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The paper highlights the role of a positive feedback gating mechanism at the cellular level in the robust- ness and modulation properties of rhythmic activities at the circuit level. The results are presented in the context of half-center…

Neurons and Cognition · Quantitative Biology 2014-12-22 Julie Dethier , Guillaume Drion , Alessio Franci , Rodolphe Sepulchre

Deep feedforward and recurrent rate-based neural networks have become successful functional models of the brain, but they neglect obvious biological details such as spikes and Dale's law. Here we argue that these details are crucial in…

Neurons and Cognition · Quantitative Biology 2023-12-29 William F. Podlaski , Christian K. Machens

We consider two neuronal networks coupled by long-range excitatory interactions. Oscillations in the gamma frequency band are generated within each network by local inhibition. When long-range excitation is weak, these oscillations…

Neurons and Cognition · Quantitative Biology 2009-11-13 Demian Battaglia , Nicolas Brunel , David Hansel

Positive feedback regulation is ubiquitous in cell signaling networks, often leading to binary outcomes in response to graded stimuli. However, the role of such feedbacks in clustering, and in spatial spreading of activated molecules, has…

Soft Condensed Matter · Physics 2015-05-13 Jayajit Das , Mehran Kardar , Arup K. Chakraborty

Periodic neural activity not locked to the stimulus or to motor responses is usually ignored. Here, we present new tools for modeling and quantifying the information transmission based on periodic neural activity that occurs with…

Neurons and Cognition · Quantitative Biology 2008-12-05 Kilian Koepsell , Friedrich T. Sommer

We study a problem of designing ``robust'' external excitations for control and synchronization of an assembly of homotypic harmonic oscillators representing so-called theta neurons. The model of theta neurons (Theta model) captures, in…

Optimization and Control · Mathematics 2024-09-23 Roman Chertovskih , Nikolay Pogodaev , Maxim Staritsyn , Joaquim Da Silva Sewane , Antonio Pedro Aguiar

Central to the functioning of a living cell is its ability to control the readout or expression of information encoded in the genome. In many cases, a single transcription factor protein activates or represses the expression of many genes.…

Molecular Networks · Quantitative Biology 2013-05-29 Aleksandra M. Walczak , Gapser Tkacik , William Bialek

The edge-of-chaos dynamics of wide randomly initialized low-rank feedforward networks are analyzed. Formulae for the optimal weight and bias variances are extended from the full-rank to low-rank setting and are shown to follow from…

Machine Learning · Statistics 2023-02-01 Thiziri Nait Saada , Jared Tanner

In computer simulations of spiking neural networks, often it is assumed that every two neurons of the network are connected by a probability of 2\%, 20\% of neurons are inhibitory and 80\% are excitatory. These common values are based on…

Neurons and Cognition · Quantitative Biology 2015-03-06 Hamed Seyed-allaei

Cross-correlations in the activity in neural networks are commonly used to characterize their dynamical states and their anatomical and functional organizations. Yet, how these latter network features affect the spatiotemporal structure of…

Neurons and Cognition · Quantitative Biology 2018-09-26 Ran Darshan , Carl van Vreeswijk , David Hansel

We study the statistical properties of a simple genetic regulatory network that provides heterogeneity within a population of cells. This network consists of a binary genetic switch in which stochastic flipping between the two switch states…

Soft Condensed Matter · Physics 2009-03-31 Paolo Visco , Rosalind J. Allen , Martin R. Evans

Synapses change on multiple timescales, ranging from milliseconds to minutes, due to a combination of both short- and long-term plasticity. Here we develop an extension of the common Generalized Linear Model to infer both short- and…

Neurons and Cognition · Quantitative Biology 2022-08-15 Ganchao Wei , Ian H. Stevenson

Deep cognitive attention is characterized by heightened gamma oscillations and coordinated visual behavior. Despite the physiological importance of these mechanisms, computational studies rarely synthesize these modalities or identify the…

Neurons and Cognition · Quantitative Biology 2026-01-13 Sobhana Jahan , Saydul Akbar Murad , Nick Rahimi , Noorbakhsh Amiri Golilarz

Spiking neural networks coupled with neuromorphic hardware and event-based sensors are getting increased interest for low-latency and low-power inference at the edge. However, multiple spiking neuron models have been proposed in the…

Neural and Evolutionary Computing · Computer Science 2022-11-16 Mohamed Sadek Bouanane , Dalila Cherifi , Elisabetta Chicca , Lyes Khacef

This work is part of an effort to understand the neural basis for our visual system's ability, or failure, to accurately track moving visual signals. We consider here a ring model of spiking neurons, intended as a simplified computational…

Neurons and Cognition · Quantitative Biology 2016-01-13 Guillaume Lajoie , Lai-Sang Young

The brain may be thought of as a many-body architecture with a spatio-temporal dynamics described by neuronal structures. The oscillatory nature of brain activity allows these structures (nodes) to be described as a set of coupled…

Neurons and Cognition · Quantitative Biology 2021-02-03 J. Mendoza-Ruiz , C. E. Alonso-Malaver , M. Valderrama , O. A. Rosso , J. H. Martínez

This paper presents a vehicle lateral controller based on spiking neural networks capable of replicating the behavior of a model-based controller but with the additional ability to perform online adaptation. By making use of neural…

Systems and Control · Electrical Eng. & Systems 2022-07-06 Javier Pérez , Manuel A. Vargas , Juan A. Cabrera , Juan J. Castillo , Barys Shyrokau

The mammalian hippocampus plays a principal role in producing a cognitive map of space---an internalized representation of the animal's environment. The neuronal mechanisms producing this map depend primarily on the temporal structure of…

Neurons and Cognition · Quantitative Biology 2016-03-22 Edward Basso , Mamiko Arai , Yuri Dabaghian

Recurrent neural nets are widely used for predicting temporal data. Their inherent deep feedforward structure allows learning complex sequential patterns. It is believed that top-down feedback might be an important missing ingredient which…

Machine Learning · Computer Science 2016-10-20 Kamil M Rocki

Winner Take All (WTA) circuits a type of Spiking Neural Networks (SNN) have been suggested as facilitating the brain's ability to process information in a Bayesian manner. Research has shown that WTA circuits are capable of approximating…

Artificial Intelligence · Computer Science 2023-08-30 Otto van der Himst , Leila Bagheriye , Johan Kwisthout