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Diagnostic test accuracy studies typically report the number of true positives, false positives, true negatives and false negatives. There usually exists a negative association between the number of true positives and true negatives,…

Methodology · Statistics 2015-11-06 Aristidis K. Nikoloulopoulos

Continuous-time event data are common in applications such as individual behavior data, financial transactions, and medical health records. Modeling such data can be very challenging, in particular for applications with many different types…

Machine Learning · Statistics 2020-11-09 Alex Boyd , Robert Bamler , Stephan Mandt , Padhraic Smyth

We describe and analyze some Monte Carlo methods for manifolds in Euclidean space defined by equality and inequality constraints. First, we give an MCMC sampler for probability distributions defined by un-normalized densities on such…

Numerical Analysis · Mathematics 2017-09-21 Emilio Zappa , Miranda Holmes-Cerfon , Jonathan Goodman

In this paper, we propose an efficient importance sampling algorithm for rare event simulation under copula models. In the algorithm, the derived optimal probability measure is based on the criterion of minimizing the variance of the…

Computation · Statistics 2025-04-07 Siang Cheng , Cheng-Der Fuh , Tianxiao Pang

Monte Carlo event generators are the central interface between theoretical calculations and experimental measurements in collider physics. Over several decades, a comprehensive and highly modular ecosystem of tools has developed around…

High Energy Physics - Phenomenology · Physics 2026-05-18 Melissa van Beekveld , Enrico Bothmann , Andy Buckley , Christian Gütschow , Peter Skands , Ramon Winterhalder

Nowadays, the confidentiality of data and information is of great importance for many companies and organizations. For this reason, they may prefer not to release exact data, but instead to grant researchers access to approximate data. For…

Methodology · Statistics 2021-12-24 Zahra A. Shirazi , João Pedro A. R. da Silva , Camila P. E. de Souza

The increasing occurrence of continuous anomalous weather events has intensified the uncertainty in wind and photovoltaic power generation, posing significant challenges to the operation and optimization of building integrated energy…

Optimization and Control · Mathematics 2025-04-16 Deyi Shao , Hongru Li , Jingsheng Li , Xia Yu , Xiaoyu Sun , Bowen Han

Understanding causality in event sequences where outcome labels such as diseases or system failures arise from preceding events like symptoms or error codes is critical. Yet remains an unsolved challenge across domains like healthcare or…

Machine Learning · Computer Science 2025-12-15 Hugo Math , Rainer Lienhart

Modeling of high-dimensional data is very important to categorize different classes. We develop a new mixture model called Multinomial cluster-weighted model (MCWM). We derive the identifiability of a general class of MCWM. We estimate the…

Methodology · Statistics 2022-08-25 Kehinde Olobatuyi , Oludare Ariyo

We have developed a neural network model to perform event reconstruction of Compton telescopes. This model reconstructs events that consist of three or more interactions in a detector. It is essential for Compton telescopes to determine the…

Instrumentation and Methods for Astrophysics · Physics 2022-06-22 Satoshi Takashima , Hirokazu Odaka , Hiroki Yoneda , Yuto Ichinohe , Aya Bamba , Tsuguo Aramaki , Yoshiyuki Inoue

Traditional survival analysis methods often struggle with complex time-dependent data,failing to capture and interpret dynamic characteristics adequately.This study aims to evaluate the performance of three long-sequence…

Machine Learning · Computer Science 2024-07-22 Runquan Zhang , Jiawen Jiang , Xiaoping Shi

We develop a novel multi-factor copula model for multivariate spatial extremes, which is designed to capture the different combinations of marginal and cross-extremal dependence structures within and across different spatial random fields.…

Methodology · Statistics 2022-06-24 Yan Gong , Raphaël Huser

A multivariate quantile regression model with a factor structure is proposed to study data with many responses of interest. The factor structure is allowed to vary with the quantile levels, which makes our framework more flexible than the…

Methodology · Statistics 2020-01-22 Shih-Kang Chao , Wolfgang Karl Härdle , Ming Yuan

Applications that require substantial computational resources today cannot avoid the use of heavily parallel machines. Embracing the opportunities of parallel computing and especially the possibilities provided by a new generation of…

Computational Physics · Physics 2017-09-14 Martin Weigel

Numerical models are increasingly used for non-invasive diagnosis and treatment planning in coronary artery disease, where service-based technologies have proven successful in identifying hemodynamically significant and hence potentially…

Medical Physics · Physics 2020-05-01 Jongmin Seo , Casey Fleeter , Andrew M. Kahn , Alison L. Marsden , Daniele E. Schiavazzi

Kernel-based multi-marker tests for survival outcomes use primarily the Cox model to adjust for covariates. The proportional hazards assumption made by the Cox model could be unrealistic, especially in the long-term follow-up. We develop a…

Methodology · Statistics 2024-01-19 Chenxi Li , Di Wu , Qing Lu

Multiple indications of disease progression found in a cancer patient by loco-regional relapse, distant metastasis and death. Early identification of these indications is necessary to change the treatment strategy. Biomarkers play an…

Applications · Statistics 2021-07-23 Atanu Bhattacharjee , Gajendra K. Vishwakarma , Souvik Banerjee

In longitudinal data a response variable is measured over time, or under different conditions, for a cohort of individuals. In many situations all intended measurements are not available which results in missing values. If the missing value…

Methodology · Statistics 2022-08-10 Ahmed M. Gad , Nesma M. Darwish

Recurrent events are common and important clinical trial endpoints in many disease areas, e.g., cardiovascular hospitalizations in heart failure, relapses in multiple sclerosis, or exacerbations in asthma. During a trial, patients may…

Methodology · Statistics 2026-04-08 Jiren Sun , Tobias Mutze , Richard Cook , Tianmeng Lyu

Background and objective: Uncertainty quantification is a pivotal field that contributes to realizing reliable and robust systems. It becomes instrumental in fortifying safe decisions by providing complementary information, particularly…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Jamil Fayyad , Shadi Alijani , Homayoun Najjaran