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The aim of the systematic review was to assess recently published studies on diagnostic test accuracy of glioblastoma treatment response monitoring biomarkers in adults, developed through machine learning (ML). Articles were searched for…

Solving the inverse problem is the key step in evaluating the capacity of a physical model to describe real phenomena. In medical image computing, it aligns with the classical theme of image-based model personalization. Traditionally, a…

Multimodal MRI is essential for brain tumor segmentation, yet missing modalities in clinical practice cause existing methods to exhibit >40% performance variance across modality combinations, rendering them clinically unreliable. We propose…

Image and Video Processing · Electrical Eng. & Systems 2026-01-28 Chengxiang Guo , Jian Wang , Junhua Fei , Xiao Li , Chunling Chen , Yun Jin

Gliomas are among the most aggressive cancers, characterized by high mortality rates and complex diagnostic processes. Existing studies on glioma diagnosis and classification often describe issues such as high variability in imaging data,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Md. Abdur Rahman , Mohaimenul Azam Khan Raiaan , Arefin Ittesafun Abian , Yan Zhang , Mirjam Jonkman , Sami Azam

Predicting the spatio-temporal progression of brain tumors is essential for guiding clinical decisions in neuro-oncology. We propose a hybrid mechanistic learning framework that combines a mathematical tumor growth model with a guided…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Daria Laslo , Efthymios Georgiou , Marius George Linguraru , Andreas Rauschecker , Sabine Muller , Catherine R. Jutzeler , Sarah Bruningk

The ability to estimate how a tumor might evolve in the future could have tremendous clinical benefits, from improved treatment decisions to better dose distribution in radiation therapy. Recent work has approached the glioma growth…

Gliomas are the most common malignant brain tumors in adults and are among the most lethal. Despite aggressive treatment, the median survival rate is less than 15 months. Accurate multiparametric MRI (mpMRI) tumor segmentation is critical…

Brain tumors are one of the most common diseases that lead to early death if not diagnosed at an early stage. Traditional diagnostic approaches are extremely time-consuming and prone to errors. In this context, computer vision-based…

Computer Vision and Pattern Recognition · Computer Science 2024-07-01 Niful Islam , Mohaiminul Islam Bhuiyan , Jarin Tasnim Raya , Nur Shazwani Kamarudin , Khan Md Hasib , M. F. Mridha , Dewan Md. Farid

The brain is a complex organ controlling cognitive process and physical functions. Tumors in the brain are accelerated cell growths affecting the normal function and processes in the brain. MRI scans provides detailed images of the body…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Miriam Zulema Jacobo , Jose Mejia

In this work, we develop a stochastic multiscale model for glioma growth and invasion in the brain, incorporating the effects of therapeutic interventions. The model accounts for tumor cell migration influenced by brain tissue heterogeneity…

Cell Behavior · Quantitative Biology 2026-02-10 Martina Conte , Sandesh Hiremath , Christina Surulescu

Brain Tumors are abnormal mass of clustered cells penetrating regions of brain. Their timely identification and classification help doctors to provide appropriate treatment. However, Classifi-cation of Brain Tumors is quite intricate…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Aman Verma , Vibhav Prakash Singh

A brain tumor, whether benign or malignant, can potentially be life threatening and requires painstaking efforts in order to identify the type, origin and location, let alone cure one. Manual segmentation by medical specialists can be…

Image and Video Processing · Electrical Eng. & Systems 2023-05-02 Ayan Gupta , Mayank Dixit , Vipul Kumar Mishra , Attulya Singh , Atul Dayal

Structural magnetic resonance imaging (MRI) has been widely utilized for analysis and diagnosis of brain diseases. Automatic segmentation of brain tumors is a challenging task for computer-aided diagnosis due to low-tissue contrast in the…

Image and Video Processing · Electrical Eng. & Systems 2020-11-22 Mohammad Hamghalam , Baiying Lei , Tianfu Wang

Glioblastoma is the most malignant type of central nervous system tumor with GBM subtypes cleaved based on molecular level gene alterations. These alterations are also happened to affect the histology. Thus, it can cause visible changes in…

Quantitative Methods · Quantitative Biology 2020-10-28 Navodini Wijethilake , Mobarakol Islam , Dulani Meedeniya , Charith Chitraranjan , Indika Perera , Hongliang Ren

We apply deep learning (DL) on Magnetic resonance spectroscopy (MRS) data for the task of brain tumor detection. Medical applications often suffer from data scarcity and corruption by noise. Both of these problems are prominent in our data…

Machine Learning · Computer Science 2021-12-17 Diyuan Lu , Gerhard Kurz , Nenad Polomac , Iskra Gacheva , Elke Hattingen , Jochen Triesch

Brain tumor is a life-threatening problem and hampers the normal functioning of the human body. The average five-year relative survival rate for malignant brain tumors is 35.6 percent. For proper diagnosis and efficient treatment planning,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Vidhyapriya Ranganathan , Celshiya Udaiyar , Jaisree Jayanth , Meghaa P , Srija B , Uthra S

In this paper we present a method for estimating unknown parameters that appear on an avascular, spheric tumour growth model. The model for the tumour is based on nutrient driven growth of a continuum of live cells, whose birth and death…

Mathematical Physics · Physics 2012-09-14 D. A. Knopoff , D. R. Fernández , G. A. Torres , C. V. Turner

The use of mathematical models to make predictions about tumor growth and response to treatment has become increasingly more prevalent in the clinical setting. The level of complexity within these models ranges broadly, and the calibration…

Quantitative Methods · Quantitative Biology 2021-12-28 Allison L. Lewis , Kathleen M. Storey , Heyrim Cho , Anna C. Zittle

Intracranial tumors are groups of cells that usually grow uncontrollably. One out of four cancer deaths is due to brain tumors. Early detection and evaluation of brain tumors is an essential preventive medical step that is performed by…

Image and Video Processing · Electrical Eng. & Systems 2020-02-07 Zahra Sobhaninia , Safiyeh Rezaei , Nader Karimi , Ali Emami , Shadrokh Samavi

Gliomas are the most common primary tumors of the central nervous system. Multimodal MRI is widely used for the preliminary screening of gliomas and plays a crucial role in auxiliary diagnosis, therapeutic efficacy, and prognostic…

Image and Video Processing · Electrical Eng. & Systems 2025-05-27 Yihao Liu , Zhihao Cui , Liming Li , Junjie You , Xinle Feng , Jianxin Wang , Xiangyu Wang , Qing Liu , Minghua Wu