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We review the mathematical formalism underlying the modelling of stochasticity in biological systems. Beginning with a description of the system in terms of its basic constituents, we derive the mesoscopic equations governing the dynamics…

Populations and Evolution · Quantitative Biology 2012-11-05 Alan J. McKane , Tommaso Biancalani , Tim Rogers

One of the most important challenges in mathematical neuroscience is to properly illustrate the stochastic nature of neurons. Among different approaches, the noisy leaky integrate-and-fire and the escape rate models are probably the most…

Analysis of PDEs · Mathematics 2017-02-07 Grégory Dumont , Jacques Henry , Carmen Oana Tarniceriu

Although recent neurophysiological experiments suggest that synchronous neural activity is involved in some perceptual and cognitive processes, the functional role of such coherent neuronal behavior is not well understood. As a first step…

Neurons and Cognition · Quantitative Biology 2007-05-23 Takaaki Aoki , Toshio Aoyagi

In neuroscience, learning and memory are usually associated to long-term changes of neuronal connectivity. In this context, synaptic plasticity refers to the set of mechanisms driving the dynamics of neuronal connections, called {\em…

Probability · Mathematics 2021-06-10 Philippe Robert , Gaetan Vignoud

$\textbf{Formal version available at}$ https://cell.com/patterns/fulltext/S2666-3899(23)00200-3 Networks of spiking neurons underpin the extraordinary information-processing capabilities of the brain and have become pillar models in…

Neural and Evolutionary Computing · Computer Science 2023-09-18 Gehua Ma , Rui Yan , Huajin Tang

We consider a model of a square-wave bursting neuron residing in the regime of tonic spiking. Upon introduction of small stochastic forcing, the model generates irregular bursting. The statistical properties of the emergent bursting…

Adaptation and Self-Organizing Systems · Physics 2008-11-11 Pawel Hitczenko , Georgi S. Medvedev

Our brain is a complex information processing network in which the nervous system receives information from the environment to quickly react to incoming events or learns from experience to sharp our memory. In the nervous system, the brain…

Neurons and Cognition · Quantitative Biology 2022-06-20 Thi Kim Thoa Thieu , Roderick Melnik

One step in the conventional analysis of extracellularly recorded neuronal data is spike sorting, which separates electrical signal into action potentials from different neurons. Because spike sorting involves human judgment, it can be…

Neurons and Cognition · Quantitative Biology 2007-05-23 Artur Luczak , Nandakumar S. Narayanan

We present a first-order non-homogeneous Markov model for the interspike-interval density of a continuously stimulated spiking neuron. The model allows the conditional interspike-interval density and the stationary interspike-interval…

Neurons and Cognition · Quantitative Biology 2012-08-15 J. Tapson , C. Jin , A. van Schaik , R. Etienne-Cummings

At an optimal value of the noise intensity, the maximum variability in rebound burst durations is observed and referred to as a response stochastic incoherence. A general mechanism underlying this phenomenon is given, being different from…

Biological Physics · Physics 2010-03-23 Marzena Ciszak

The conventional impedance profile of a neuron can identify the presence of resonance and other properties of the neuronal response to oscillatory inputs, such as nonlinear response amplifications, but it cannot distinguish other nonlinear…

Neurons and Cognition · Quantitative Biology 2019-10-24 Rodrigo F. O. Pena , Vinicius Lima , Renan O. Shimoura , Cesar C. Ceballos , Horacio G. Rotstein , Antonio C. Roque

Self-sustained activity in the brain is observed in the absence of external stimuli and contributes to signal propagation, neural coding, and dynamic stability. It also plays an important role in cognitive processes. In this work, by means…

Subjective tinnitus (ST) is generally assumed to be a consequence of hearing loss (HL). In animal studies acoustic trauma can lead to behavioral signs of ST, in human studies ST patients without increased hearing thresholds were found to…

Quantitative Methods · Quantitative Biology 2016-03-16 Patrick Krauss , Konstantin Tziridis , Achim Schilling , Claus Metzner , Holger Schulze

We propose a new model based on the Ising model with the aim to study synaptic plasticity phenomena in neural networks. It is today well established in biology that the synapses or connections between certain types of neurons are…

Disordered Systems and Neural Networks · Physics 2016-07-22 Eugene Pechersky , Guillem Via , Anatoly Yambartsev

Spiking neural networks (SNNs) are distributed trainable systems whose computing elements, or neurons, are characterized by internal analog dynamics and by digital and sparse synaptic communications. The sparsity of the synaptic spiking…

Machine Learning · Computer Science 2020-01-08 Hyeryung Jang , Osvaldo Simeone , Brian Gardner , André Grüning

Even when driven by the same stimulus, neuronal responses are well-known to exhibit a striking level of spiking variability. In-vivo electrophysiological recordings also reveal a surprisingly large degree of variability at the subthreshold…

Neurons and Cognition · Quantitative Biology 2025-03-19 Logan A. Becker , Francois Baccelli , Thibaud Taillefumier

Chaos provides many interesting properties that can be used to achieve computational tasks. Such properties are sensitivity to initial conditions, space filling, control and synchronization. Chaotic neural models have been devised to…

Neural and Evolutionary Computing · Computer Science 2015-01-12 M. Alhawarat , T. Olde Scheper , N. T. Crook

The spiking activity of neocortical neurons exhibits a striking level of variability, even when these networks are driven by identical stimuli. The approximately Poisson firing of neurons has led to the hypothesis that these neural networks…

Neurons and Cognition · Quantitative Biology 2023-12-29 Logan A. Becker , Baowang Li , Nicholas J. Priebe , Eyal Seidemann , Thibaud Taillefumier

Spiking Neural Networks (SNNs), recognized as the third generation of neural networks, are known for their bio-plausibility and energy efficiency, especially when implemented on neuromorphic hardware. However, the majority of existing…

Neural and Evolutionary Computing · Computer Science 2024-07-02 Yi Jiang , Sen Lu , Abhronil Sengupta

A stochastic model of excitatory and inhibitory interactions which bears universality traits is introduced and studied. The endogenous component of noise, stemming from finite size corrections, drives robust inter-nodes correlations, that…

Disordered Systems and Neural Networks · Physics 2017-08-16 Clement Zankoc , Duccio Fanelli , Francesco Ginelli , Roberto Livi