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Accurate segmentation of brain tumors is vital for diagnosis, surgical planning, and treatment monitoring. Deep learning has advanced on benchmarks, but two issues limit clinical use: no uncertainty estimates for errors and no segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Andrew Zhou

Existing approaches to modeling the dynamics of brain tumor growth, specifically glioma, employ biologically inspired models of cell diffusion, using image data to estimate the associated parameters. In this work, we propose an alternative…

In advancing discrete-based computational cancer models towards clinical applications, one faces the dilemma of how to deal with an ever growing amount of biomedical data that ought to be incorporated eventually in one form or another.…

Cell Behavior · Quantitative Biology 2008-06-26 Le Zhang , L. Leon Chen , Thomas S. Deisboeck

This study presents a convolutional neural network (CNN)-based approach for the multi-class classification of brain tumors using magnetic resonance imaging (MRI) scans. We utilize a publicly available dataset containing MRI images…

Image and Video Processing · Electrical Eng. & Systems 2025-05-07 Natnael Alemayehu

Patient-derived cells (PDC) mouse xenografts are increasingly important tools in glioblastoma (GBM) research, essential to investigate case-specific growth patterns and treatment responses. Despite the central role of xenograft models in…

Quantitative Methods · Quantitative Biology 2024-03-15 Adam A. Malik , Cecilia Krona , Soumi Kundu , Philip Gerlee , Sven Nelander

Glioblastoma exhibits diverse, infiltrative, and patient-specific growth patterns that are only partially visible on routine MRI, making it difficult to reliably assess true tumor extent and personalize treatment planning and follow-up. We…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Valentin Biller , Niklas Bubeck , Lucas Zimmer , Ayhan Can Erdur , Sandeep Nagar , Anke Meyer-Baese , Daniel Rückert , Benedikt Wiestler , Jonas Weidner

Deep learning has emerged as a prominent field in recent literature, showcasing the introduction of models that utilize transfer learning to achieve remarkable accuracies in the classification of brain tumor MRI images. However, the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-15 Raza Imam , Mohammed Talha Alam

This research presents an enhanced approach for precise segmentation of brain tumor masses in magnetic resonance imaging (MRI) using an advanced 3D-UNet model combined with a Context Transformer (CoT). By architectural expansion CoT, the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Thien-Qua T. Nguyen , Hieu-Nghia Nguyen , Thanh-Hieu Bui , Thien B. Nguyen-Tat , Vuong M. Ngo

Glioma, the prevalent primary brain tumor, exhibits diverse aggressiveness levels and prognoses. Precise classification of glioma is paramount for treatment planning and predicting prognosis. This study aims to develop an algorithm to fuse…

Image and Video Processing · Electrical Eng. & Systems 2026-03-10 Kiranmayee Janardhan , Christy Bobby Thomas

Brain tumor analysis in Magnetic Resonance Imaging (MRI) is crucial for accurate diagnosis and treatment planning. However, the task remains challenging due to the complexity and variability of tumor appearances, as well as the scarcity of…

Image and Video Processing · Electrical Eng. & Systems 2024-07-18 Yiqing Shen , Guannan He , Mathias Unberath

Accurately predicting early recurrence in brain tumor patients following surgical resection remains a clinical challenge. This study proposes a multi-modal machine learning framework that integrates structural MRI features with clinical…

Machine Learning · Computer Science 2025-09-03 Cheng Cheng , Zeping Chen , Rui Xie , Peiyao Zheng , Xavier Wang

Accurate prognosis for Glioblastoma (GBM) using deep learning (DL) is hindered by extreme spatial and structural heterogeneity. Moreover, inconsistent MRI acquisition protocols across institutions hinder generalizability of models.…

Machine Learning · Computer Science 2026-02-13 Ankita Paul , Wenyi Wang

Accurate brain tumor classification is crucial in medical imaging to ensure reliable diagnosis and effective treatment planning. This study introduces a novel double ensembling framework that synergistically combines pre-trained deep…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Zahid Ullah , Jihie Kim

DNA microarray technology enables the simultaneous measurement of expression levels of thousands of genes, thereby facilitating the understanding of the molecular mechanisms underlying complex diseases such as brain tumors and the…

Machine Learning · Computer Science 2025-08-29 Emine Akpinar , Batuhan Hangun , Murat Oduncuoglu , Oguz Altun , Onder Eyecioglu , Zeynel Yalcin

Gliomas are the most common primary brain tumors, evolving from the cerebral supportive cells. For clinical follow-up, the evaluation of the preoperative tumor volume is essential. Volumetric assessment of tumor volume with manual…

Computational Engineering, Finance, and Science · Computer Science 2011-03-10 Jan Egger , Miriam H. A. Bauer , Daniela Kuhnt , Christoph Kappus , Barbara Carl , Bernd Freisleben , Christopher Nimsky

Gliomas, a common type of malignant brain tumor, present significant surgical challenges due to their similarity to healthy tissue. Preoperative Magnetic Resonance Imaging (MRI) images are often ineffective during surgery due to factors…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Samir Kassam , Angelo Markham , Katie Vo , Yashas Revanakara , Michael Lam , Kevin Zhu

Accurately identifying cancer samples is crucial for precise diagnosis and effective patient treatment. Traditional methods falter with high-dimensional and high feature-to-sample count ratios, which are critical for classifying cancer…

Machine Learning · Computer Science 2025-01-14 Tareque Mohmud Chowdhury , Farzana Tabassum , Sabrina Islam , Abu Raihan Mostofa Kamal

Glioblastoma is profoundly heterogeneous in regional microstructure and vasculature. Characterizing the spatial heterogeneity of glioblastoma could lead to more precise treatment. With unsupervised learning techniques, glioblastoma…

Machine Learning · Computer Science 2021-08-24 Yifan Li , Chao Li , Yiran Wei , Stephen Price , Carola-Bibiane Schönlieb , Xi Chen

This study explores the application of Quantum Convolutional Neural Networks (QCNNs) for brain tumor classification using MRI images, leveraging quantum computing for enhanced computational efficiency. A dataset of 3,264 MRI images,…

The integration of machine learning in magnetic resonance imaging (MRI), specifically in neuroimaging, is proving to be incredibly effective, leading to better diagnostic accuracy, accelerated image analysis, and data-driven insights, which…

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