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Prognoses of Traumatic Brain Injury (TBI) outcomes are neither easily nor accurately determined from clinical indicators. This is due in part to the heterogeneity of damage inflicted to the brain, ultimately resulting in diverse and complex…

Class-incremental learning (CIL) in medical image-guided diagnosis requires retaining prior diagnostic knowledge while adapting to newly emerging disease categories, which is critical for scalable clinical deployment. This problem is…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Xinyao Wu , Zhe Xu , Cheng Chen , Jiawei Ma , Yefeng Zheng , Raymond Kai-yu Tong

Inevitable domain and task discrepancies in real-world scenarios can impair the generalization performance of the pre-trained deep models for medical data. Therefore, we audaciously propose that we should build a general-purpose medical AI…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Huahui Yi , Ziyuan Qin , Qicheng Lao , Wei Xu , Zekun Jiang , Dequan Wang , Shaoting Zhang , Kang Li

Large-scale population-based studies in medicine are a key resource towards better diagnosis, monitoring, and treatment of diseases. They also serve as enablers of clinical decision support systems, in particular Computer Aided Diagnosis…

Machine Learning · Computer Science 2022-03-01 Gerome Vivar , Anees Kazi , Hendrik Burwinkel , Andreas Zwergal , Nassir Navab , Seyed-Ahmad Ahmadi

Body Dysmorphic Disorder (BDD) is a highly prevalent and frequently underdiagnosed condition characterized by persistent, intrusive preoccupations with perceived defects in physical appearance. In this extended analysis, we employ multiple…

Machine Learning · Computer Science 2025-03-17 Omar Costilla-Reyes , Morgan Talbot

Decentralized Federated Learning (DFL), a paradigm for managing big data in a privacy-preserved manner, is still vulnerable to poisoning attacks where malicious clients tamper with data or models. Current defense methods often assume…

Cryptography and Security · Computer Science 2024-11-13 Chao Feng , Alberto Huertas Celdrán , Zien Zeng , Zi Ye , Jan von der Assen , Gerome Bovet , Burkhard Stiller

Health management has become a primary problem as new kinds of diseases and complex symptoms are introduced to a rapidly growing modern society. Building a better and smarter healthcare infrastructure is one of the ultimate goals of a smart…

Machine Learning · Computer Science 2025-03-24 Chu Myaet Thwal , Kyi Thar , Ye Lin Tun , Choong Seon Hong

Estimating model parameters is a crucial step in mathematical modelling and typically involves minimizing the disagreement between model predictions and experimental data. This calibration data can change throughout a study, particularly if…

Quantitative Methods · Quantitative Biology 2023-11-03 Tyler Cassidy

Clinicians usually combine information from multiple sources to achieve the most accurate diagnosis, and this has sparked increasing interest in leveraging multimodal deep learning for diagnosis. However, in real clinical scenarios, due to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Kai Han , Chongwen Lyu , Lele Ma , Chengxuan Qian , Siqi Ma , Zheng Pang , Jun Chen , Zhe Liu

We introduce Matched Machine Learning, a framework that combines the flexibility of machine learning black boxes with the interpretability of matching, a longstanding tool in observational causal inference. Interpretability is paramount in…

Methodology · Statistics 2023-04-05 Marco Morucci , Cynthia Rudin , Alexander Volfovsky

Learning-to-defer is a framework to automatically defer decision-making to a human expert when ML-based decisions are deemed unreliable. Existing learning-to-defer frameworks are not designed for sequential settings. That is, they defer at…

Machine Learning · Computer Science 2022-12-06 Shalmali Joshi , Sonali Parbhoo , Finale Doshi-Velez

Deep learning has revolutionized biomedical research by providing sophisticated methods to handle complex, high-dimensional data. Multimodal deep learning (MDL) further enhances this capability by integrating diverse data types such as…

Machine Learning · Computer Science 2026-03-13 Valerio Guarrasi , Fatih Aksu , Camillo Maria Caruso , Francesco Di Feola , Aurora Rofena , Filippo Ruffini , Paolo Soda

Leveraging multimodal information from Magnetic Resonance Imaging (MRI) plays a vital role in lesion segmentation, especially for brain tumors. However, in clinical practice, multimodal MRI data are often incomplete, making it challenging…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Yulong Zou , Bo Liu , Cun-Jing Zheng , Yuan-ming Geng , Siyue Li , Qiankun Zuo , Shuihua Wang , Yudong Zhang , Jin Hong

One of the most well-established applications of machine learning is in deciding what content to show website visitors. When observation data comes from high-velocity, user-generated data streams, machine learning methods perform a…

This paper addresses the challenges posed by the unstructured nature and high-dimensional semantic complexity of electronic health record texts. A deep learning method based on attention mechanisms is proposed to achieve unified modeling…

Computation and Language · Computer Science 2025-07-03 Ting Xu , Xiaoxiao Deng , Xiandong Meng , Haifeng Yang , Yan Wu

Machine learning in medical imaging during clinical routine is impaired by changes in scanner protocols, hardware, or policies resulting in a heterogeneous set of acquisition settings. When training a deep learning model on an initial…

Computer Vision and Pattern Recognition · Computer Science 2022-03-16 Matthias Perkonigg , Johannes Hofmanninger , Christian Herold , Helmut Prosch , Georg Langs

Modeling disease progression through multiple stages is critical for clinical decision-making for chronic diseases, e.g., cancer, diabetes, chronic kidney diseases, and so on. Existing approaches often model the disease progression as a…

Machine Learning · Computer Science 2025-03-04 Haoyu Yang , Sanjoy Dey , Pablo Meyer

Background: Identifying new indications for approved drugs is a complex and time-consuming process that requires extensive knowledge of pharmacology, clinical data, and advanced computational methods. Recently, deep learning (DL) methods…

Machine Learning · Computer Science 2025-11-13 Shuting Jin , Yi Jiang , Yimin Liu , Tengfei Ma , Dongsheng Cao , Leyi Wei , Xiangrong Liu , Xiangxiang Zeng

Image-based precision medicine aims to personalize treatment decisions based on an individual's unique imaging features so as to improve their clinical outcome. Machine learning frameworks that integrate uncertainty estimation as part of…

Machine Learning · Computer Science 2023-08-11 Joshua Durso-Finley , Jean-Pierre Falet , Raghav Mehta , Douglas L. Arnold , Nick Pawlowski , Tal Arbel

Intelligent learning diagnosis is a critical engine of intelligent tutoring systems, which aims to estimate learners' current knowledge mastery status and predict their future learning performance. The significant challenge with traditional…

Artificial Intelligence · Computer Science 2023-06-14 Zhifeng Wang , Wenxing Yan , Chunyan Zeng , Shi Dong