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Semi-linear elliptic Partial Differential Equations (PDEs) such as the non-linear Poisson Boltzmann Equation (nPBE) is highly relevant for non-linear electrostatics in computational biology and chemistry. It is of particular importance for…

Numerical Analysis · Mathematics 2023-09-29 Brian Choi , Jie Xu , Trevor Norton , Mark Kon , Julio Enrique Castrillon-Candas

The Poisson-Boltzmann equation (PBE) is an implicit solvent continuum model for calculating the electrostatic potential and energies of ionic solvated biomolecules. However, its numerical solution remains a significant challenge due strong…

Numerical Analysis · Mathematics 2023-06-13 Cleophas Kweyu , Venera Khoromskaia , Boris Khoromskij , Matthias Stein , Peter Benner

The nonlinear Poisson-Boltzmann equation (NPBE) is an elliptic partial differential equation used in applications such as protein interactions and biophysical chemistry (among many others). It describes the nonlinear electrostatic potential…

Numerical Analysis · Mathematics 2023-09-29 Trevor Norton , Jie Xu , Brian Choi , Mark Kon , Julio Enrique Castrillón-Candás

We consider a class of nonlinear elliptic problems associated with models in biophysics, which are described by the Poisson-Boltzmann equation (PBE). We prove mathematical correctness of the problem, study a suitable class of…

Numerical Analysis · Mathematics 2020-12-15 Johannes Kraus , Svetoslav Nakov , Sergey Repin

The Poisson-Boltzmann equation (PBE) is a fundamental implicit solvent continuum model for calculating the electrostatic potential of large ionic solvated biomolecules. However, its numerical solution encounters severe challenges arising…

Numerical Analysis · Mathematics 2021-03-02 Cleophas Kweyu , Lihong Feng , Matthias Stein , Peter Benner

We consider the nonlinear Poisson-Boltzmann equation in the context of electrostatic models for a biological macromolecule, embedded in a bounded domain containing a solution of an arbitrary number of ionic species which is not necessarily…

Analysis of PDEs · Mathematics 2022-04-26 José A. Iglesias , Svetoslav Nakov

The Poisson-Boltzmann equation (PBE) models the electrostatic interactions of charged bodies such as molecules and proteins in an electrolyte solvent. The PBE is a challenging equation to solve numerically due to the presence of…

Numerical Analysis · Mathematics 2018-07-17 Jehanzeb H. Chaudhry

A widely used electrostatics model in the biomolecular modeling community, the nonlinear Poisson-Boltzmann equation, along with its finite element approximation, are analyzed in this paper. A regularized Poisson-Boltzmann equation is…

Numerical Analysis · Mathematics 2010-01-12 Long Chen , Michael Holst , Jinchao Xu

The Landau--Lifshitz--Bloch equation (LLBE) describes the evolution of the magnetic spin field in ferromagnets at high temperatures. In this paper, we study the numerical approximation of the LLBE on bounded polytopal domains in…

Numerical Analysis · Mathematics 2026-02-17 Kim-Ngan Le , Agus L. Soenjaya , Thanh Tran

A new protocol for linearization of the Poisson-Boltzmann equation is proposed and the resultant electrostatic equation coincides formally with the Debye-Huckel equation, the solution of which is well known for many electrostatic problems.…

Chemical Physics · Physics 2014-10-28 R. Tsekov

We establish existence, uniqueness and optimal regularity results for very weak solutions to certain nonlinear elliptic boundary value problems. We introduce structural asymptotic assumptions of Uhlenbeck type on the nonlinearity, which are…

Analysis of PDEs · Mathematics 2016-08-03 Miroslav Bulíček , Lars Diening , Sebastian Schwarzacher

We prove the existence and uniqueness of weak solution of a Neumann boundary problem for an elliptic partial differential equation (PDE for short) with a singular divergence term which can only be understood in a weak sense. A probabilistic…

Probability · Mathematics 2018-04-24 Xue Yang , Jing Zhang

We prove an existence and uniqueness result for Neumann boundary problem of a parabolic partial differential equation (PDE for short) with a singular nonlinear divergence term which can only be understood in a weak sense. A probabilistic…

Probability · Mathematics 2018-02-22 Xue Yang , Jing Zhang

In this work, we present a result on the local existence and uniqueness of solutions to nonlinear Partial Differential-Algebraic Equations (PDAEs). By applying established theoretical results, we identify the conditions that guarantee the…

Analysis of PDEs · Mathematics 2025-02-11 Seyyid Ali Benabdallah

We establish the existence theory of several commonly used finite element (FE) nonlinear fully discrete solutions, and the convergence theory of a linearized iteration. First, it is shown for standard FE, SUPG and edge-averaged method…

Numerical Analysis · Mathematics 2023-12-04 Yang Liu , Shi Shu , Ying Yang

The non-linear Poisson-Boltzmann equation for a circular, uniformly charged platelet, confined together with co- and counter-ions to a cylindrical cell, is solved semi-analytically by transforming it into an integral equation and solving…

Soft Condensed Matter · Physics 2009-10-31 R. J. F. Leote de Carvalho , E. Trizac , J. P Hansen

We develop an efficient and reliable adaptive finite element method (AFEM) for the nonlinear Poisson-Boltzmann equation (PBE). We first examine the regularization technique of Chen, Holst, and Xu; this technique made possible the first a…

Numerical Analysis · Mathematics 2010-10-01 Michael Holst , James Andrew McCammon , Zeyun Yu , Yongcheng Zhou , Yunrong Zhu

We prove existence of global weak solutions for the Nernst-Planck-Poisson problem which describes the evolution of concentrations of charged species $X_1, ..., X_P$ subject to Fickian diffusion and chemical reactions in the presence of an…

Analysis of PDEs · Mathematics 2016-04-01 Dieter Bothe , André Fischer , Michel Pierre , Guillaume Rolland

We consider the problem of existence and uniqueness of strong a.e. solutions $u: \mathbb{R}^n \longrightarrow \mathbb{R}^N$ to the fully nonlinear PDE system \[\label{1} \tag{1} F(\cdot,D^2u ) \,=\, f, \ \ \text{ a.e. on }\mathbb{R}^n, \]…

Analysis of PDEs · Mathematics 2016-03-01 Nikos Katzourakis

The existence and multiplicity of solutions to a quasilinear, elliptic partial differential equation (PDE) with singular non-linearity is analyzed. The PDE is a recently derived variant of a canonical model used in the modeling of…

Analysis of PDEs · Mathematics 2011-11-02 Nicholas D. Brubaker , Alan E. Lindsay
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