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The vast amount of health data has been continuously collected for each patient, providing opportunities to support diverse healthcare predictive tasks such as seizure detection and hospitalization prediction. Existing models are mostly…

Machine Learning · Computer Science 2023-02-16 Chaoqi Yang , M. Brandon Westover , Jimeng Sun

Histopathological images are essential for medical diagnosis and treatment planning, but interpreting them accurately using machine learning can be challenging due to variations in tissue preparation, staining and imaging protocols. Domain…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Vaibhav Khamankar , Sutanu Bera , Saumik Bhattacharya , Debashis Sen , Prabir Kumar Biswas

Background: Image classification can be considered one of the key pillars of medical image analysis. Deep learning (DL) faces challenges that prevent its practical applications despite the remarkable improvement in medical image…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Shahabedin Nabavi , Kian Anvari Hamedani , Mohsen Ebrahimi Moghaddam , Ahmad Ali Abin , Alejandro F. Frangi

Modern deep neural networks struggle to transfer knowledge and generalize across diverse domains when deployed to real-world applications. Currently, domain generalization (DG) is introduced to learn a universal representation from multiple…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Yijun Yang , Shujun Wang , Lei Zhu , Lequan Yu

Diabetic Retinopathy (DR), a leading cause of vision impairment, requires early detection and treatment. Developing robust AI models for DR classification holds substantial potential, but a key challenge is ensuring their generalization in…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Sanoojan Baliah , Fadillah A. Maani , Santosh Sanjeev , Muhammad Haris Khan

Model-agnostic meta-learners aim to acquire meta-learned parameters from similar tasks to adapt to novel tasks from the same distribution with few gradient updates. With the flexibility in the choice of models, those frameworks demonstrate…

Machine Learning · Computer Science 2019-10-31 Risto Vuorio , Shao-Hua Sun , Hexiang Hu , Joseph J. Lim

Multi-Source Domain Generalization (DG) is the task of training on multiple source domains and achieving high classification performance on unseen target domains. Recent methods combine robust features from web-scale pretrained backbones…

Computer Vision and Pattern Recognition · Computer Science 2025-04-23 Piotr Teterwak , Kuniaki Saito , Theodoros Tsiligkaridis , Bryan A. Plummer , Kate Saenko

Deep neural networks (DNN) have demonstrated unprecedented success for medical imaging applications. However, due to the issue of limited dataset availability and the strict legal and ethical requirements for patient privacy protection, the…

Machine Learning · Computer Science 2023-09-19 Chris Xing Tian , Haoliang Li , Yufei Wang , Shiqi Wang

Source-free test-time adaptation for medical image segmentation aims to enhance the adaptability of segmentation models to diverse and previously unseen test sets of the target domain, which contributes to the generalizability and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-19 Yanyu Ye , Zhenxi Zhang , Wei Wei , Chunna Tian

Domain Generalization (DG) aims to generalize a model trained on multiple source domains to an unseen target domain. The source domains always require precise annotations, which can be cumbersome or even infeasible to obtain in practice due…

Computer Vision and Pattern Recognition · Computer Science 2023-04-06 Luojun Lin , Han Xie , Zhishu Sun , Weijie Chen , Wenxi Liu , Yuanlong Yu , Lei Zhang

This work provides a strong baseline for the problem of multi-source multi-target domain adaptation and generalization in medical imaging. Using a diverse collection of ten chest X-ray datasets, we empirically demonstrate the benefits of…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Li Yao , Jordan Prosky , Ben Covington , Kevin Lyman

Recognizing atypical mitotic figures in histopathology images allows physicians to correctly assess tumor aggressiveness. Although machine learning models could be exploited for automatically performing such a task, under domain shift these…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 Gennaro Percannella , Mattia Sarno , Francesco Tortorella , Mario Vento

Segmentation is a crucial analysis task in biomedical imaging. Given the diverse experimental settings in this field, the lack of generalization limits the use of deep learning in practice. Domain adaptation is a promising remedy: it…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Anwai Archit , Constantin Pape

In AI-based histopathology, domain shifts are common and well-studied. However, this research focuses on stain and scanner variations, which do not show the full picture -- shifts may be combinations of other shifts, or "invisible" shifts…

Image and Video Processing · Electrical Eng. & Systems 2023-05-10 Andrew Walker

Generalization is one of the key challenges in the clinical validation and application of deep learning models to medical images. Studies have shown that such models trained on publicly available datasets often do not work well on…

Computer Vision and Pattern Recognition · Computer Science 2020-03-04 Yu Zhang , Gongbo Liang , Nathan Jacobs , Xiaoqin Wang

Medical image segmentation models often struggle to generalize across different domains due to various reasons. Domain Generalization (DG) methods overcome this either through representation learning or data augmentation (DAug). While…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Piyush Tiwary , Kinjawl Bhattacharyya , Prathosh A. P

To segment medical images with distribution shifts, domain generalization (DG) has emerged as a promising setting to train models on source domains that can generalize to unseen target domains. Existing DG methods are mainly based on CNN or…

Computer Vision and Pattern Recognition · Computer Science 2025-04-25 Zihan Cheng , Jintao Guo , Jian Zhang , Lei Qi , Luping Zhou , Yinghuan Shi , Yang Gao

The annotation scarcity of medical image segmentation poses challenges in collecting sufficient training data for deep learning models. Specifically, models trained on limited data may not generalize well to other unseen data domains,…

Image and Video Processing · Electrical Eng. & Systems 2023-07-19 Heng Li , Haojin Li , Wei Zhao , Huazhu Fu , Xiuyun Su , Yan Hu , Jiang Liu

Domain Generalization (DG) is a fundamental challenge for machine learning models, which aims to improve model generalization on various domains. Previous methods focus on generating domain invariant features from various source domains.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Daoan Zhang , Mingkai Chen , Chenming Li , Lingyun Huang , Jianguo Zhang

The deep learning technique has been shown to be effectively addressed several image analysis tasks in the computer-aided diagnosis scheme for mammography. The training of an efficacious deep learning model requires large data with diverse…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Zheren Li , Zhiming Cui , Lichi Zhang , Sheng Wang , Chenjin Lei , Xi Ouyang , Dongdong Chen , Xiangyu Zhao , Yajia Gu , Zaiyi Liu , Chunling Liu , Dinggang Shen , Jie-Zhi Cheng