Liu , Alexander W. Levis , Ke Zhu , Shu Yang , Peter B. Gilbert , Larry Han

The individual data collected throughout patient follow-up constitute crucial information for assessing the risk of a clinical event, and eventually for adapting a therapeutic strategy. Joint models and landmark models have been proposed to…

Machine Learning · Statistics 2024-07-17 Anthony Devaux , Robin Genuer , Karine Pérès , Cécile Proust-Lima

Models for predicting the time of a future event are crucial for risk assessment, across a diverse range of applications. Existing time-to-event (survival) models have focused primarily on preserving pairwise ordering of estimated event…

Machine Learning · Statistics 2021-01-14 Paidamoyo Chapfuwa , Chenyang Tao , Lawrence Carin , Ricardo Henao

The integration of high-dimensional genomic data and clinical data into time-to-event prediction models has gained significant attention due to the growing availability of these datasets. Traditionally, a Cox regression model is employed,…

Methodology · Statistics 2025-04-03 Dayasri Ravi , Andreas Groll

Clinical risk prediction models often underperform in real-world settings due to poor calibration, limited transportability, and subgroup disparities. These challenges are amplified in high-dimensional multimodal cancer datasets…

Machine Learning · Computer Science 2026-02-26 Toktam Khatibi

Survival Analysis (SA) constitutes the default method for time-to-event modeling due to its ability to estimate event probabilities of sparsely occurring events over time. In this work, we show how to improve the training and inference of…

Machine Learning · Computer Science 2023-12-12 Chris Solomou

Risk scores are an interpretable and actionable class of machine learning models with applications in medicine, insurance, and risk management. Unlike most computational methods, risk scores are designed to be computed by a human by…

Machine Learning · Computer Science 2026-05-05 Costa Georgantas , Jonas Richiardi

Risk scores are simple classification models that let users make quick risk predictions by adding and subtracting a few small numbers. These models are widely used in medicine and criminal justice, but are difficult to learn from data…

Machine Learning · Statistics 2020-10-21 Berk Ustun , Cynthia Rudin

The instability in the selection of models is a major concern with data sets containing a large number of covariates. This paper deals with variable selection methodology in the case of high-dimensional problems where the response variable…

Applications · Statistics 2012-03-23 Marie Walschaerts , Eve Leconte , Philippe Besse

Many applications involve reasoning about time durations before a critical event happens--also called time-to-event outcomes. When will a customer cancel a subscription, a coma patient wake up, or a convicted criminal reoffend?…

Machine Learning · Statistics 2024-10-03 George H. Chen

Survival analysis, or time-to-event modelling, is a classical statistical problem that has garnered a lot of interest for its practical use in epidemiology, demographics or actuarial sciences. Recent advances on the subject from the point…

Machine Learning · Computer Science 2021-07-28 Guillaume Ausset , Tom Ciffreo , Francois Portier , Stephan Clémençon , Timothée Papin

Survival analysis is widely used as a technique to model time-to-event data when some data is censored, particularly in healthcare for predicting future patient risk. In such settings, survival models must be both accurate and interpretable…

Machine Learning · Computer Science 2024-04-24 Mike Van Ness , Madeleine Udell

Successful application of machine learning models to real-world prediction problems, e.g. financial forecasting and personalized medicine, has proved to be challenging, because such settings require limiting and quantifying the uncertainty…

Machine Learning · Computer Science 2020-09-15 Yao Zhang , William Zame , Mihaela van der Schaar

Survival analysis is a statistical framework for modeling time-to-event data, particularly valuable in healthcare for predicting outcomes like patient discharge or recurrence. This study implements and compares several survival models -…

Analyzing better time series with limited human effort is of interest to academia and industry. Driven by business scenarios, we organized the first Automated Time Series Regression challenge (AutoSeries) for the WSDM Cup 2020. We present…

Machine Learning · Computer Science 2021-12-28 Zhen Xu , Wei-Wei Tu , Isabelle Guyon

The distribution-free method of conformal prediction (Vovk et al, 2005) has gained considerable attention in computer science, machine learning, and statistics. Candes et al. (2023) extended this method to right-censored survival data,…

Methodology · Statistics 2025-06-04 Jing Qin , Jin Piao , Jing Ning , Yu Shen

Synthetically generated data can improve privacy, fairness, and data accessibility; however, it can be challenging in specialized scenarios such as survival analysis. One key challenge in this setting is censoring, i.e., the timing of an…

Machine Learning · Statistics 2025-08-07 Mohd Ashhad , Ricardo Henao

As in many fields of medical research, survival analysis has witnessed a growing interest in the application of deep learning techniques to model complex, high-dimensional, heterogeneous, incomplete, and censored medical data. Current…

Machine Learning · Computer Science 2023-12-25 Patricia A. Apellániz , Juan Parras , Santiago Zazo