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This paper derives the nonparametric maximum likelihood estimator (NPMLE) of a distribution function from observations which are subject to both bias and censoring. The NPMLE is obtained by a simple EM algorithm which is an extension of the…

Statistics Theory · Mathematics 2007-08-22 Micha Mandel

Anomaly detection when observing a large number of data streams is essential in a variety of applications, ranging from epidemiological studies to monitoring of complex systems. High-dimensional scenarios are usually tackled with…

Methodology · Statistics 2025-12-18 Ivo V. Stoepker , Rui M. Castro , Ery Arias-Castro , Edwin van den Heuvel

It is frequently of interest to jointly analyze multiple sequences of multiple tests in order to identify simultaneous signals, defined as features tested in multiple studies whose test statistics are non-null in each. In many problems,…

Methodology · Statistics 2019-01-16 Sihai Dave Zhao , Yet Tien Nguyen

Admixture models are a ubiquitous approach to capture latent population structure in genetic samples. Despite the widespread application of admixture models, little thought has been devoted to the quality of the model fit or the accuracy of…

Methodology · Statistics 2015-11-12 David Mimno , David M Blei , Barbara E Engelhardt

Biometric recognition is used across a variety of applications from cyber security to border security. Recent research has focused on ensuring biometric performance (false negatives and false positives) is fair across demographic groups.…

Methodology · Statistics 2022-08-24 Michael Schuckers , Sandip Purnapatra , Kaniz Fatima , Daqing Hou , Stephanie Schuckers

We study the Nonparametric Maximum Likelihood Estimator (NPMLE) for estimating Gaussian location mixture densities in $d$-dimensions from independent observations. Unlike usual likelihood-based methods for fitting mixtures, NPMLEs are based…

Statistics Theory · Mathematics 2019-07-09 Sujayam Saha , Adityanand Guntuboyina

We study the problem of testing the goodness of fit of categorical count data to a Poisson distribution uniform over the categories, against a class of alternatives defined by excluding an $\ell_p$ ball, $p \leq 2$, of radius $\epsilon$…

Statistics Theory · Mathematics 2025-12-16 Alon Kipnis

Covariate measurement error in regression analysis is an important issue that has been studied extensively under the classical additive and the Berkson error models. Here, we consider cases where covariates are derived from tumor tissue…

This article concerns testing for equality of distribution between groups. We focus on screening variables with shared distributional features such as common support, modes and patterns of skewness. We propose a Bayesian testing method…

Methodology · Statistics 2016-02-19 Eric F. Lock , David B. Dunson

Linear mixed models (LMMs) are a powerful and established tool for studying genotype-phenotype relationships. A limiting assumption of LMMs is that the residuals are Gaussian distributed, a requirement that rarely holds in practice.…

Genomics · Quantitative Biology 2014-08-10 Nicolo Fusi , Christoph Lippert , Neil D. Lawrence , Oliver Stegle

We provide finite-sample distribution approximations, that are uniform in the parameter, for inference in linear mixed models. Focus is on variances and covariances of random effects in cases where existing theory fails because their…

Statistics Theory · Mathematics 2025-07-29 Karl Oskar Ekvall , Matteo Bottai

Motivated by problems in data clustering, we establish general conditions under which families of nonparametric mixture models are identifiable, by introducing a novel framework involving clustering overfitted \emph{parametric} (i.e.…

Statistics Theory · Mathematics 2020-02-19 Bryon Aragam , Chen Dan , Eric P. Xing , Pradeep Ravikumar

Non-negative matrix factorization (NMF) is widely used as a feature extraction technique for matrices with non-negative entries, such as image data, purchase histories, and other types of count data. In NMF, a non-negative matrix is…

Computation · Statistics 2026-01-01 Ryo Ohashi , Hiroyasu Abe , Fumitake Sakaori

We introduce a Bayesian approach to predictive density calibration and combination that accounts for parameter uncertainty and model set incompleteness through the use of random calibration functionals and random combination weights.…

Applications · Statistics 2016-10-26 Federico Bassetti , Roberto Casarin , Francesco Ravazzolo

Through spectral unmixing, hyperspectral imaging (HSI) in fluorescence-guided brain tumor surgery has enabled detection and classification of tumor regions invisible to the human eye. Prior unmixing work has focused on determining a minimal…

Image and Video Processing · Electrical Eng. & Systems 2024-02-01 David Black , Benoit Liquet , Sadahiro Kaneko , Antonio Di leva , Walter Stummer , Eric Suero Molina

This paper considers the problem of comparing two processes with panel data. A nonparametric test is proposed for detecting a monotone change in the link between the two process distributions. The test statistic is of CUSUM type, based on…

Statistics Theory · Mathematics 2011-05-04 Denys Pommeret , Mohamed Boutahar , Badih Ghattas

The large-sample properties of likelihood-based statistical inference under mixture models have received much attention from statisticians. Although the consistency of the nonparametric MLE is regarded as a standard conclusion, many…

Statistics Theory · Mathematics 2016-07-06 Jiahua Chen

We show that postselection offers a nonclassical advantage in metrology. In every parameter-estimation experiment, the final measurement or the postprocessing incurs some cost. Postselection can improve the rate of Fisher information (the…

Two-component mixture models are particularly useful for identifying differentially expressed genes, but their performance can deteriorate markedly when the alternative distribution departs from parametric assumptions or symmetry. We…

Methodology · Statistics 2026-03-18 Sangkon Oh , Geoffrey J. McLachlan

The synthetic control method is often applied to problems with one treated unit and a small number of control units. A common inferential task in this setting is to test null hypotheses regarding the average treatment effect on the treated.…

Methodology · Statistics 2025-04-22 Lihua Lei , Timothy Sudijono