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Domain-specific large language models (LLMs), typically developed by fine-tuning a pre-trained general-purpose LLM on specialized datasets, represent a significant advancement in applied AI. A common strategy in LLM fine-tuning is…

Machine Learning · Computer Science 2026-01-08 Jing-Cheng Pang , Liu Sun , Chang Zhou , Xian Tang , Haichuan Ma , Kun Jiang , Jianlong Wang , Kai Zhang , Sijie Wu , Haoran Cai , Chenwei Wu , Xubin Li , Xin Chen

Objective: Machine learning techniques have been used extensively for 12-lead electrocardiogram (ECG) analysis. For physiological time series, deep learning (DL) superiority to feature engineering (FE) approaches based on domain knowledge…

Machine Learning · Computer Science 2022-07-19 Eran Zvuloni , Jesse Read , Antônio H. Ribeiro , Antonio Luiz P. Ribeiro , Joachim A. Behar

Electrocardiogram (ECG) is a widely used reliable, non-invasive approach for cardiovascular disease diagnosis. With the rapid growth of ECG examinations and the insufficiency of cardiologists, accurate and automatic diagnosis of ECG signals…

Machine Learning · Computer Science 2020-10-21 Dongdong Zhang , Xiaohui Yuan , Ping Zhang

Conventional planning objectives in optimization of intensity-modulated radiotherapy treatment (IMRT) plans are designed to minimize the violation of dose-volume histogram (DVH) thresholds using penalty functions. Although successful in…

Medical Physics · Physics 2023-07-19 Lovisa Engberg , Kjell Eriksson , Anders Forsgren , Björn Hårdemark

Automated data augmentation, which aims at engineering augmentation policy automatically, recently draw a growing research interest. Many previous auto-augmentation methods utilized a Density Matching strategy by evaluating policies in…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Jianwei Zhang , Dong Li , Lituan Wang , Lei Zhang

Purpose: To evaluate automated multicriteria optimization (MCO)-- designed for intensity modulated radiation therapy (IMRT), but invoked with limited segmentation -- to efficiently produce high quality 3D conformal treatment (3D-CRT) plans.…

Medical Physics · Physics 2014-02-03 Fazal Khan , David Craft

The treatment planning process for patients with head and neck (H&N) cancer is regarded as one of the most complicated due to large target volume, multiple prescription dose levels, and many radiation-sensitive critical structures near the…

Medical Physics · Physics 2019-03-27 Dan Nguyen , Xun Jia , David Sher , Mu-Han Lin , Zohaib Iqbal , Hui Liu , Steve Jiang

Electronic Health Records (EHRs) offer considerable potential for clinical prediction, but their complexity and heterogeneity challenge traditional machine learning. Domain-specific EHR foundation models trained on unlabeled EHR data have…

Differential learning rate (DLR), a technique that applies different learning rates to different model parameters, has been widely used in deep learning and achieved empirical success via its various forms. For example, parameter-efficient…

Machine Learning · Computer Science 2025-05-20 Shiyun Xu , Zhiqi Bu , Yiliang Zhang , Ian Barnett

Advances in deep learning systems have allowed large models to match or surpass human accuracy on a number of skills such as image classification, basic programming, and standardized test taking. As the performance of the most capable…

Machine Learning · Computer Science 2024-06-10 Sarah Pratt , Seth Blumberg , Pietro Kreitlon Carolino , Meredith Ringel Morris

Deep learning (DL) research yields accuracy and product improvements from both model architecture changes and scale: larger data sets and models, and more computation. For hardware design, it is difficult to predict DL model changes.…

Machine Learning · Computer Science 2019-09-05 Joel Hestness , Newsha Ardalani , Greg Diamos

Automated segmentation of anatomical structures is a crucial step in image analysis. For lung segmentation in computed tomography, a variety of approaches exist, involving sophisticated pipelines trained and validated on different datasets.…

Image and Video Processing · Electrical Eng. & Systems 2020-08-21 Johannes Hofmanninger , Florian Prayer , Jeanny Pan , Sebastian Rohrich , Helmut Prosch , Georg Langs

The healthcare sector has experienced a rapid accumulation of digital data recently, especially in the form of electronic health records (EHRs). EHRs constitute a precious resource that IS researchers could utilize for clinical applications…

Machine Learning · Computer Science 2024-11-06 Thiti Suttaket , L Vivek Harsha Vardhan , Stanley Kok

Statistical analysis of magnetic resonance imaging (MRI) can help radiologists to detect pathologies that are otherwise likely to be missed. Deep learning (DL) has shown promise in modeling complex spatial data for brain anomaly detection.…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Victor Saase , Holger Wenz , Thomas Ganslandt , Christoph Groden , Máté E. Maros

We demonstrate the application of mixture density networks (MDNs) in the context of automated radiation therapy treatment planning. It is shown that an MDN can produce good predictions of dose distributions as well as reflect uncertain…

Medical Physics · Physics 2021-07-06 Viktor Nilsson , Hanna Gruselius , Tianfang Zhang , Geert De Kerf , Michaël Claessens

Direct Preference Optimization (DPO) has emerged as an effective approach for aligning large language models (LLMs) with human preferences. However, its performance is highly dependent on the quality of the underlying human preference data.…

Machine Learning · Computer Science 2026-03-10 Zixuan Huang , Yikun Ban , Lean Fu , Xiaojie Li , Zhongxiang Dai , Jianxin Li , Deqing Wang

Longitudinal analysis has great potential to reveal developmental trajectories and monitor disease progression in medical imaging. This process relies on consistent and robust joint 4D segmentation. Traditional techniques are dependent on…

Machine Learning · Computer Science 2019-06-19 Malav Bateriwala , Pierrick Bourgeat

Branch prediction is an architectural feature that speeds up the execution of branch instruction on pipeline processors and reduces the cost of branching. Recent advancements of Deep Learning (DL) in the post Moore's Law era is accelerating…

Hardware Architecture · Computer Science 2022-01-03 Rinu Joseph

This study addresses the challenge of noise in training datasets for Direct Preference Optimization (DPO), a method for aligning Large Language Models (LLMs) with human preferences. We categorize noise into pointwise noise, which includes…

Machine Learning · Computer Science 2025-04-21 Junkang Wu , Yuexiang Xie , Zhengyi Yang , Jiancan Wu , Jiawei Chen , Jinyang Gao , Bolin Ding , Xiang Wang , Xiangnan He

Automated diagnostic assistants in healthcare necessitate accurate AI models that can be trained with limited labeled data, can cope with severe class imbalances and can support simultaneous prediction of multiple disease conditions. To…

Computer Vision and Pattern Recognition · Computer Science 2021-02-11 Deepta Rajan , Jayaraman J. Thiagarajan , Alexandros Karargyris , Satyananda Kashyap