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SDE-based methods such as denoising diffusion probabilistic models (DDPMs) have shown remarkable success in real-world sample generation tasks. Prior analyses of DDPMs have been focused on the exponential Euler discretization, showing…

Machine Learning · Computer Science 2025-11-10 Matthew S. Zhang , Stephen Huan , Jerry Huang , Nicholas M. Boffi , Sitan Chen , Sinho Chewi

In deep learning, dense layer connectivity has become a key design principle in deep neural networks (DNNs), enabling efficient information flow and strong performance across a range of applications. In this work, we model densely connected…

Machine Learning · Computer Science 2025-10-03 Jinshu Huang , Haibin Su , Xue-Cheng Tai , Chunlin Wu

Deep neural networks (DNN) have been used successfully in many scientific problems for their high prediction accuracy, but their application to genetic studies remains challenging due to their poor interpretability. In this paper, we…

Machine Learning · Computer Science 2021-10-01 Peyman H. Kassani , Fred Lu , Yann Le Guen , Zihuai He

We propose lookahead diffusion probabilistic models (LA-DPMs) to exploit the correlation in the outputs of the deep neural networks (DNNs) over subsequent timesteps in diffusion probabilistic models (DPMs) to refine the mean estimation of…

Artificial Intelligence · Computer Science 2023-04-25 Guoqiang Zhang , Niwa Kenta , W. Bastiaan Kleijn

This paper shows that large nonparametric classes of conditional multivariate densities can be approximated in the Kullback--Leibler distance by different specifications of finite mixtures of normal regressions in which normal means and…

Statistics Theory · Mathematics 2010-10-05 Andriy Norets

Debiased machine learning (DML) offers an attractive way to estimate treatment effects in observational settings, where identification of causal parameters requires a conditional independence or unconfoundedness assumption, since it allows…

Econometrics · Economics 2022-06-16 Victor Quintas-Martinez

Popular deep learning frameworks require users to fine-tune their memory usage so that the training data of a deep neural network (DNN) fits within the GPU physical memory. Prior work tries to address this restriction by virtualizing the…

Machine Learning · Computer Science 2017-05-05 Minsoo Rhu , Mike O'Connor , Niladrish Chatterjee , Jeff Pool , Stephen W. Keckler

Debiased machine learning estimators for smooth functionals in nonparametric models can exhibit substantial variability and instability, often leading practitioners to instead rely on parametric or semiparametric working models. Such…

Methodology · Statistics 2026-03-20 Lars van der Laan , Marco Carone , Alex Luedtke , Mark van der Laan

A grand challenge in machine learning is the development of computational algorithms that match or outperform humans in perceptual inference tasks that are complicated by nuisance variation. For instance, visual object recognition involves…

Machine Learning · Statistics 2015-04-03 Ankit B. Patel , Tan Nguyen , Richard G. Baraniuk

This paper introduces Discrete Markov Probabilistic Models (DMPMs), a novel discrete diffusion algorithm for discrete data generation. The algorithm operates in discrete bit space, where the noising process is a continuous-time Markov chain…

Machine Learning · Statistics 2025-10-09 Le-Tuyet-Nhi Pham , Dario Shariatian , Antonio Ocello , Giovanni Conforti , Alain Durmus

The goal of this thesis is to improve our understanding of the internal mechanisms by which deep artificial neural networks create meaningful representations and are able to generalize. We focus on the challenge of characterizing the…

Machine Learning · Computer Science 2025-10-29 Diego Doimo

Contextual Markov decision processes (CMDPs) describe a class of reinforcement learning problems in which the transition kernels and reward functions can change over time with different MDPs indexed by a context variable. While CMDPs serve…

Machine Learning · Computer Science 2024-02-06 Junze Deng , Yuan Cheng , Shaofeng Zou , Yingbin Liang

Integrating deep learning with latent state space models has the potential to yield temporal models that are powerful, yet tractable and interpretable. Unfortunately, current models are not designed to handle missing data or multiple data…

Machine Learning · Computer Science 2019-11-25 Tan Zhi-Xuan , Harold Soh , Desmond C. Ong

Deep metric learning (DML) aims to minimize empirical expected loss of the pairwise intra-/inter- class proximity violations in the embedding space. We relate DML to feasibility problem of finite chance constraints. We show that minimizer…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Yeti Z. Gurbuz , Ogul Can , A. Aydin Alatan

Deep neural networks (DNNs) frequently contain far more weights, represented at a higher precision, than are required for the specific task which they are trained to perform. Consequently, they can often be compressed using techniques such…

Machine Learning · Computer Science 2020-12-03 Vinu Joseph , Saurav Muralidharan , Animesh Garg , Michael Garland , Ganesh Gopalakrishnan

We present an approach to deep estimation of discrete conditional probability distributions. Such models have several applications, including generative modeling of audio, image, and video data. Our approach combines two main techniques:…

Machine Learning · Statistics 2017-03-01 Wesley Tansey , Karl Pichotta , James G. Scott

In recent years, pattern analysis plays an important role in data mining and recognition, and many variants have been proposed to handle complicated scenarios. In the literature, it has been quite familiar with high dimensionality of data…

Machine Learning · Computer Science 2018-11-09 Miao Cheng , Zunren Liu , Hongwei Zou , Ah Chung Tsoi

Machine learning for scientific applications faces the challenge of limited data. We propose a framework that leverages a priori known physics to reduce overfitting when training on relatively small datasets. A deep neural network is…

Machine Learning · Computer Science 2019-11-22 Jonathan B. Freund , Jonathan F. MacArt , Justin Sirignano

This work introduces a novel deep learning-based architecture, termed the Deep Belief Markov Model (DBMM), which provides efficient, model-formulation agnostic inference in Partially Observable Markov Decision Process (POMDP) problems. The…

Machine Learning · Computer Science 2025-03-18 Giacomo Arcieri , Konstantinos G. Papakonstantinou , Daniel Straub , Eleni Chatzi

Markov state models (MSMs) have been successful in computing metastable states, slow relaxation timescales and associated structural changes, and stationary or kinetic experimental observables of complex molecules from large amounts of…

Chemical Physics · Physics 2015-06-17 Frank Noe , Hao Wu , Jan-Hendrik Prinz , Nuria Plattner
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