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We propose the density ratio permutation test, a hypothesis test that assesses whether the ratio between two densities is proportional to a known function based on independent samples from each distribution. The test uses an efficient…

Methodology · Statistics 2026-01-14 Alberto Bordino , Thomas B. Berrett

Mixed linear models are commonly used in repeated measures studies. They account for the dependence amongst observations obtained from the same experimental unit. Oftentimes, the number of observations is small, and it is thus important to…

Methodology · Statistics 2011-08-05 Tatiane F. N. Melo , Silvia L. P. Ferrari , Francisco Cribari-Neto

We exploit a suitable moment-based characterization of the mixture of Poisson distribution for developing Bayesian inference for the unknown size of a finite population whose units are subject to multiple occurrences during an enumeration…

Methodology · Statistics 2018-06-19 Danilo Alunni Fegatelli , Luca Tardella

Nonparametric empirical Bayes methods provide a flexible and attractive approach to high-dimensional data analysis. One particularly elegant empirical Bayes methodology, involving the Kiefer-Wolfowitz nonparametric maximum likelihood…

Methodology · Statistics 2014-07-11 Lee H. Dicker , Sihai D. Zhao

Evolve and resequence studies provide a popular approach to simulate evolution in the lab and explore its genetic basis. In this context, the chi-square test, Fishers exact test, as well as the Cochran-Mantel-Haenszel test are commonly used…

Applications · Statistics 2019-02-22 Kerstin Spitzer , Marta Pelizzola , Andreas Futschik

The Friedman test has been extensively applied as a nonparametric alternative to the conventional F procedure for comparing treatment effects in randomized complete block designs. A chi-square distribution provides a convenient…

Methodology · Statistics 2025-03-24 Show-Li Jan , Gwowen Shieh

Since its introduction in 1950, Fisher's dispersion test has become a standard means of deciding whether or not count data follow the Poisson distribution. The test is based on a characteristic property of the Poisson distribution, and…

Applications · Statistics 2025-03-21 Erekle Khurodze , Leigh A Roberts

We consider the problem of estimating a mixture of power series distributions with infinite support, to which belong very well-known models such as Poisson, Geometric, Logarithmic or Negative Binomial probability mass functions. We consider…

Statistics Theory · Mathematics 2025-08-04 Fadoua Balabdaoui , Harald Besdziek , Yong Wang

Learning distributions over permutations is a fundamental problem in machine learning, with applications in ranking, combinatorial optimization, structured prediction, and data association. Existing methods rely on mixtures of parametric…

Machine Learning · Computer Science 2025-06-02 Daniel Severo , Brian Karrer , Niklas Nolte

Permutation tests are widely used in statistics, providing a finite-sample guarantee on the type I error rate whenever the distribution of the samples under the null hypothesis is invariant to some rearrangement. Despite its increasing…

Statistics Theory · Mathematics 2022-05-26 Ilmun Kim , Sivaraman Balakrishnan , Larry Wasserman

Gaussian mixture models form a flexible and expressive parametric family of distributions that has found applications in a wide variety of applications. Unfortunately, fitting these models to data is a notoriously hard problem from a…

Statistics Theory · Mathematics 2023-01-05 Yuling Yan , Kaizheng Wang , Philippe Rigollet

Introduced by Kiefer and Wolfowitz \cite{KW56}, the nonparametric maximum likelihood estimator (NPMLE) is a widely used methodology for learning mixture odels and empirical Bayes estimation. Sidestepping the non-convexity in mixture…

Statistics Theory · Mathematics 2020-09-08 Yury Polyanskiy , Yihong Wu

In applications such as gene regulatory network analysis based on single-cell RNA sequencing data, samples often come from a mixture of different populations and each population has its own unique network. Available graphical models often…

Methodology · Statistics 2022-12-08 Junjie Tang , Changhu Wang , Feiyi Xiao , Ruibin Xi

In large scale genetic association studies, a primary aim is to test for association between genetic variants and a disease outcome. The variants of interest are often rare, and appear with low frequency among subjects. In this situation,…

Methodology · Statistics 2017-12-20 Arjun Sondhi , Kenneth Martin Rice

We propose a general modeling framework for marked Poisson processes observed over time or space. The modeling approach exploits the connection of the nonhomogeneous Poisson process intensity with a density function. Nonparametric Dirichlet…

Methodology · Statistics 2011-11-02 Matthew A. Taddy , Athanasios Kottas

In this article we survey properties of mixed Poisson distributions and probabilistic aspects of the Stirling transform: given a non-negative random variable $X$ with moment sequence $(\mu_s)_{s\in\mathbb{N}}$ we determine a discrete random…

Combinatorics · Mathematics 2014-09-12 Markus Kuba , Alois Panholzer

We continue studies of the uncertainty quantification problem in emission tomographies such as PET or SPECT when additional multimodal data (e.g., anatomical MRI images) are available. To solve the aforementioned problem we adapt the…

Machine Learning · Statistics 2021-12-03 Fedor Goncharov , Éric Barat , Thomas Dautremer

We propose a new test to address the nonparametric Behrens-Fisher problem involving different distribution functions in the two samples. Our procedure tests the null hypothesis $\mathcal{H}_0: \theta = \frac{1}{2}$, where $\theta = P(X<Y) +…

Methodology · Statistics 2025-04-09 Stephen Schüürhuis , Frank Konietschke , Edgar Brunner

In most of the recent immunological literature the differences across antigen receptor populations are examined via non-parametric statistical measures of species overlap and diversity borrowed from ecological studies. While this approach…

Biomolecules · Quantitative Biology 2010-03-05 Grzegorz A. Rempala , Michal Seweryn , Leszek Ignatowicz

Nonparametric estimation of a mixing distribution based on data coming from a mixture model is a challenging problem. Beyond estimation, there is interest in uncertainty quantification, e.g., confidence intervals for features of the mixing…

Methodology · Statistics 2019-06-14 Vaidehi Dixit , Ryan Martin