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Understanding biological phenomena requires a systemic approach that incorporates different mechanisms acting on different spatial and temporal scales, since in organisms the workings of all components, such as organelles, cells, and organs…

Tissues and Organs · Quantitative Biology 2015-09-14 Yuri K. Shestopaloff , Ivo F. Sbalzarini

This paper investigates the role of size in biological organisms. More specifically, how the energy demand, expressed by the metabolic rate, changes according to the mass of an organism. Empirical evidence suggests a power-law relation…

Other Quantitative Biology · Quantitative Biology 2021-05-05 Fabiano L. Ribeiro , William R. L. S. Pereira

Cell migration is closely linked to cell shape, yet cell size is often assumed to remain constant. This assumption is challenged by recent experiments showing that cells undergo volume loss during spreading and swelling upon activation,…

Biological Physics · Physics 2025-05-28 Jonathan E. Ron , Ram M. Adar

Cellular cortex, which is a highly viscous thin cytoplasmic layer just below the cell membrane, controls the cell's mechanical properties, which can be characterized by a hydrodynamic length scale $\ell$. Cells actively regulate $\ell$ via…

Biological Physics · Physics 2018-06-08 Saroj Kumar Nandi

This paper focuses on studying a model for molecular motors responsible for the bending of the axoneme in the flagella of microorganisms. The model is a coupled system of partial differential equations inspired by J\"ulicher et al. or…

Numerical Analysis · Mathematics 2025-04-17 François Alouges , Irene Anello , Antonio DeSimone , Aline Lefebvre-Lepot , Jessie Levillain

The structure of very complicated irregular "microscopic" (local) entropy fluctuations around a big separated "macroscopic" (global) fluctuation in the statistical equilibrium was studied in numerical experiments on a simple 2--freedom…

Chaotic Dynamics · Physics 2007-05-23 Boris Chirikov , Oleg Zhirov

Using a population dynamics inspired by an ensemble of growing cells, a set of fluctuation theorems linking observables measured at the lineage and population levels are derived. One of these relations implies specific inequalities…

Populations and Evolution · Quantitative Biology 2021-11-08 Reinaldo García-García , Arthur Genthon , David Lacoste

We focus on various measures of the fluctuations of the sequence of intervals between beats of the human heart, and how such fluctuations can be used to assess the presence or likelihood of cardiovascular disease. We examine sixteen such…

Biological Physics · Physics 2016-09-08 Malvin C. Teich , Steven B. Lowen , Bradley M. Jost , Karin Vibe-Rheymer , Conor Heneghan

Euler buckling is the elastic instability of a column subjected to longitudinal compression forces at its ends. The buckling instability occurs when the compressing load reaches a critical value and an infinitesimal fluctuation leads to a…

Soft Condensed Matter · Physics 2021-05-26 Marc Suñé , John S. Wettlaufer

Open cellular solids usually possess random microstructures that may contain a characteristic length scale, such as the cell size. This gives rise to size dependent mechanical properties where large systems behave differently from small…

Materials Science · Physics 2018-01-03 Stefan Liebenstein , Stefan Sandfeld , Michael Zaiser

To swim through a viscous fluid, a flagellated bacterium must overcome the fluid drag on its body by rotating a flagellum or a bundle of multiple flagella. Because the drag increases with the size of bacteria, it is expected theoretically…

This chapter deals with error and uncertainty in data. Treats their measuring methods and meaning. It shows that uncertainty is a natural property of many data sets. Uncertainty is fundamental for the survival os living species, Uncertainty…

Other Statistics · Statistics 2024-10-10 Carlos Sevcik

A fundamental question in biology is to understand how patterns and shapes emerge from the collective interplay of large numbers of cells. Cells forming two-dimensional epithelial tissues behave as active materials that undergo remodeling…

The elastic properties of two-component bilayer membranes are studied using a coarse grain model for amphiphilic molecules. The two species of amphiphiles considered here differ only in their length. Molecular Dynamics simulations are…

Soft Condensed Matter · Physics 2007-05-23 Alberto Imparato , Julian C. Shillcock , Reinhard Lipowsky

The fast blood stream of animals is associated with large shear stresses. Consequently, blood cells have evolved a special morphology and a specific internal architecture allowing them to maintain their integrity over several weeks. For…

Subcellular Processes · Quantitative Biology 2022-10-12 Serge Dmitrieff , Adolfo Alsina , Aastha Mathur , François Nédélec

In hydrodynamic descriptions of lipid bilayers, the membrane is often approximated as being impermeable to the surrounding, solute-containing fluid. However, biological and in vitro lipid membranes are influenced by their permeability and…

Soft Condensed Matter · Physics 2026-02-24 Amaresh Sahu

Fluctuations and noise may alter the behavior of dynamical systems considerably. For example, oscillations may be sustained by demographic fluctuations in biological systems where a stable fixed point is found in the absence of noise. We…

Adaptation and Self-Organizing Systems · Physics 2009-11-13 Richard P. Boland , Tobias Galla , Alan J. McKane

We present a brief introduction to the statistical properties of systems with large fluctuations. We point out that for such systems the relevant statistical quantities are scaling exponents and the nature of fluctuations is completely…

Astrophysics · Physics 2007-05-23 Francesco Sylos Labini , Andrea Gabrielli

We propose a new method to analyze fluctuations in the strength function phenomena in highly excited nuclei. Extending the method of multifractal analysis to the cases where the strength fluctuations do not obey power scaling laws, we…

Nuclear Theory · Physics 2009-10-31 Hirokazu Aiba , Masayuki Matsuo

We study numerically a Ginzburg-Landau type equation for micelles in two dimensions. The domain size and the interface length of a cellular structure are controlled by two feedback terms. The deformation and the successive splitting of the…

Soft Condensed Matter · Physics 2009-07-01 Hidetsugu Sakaguchi