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There is growing consensus among neuroscientists that neural circuits critical for survival are the result of genomic decompression processes. We introduce SynaptoGen, a novel computational framework--member of the Connectome Models…

Neural and Evolutionary Computing · Computer Science 2025-09-09 Tommaso Boccato , Matteo Ferrante , Nicola Toschi

The brain can efficiently learn a wide range of tasks, motivating the search for biologically inspired learning rules for improving current artificial intelligence technology. Most biological models are composed of point neurons, and cannot…

Neurons and Cognition · Quantitative Biology 2026-04-13 Cristiano Capone , Cosimo Lupo , Paolo Muratore , Pier Stanislao Paolucci

Interfacing artificial functional materials and living neuronal tissues is at the forefront of bio-nano-technology. Attempts have been so far based onto microscale processing of metals and inorganic semiconductors as electrodes or…

This paper gives an overview of recent progress in the brain inspired computing field with a focus on implementation using emerging memories as electronic synapses. Design considerations and challenges such as requirements and design…

Neural and Evolutionary Computing · Computer Science 2016-05-09 Sukru Burc Eryilmaz , Duygu Kuzum , Shimeng Yu , H. -S. Philip Wong

Magnetic skyrmions are promising candidates for next-generation information carriers, owing to their small size, topological stability, and ultralow depinning current density. A wide variety of skyrmionic device concepts and prototypes have…

Emerging Technologies · Computer Science 2017-02-21 Yangqi Huang , Wang Kang , Xichao Zhang , Yan Zhou , Weisheng Zhao

Dendritic spines are key structural components of excitatory synapses in the brain. Given the size of dendritic spines provides a proxy for synaptic efficacy, their detection and tracking across time is important for studies of the neural…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Pamela Osuna-Vargas , Altug Kamacioglu , Dominik F. Aschauer , Petros E. Vlachos , Sercan Alipek , Jochen Triesch , Simon Rumpel , Matthias Kaschube

Neuromorphic architectures offer great promise for achieving computation capacities beyond conventional Von Neumann machines. The essential elements for achieving this vision are highly scalable synaptic mimics that do not undermine…

Emerging Technologies · Computer Science 2015-07-09 Radu Berdan , Eleni Vasilaki , Ali Khiat , Giacomo Indiveri , Alexandru Serb , Themistoklis Prodromakis

Inspired by the brain, we present a physical alternative to traditional digital neural networks -- a microfluidic network in which nodes are connected by conical, electrolyte-filled channels acting as memristive iontronic synapses. Their…

Soft Condensed Matter · Physics 2025-11-07 Monica Conte , René van Roij , Marjolein Dijkstra

In many normative theories of synaptic plasticity, weight updates implicitly depend on the chosen parametrization of the weights. This problem relates, for example, to neuronal morphology: synapses which are functionally equivalent in terms…

Neurons and Cognition · Quantitative Biology 2022-02-25 Elena Kreutzer , Walter M. Senn , Mihai A. Petrovici

Brain-inspired computing proposes a set of algorithmic principles that hold promise for advancing artificial intelligence. They endow systems with self learning capabilities, efficient energy usage, and high storage capacity. A core concept…

Neural and Evolutionary Computing · Computer Science 2022-12-01 Younes Bouhadjar , Sebastian Siegel , Tom Tetzlaff , Markus Diesmann , Rainer Waser , Dirk J. Wouters

The stringent memory and power constraints required in edge-computing sensory-processing applications have made event-driven neuromorphic systems a promising technology. On-chip online learning provides such systems the ability to learn the…

Emerging Technologies · Computer Science 2022-01-26 Matteo Cartiglia , Arianna Rubino , Shyam Narayanan , Charlotte Frenkel , Germain Haessig , Giacomo Indiveri , Melika Payvand

Learning with physical systems is an emerging paradigm that seeks to harness the intrinsic nonlinear dynamics of physical substrates for learning. The impetus for a paradigm shift in how hardware is used for computational intelligence stems…

Disordered Systems and Neural Networks · Physics 2026-04-28 Francesco Caravelli , Gianluca Milano , Adam Z. Stieg , Carlo Ricciardi , Simon Anthony Brown , Zdenka Kuncic

The bottom two layers of a neuromorphic architecture are designed and shown to be capable of online clustering and supervised classification. An active spiking dendrite model is used, and a single dendritic segment performs essentially the…

Neural and Evolutionary Computing · Computer Science 2023-10-30 J. E. Smith

The continuous effort in making artificial neural networks more alike to human brain calls for the hardware elements to implement biological synapse-like functionalities. The recent experimental demonstration of ferroelectric-like FETs…

Biological plastic neural networks are systems of extraordinary computational capabilities shaped by evolution, development, and lifetime learning. The interplay of these elements leads to the emergence of adaptive behavior and…

Neural and Evolutionary Computing · Computer Science 2018-08-09 Andrea Soltoggio , Kenneth O. Stanley , Sebastian Risi

The computational efficiency of the human brain is believed to stem from the parallel information processing capability of neurons with integrated storage in synaptic interconnections programmed by local spike triggered learning rules such…

Emerging Technologies · Computer Science 2020-03-17 S. R. Nandakumar , Bipin Rajendran

Compact models of memristors are essential for simulating large-scale neuromorphic systems, yet they often do not include description of complex dynamics like volatile relaxation and synaptic plasticity. We introduce a modular,…

Memristors can mimic the functions of biological synapse, where it can simultaneously store the synaptic weight and modulate the transmitted signal. Here, we report Nb/Nb2O5/Pt based memristors with bipolar resistive switching, exhibiting…

Applied Physics · Physics 2019-10-02 Sweety Deswal , Ashok Kumar , Ajeet Kumar

Probabilistic bits (p-bits) are stochastic hardware elements whose output probability can be tuned by an input bias, offering a route to energy-efficient architectures that exploit, rather than suppress, fluctuations. Here we report p-bit…

Cue integration, the combination of different sources of information to reduce uncertainty, is a fundamental computational principle of brain function. Starting from a normative model we show that the dynamics of multi-compartment neurons…

Neurons and Cognition · Quantitative Biology 2020-06-29 Jakob Jordan , João Sacramento , Mihai A. Petrovici , Walter Senn