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Heterogeneity is a dominant factor in the behaviour of many biological processes. Despite this, it is common for mathematical and statistical analyses to ignore biological heterogeneity as a source of variability in experimental data.…

Learning from multiple sources of information is an important problem in machine-learning research. The key challenges are learning representations and formulating inference methods that take into account the complementarity and redundancy…

Machine Learning · Statistics 2018-11-20 Richard Kurle , Stephan Günnemann , Patrick van der Smagt

We investigate the relationship between system identification and intervention design in dynamical systems. While previous research demonstrated how identifiable representation learning methods, such as Independent Component Analysis (ICA),…

Machine Learning · Computer Science 2024-02-19 Goutham Rajendran , Patrik Reizinger , Wieland Brendel , Pradeep Ravikumar

In unsupervised causal representation learning for sequential data with time-delayed latent causal influences, strong identifiability results for the disentanglement of causally-related latent variables have been established in stationary…

Machine Learning · Computer Science 2024-08-02 Xiangchen Song , Weiran Yao , Yewen Fan , Xinshuai Dong , Guangyi Chen , Juan Carlos Niebles , Eric Xing , Kun Zhang

While hidden class models of various types arise in many statistical applications, it is often difficult to establish the identifiability of their parameters. Focusing on models in which there is some structure of independence of some of…

Statistics Theory · Mathematics 2009-09-01 Elizabeth S. Allman , Catherine Matias , John A. Rhodes

Missing data is a ubiquitous challenge in data analysis, often leading to biased and inaccurate results. Traditional imputation methods usually assume that the missingness mechanism is missing-at-random (MAR), where the missingness is…

Methodology · Statistics 2026-03-30 Huiming Xie , Fei Xue , Xiao Wang

In designing generative models, it is commonly believed that in order to learn useful latent structure, we face a fundamental tension between expressivity and structure. In this paper we challenge this view by proposing a new approach to…

Machine Learning · Statistics 2026-04-03 Alex Markham , Isaac Hirsch , Jeri A. Chang , Liam Solus , Bryon Aragam

Independent component analysis (ICA) is a widely used BSS method that can uniquely achieve source recovery, subject to only scaling and permutation ambiguities, through the assumption of statistical independence on the part of the latent…

Machine Learning · Statistics 2018-01-29 Zois Boukouvalas

Learning representations that capture the underlying data generating process is a key problem for data efficient and robust use of neural networks. One key property for robustness which the learned representation should capture and which…

Machine Learning · Computer Science 2022-06-24 Mathieu Chevalley , Charlotte Bunne , Andreas Krause , Stefan Bauer

This paper explores unsupervised learning of parsing models along two directions. First, which models are identifiable from infinite data? We use a general technique for numerically checking identifiability based on the rank of a Jacobian…

Machine Learning · Statistics 2012-06-15 Daniel Hsu , Sham M. Kakade , Percy Liang

We study a marginal empirical likelihood approach in scenarios when the number of variables grows exponentially with the sample size. The marginal empirical likelihood ratios as functions of the parameters of interest are systematically…

Statistics Theory · Mathematics 2013-11-07 Jinyuan Chang , Cheng Yong Tang , Yichao Wu

Observational studies provide invaluable opportunities to draw causal inference, but they may suffer from biases due to pretreatment difference between treated and control units. Matching is a popular approach to reduce observed covariate…

Methodology · Statistics 2025-09-17 Xinran Li

The inference of causal relationships using observational data from partially observed multivariate systems with hidden variables is a fundamental question in many scientific domains. Methods extracting causal information from conditional…

Machine Learning · Statistics 2020-10-13 Daniel Chicharro , Michel Besserve , Stefano Panzeri

Temporally evolving systems are typically modeled by dynamic equations. A key challenge in accurate modeling is understanding the causal relationships between subsystems, as well as identifying the presence and influence of unobserved…

Methodology · Statistics 2024-10-28 András Telcs , Marcell T. Kurbucz , Antal Jakovác

Conditional-independence-based discovery uses statistical tests to identify a graphical model that represents the independence structure of variables in a dataset. These tests, however, can be unreliable, and algorithms are sensitive to…

Machine Learning · Computer Science 2026-04-21 Philipp M. Faller , Dominik Janzing

The modeling and prediction of multivariate spatio-temporal data involve numerous challenges. Dimension reduction methods can significantly simplify this process, provided that they account for the complex dependencies between variables and…

Machine Learning · Statistics 2025-12-18 Mika Sipilä , Klaus Nordhausen , Sara Taskinen

Independent Component Analysis (ICA) is a technique for unsupervised exploration of multi-channel data that is widely used in observational sciences. In its classic form, ICA relies on modeling the data as linear mixtures of non-Gaussian…

Machine Learning · Statistics 2018-08-01 Pierre Ablin , Jean-François Cardoso , Alexandre Gramfort

We introduce a new machine-learning-based approach, which we call the Independent Classifier networks (InClass nets) technique, for the nonparameteric estimation of conditional independence mixture models (CIMMs). We approach the estimation…

Machine Learning · Statistics 2020-09-02 Konstantin T. Matchev , Prasanth Shyamsundar

Independent Component Analysis (ICA) was introduced in the 1980's as a model for Blind Source Separation (BSS), which refers to the process of recovering the sources underlying a mixture of signals, with little knowledge about the source…

Statistics Theory · Mathematics 2026-02-09 Syamantak Kumar , Purnamrita Sarkar , Peter Bickel , Derek Bean

Estimating causal effects from observational data requires identifying valid adjustment sets. This task is especially challenging in realistic settings where latent confounding and feedback loops are present. Existing approaches typically…

Machine Learning · Computer Science 2026-05-08 Ana Leticia Garcez Vicente , Gijs van Seeventer , Saber Salehkaleybar