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Reconstructing multiple molecularly defined neurons from individual brains and across multiple brain regions can reveal organizational principles of the nervous system. However, high resolution imaging of the whole brain is a technically…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 James Gornet , Kannan Umadevi Venkataraju , Arun Narasimhan , Nicholas Turner , Kisuk Lee , H. Sebastian Seung , Pavel Osten , Uygar Sümbül

Automated sample preparation and electron microscopy enables acquisition of very large image data sets. These technical advances are of special importance to the field of neuroanatomy, as 3D reconstructions of neuronal processes at the nm…

In this paper, it is shown that an auto-encoder using optimal reconstruction significantly outperforms a conventional auto-encoder. Optimal reconstruction uses the conditional mean of the input given the features, under a maximum entropy…

Machine Learning · Computer Science 2021-04-16 Paul M Baggenstoss

Traditional voxel-level multiple testing procedures in neuroimaging, mostly $p$-value based, often ignore the spatial correlations among neighboring voxels and thus suffer from substantial loss of power. We extend the…

Applications · Statistics 2016-07-29 Hai Shu , Bin Nan , Robert Koeppe

With the advent of brain imaging techniques and machine learning tools, much effort has been devoted to building computational models to capture the encoding of visual information in the human brain. One of the most challenging brain…

Computer Vision and Pattern Recognition · Computer Science 2021-11-29 Zarina Rakhimberdina , Quentin Jodelet , Xin Liu , Tsuyoshi Murata

Neuron reconstruction is essential to generate exquisite neuron connectivity map for understanding brain function. Despite the significant amount of effect that has been made on automatic reconstruction methods, manual tracing by…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Donghuan Lu , Sujun Zhao , Peng Xie , Kai Ma , Lijuan Liu , Yefeng Zheng

Image reconstruction from undersampled k-space data has been playing an important role for fast MRI. Recently, deep learning has demonstrated tremendous success in various fields and also shown potential to significantly speed up MR…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Dong Liang , Jing Cheng , Ziwen Ke , Leslie Ying

Visual reconstruction algorithms are an interpretive tool that map brain activity to pixels. Past reconstruction algorithms employed brute-force search through a massive library to select candidate images that, when passed through an…

Neurons and Cognition · Quantitative Biology 2023-05-03 Reese Kneeland , Jordyn Ojeda , Ghislain St-Yves , Thomas Naselaris

Hidden Markov models are traditionally decoded by the Viterbi algorithm which finds the highest probability state path in the model. In recent years, several limitations of the Viterbi decoding have been demonstrated, and new algorithms…

Data Structures and Algorithms · Computer Science 2013-08-06 Michal Nánási , Tomáš Vinař , Broňa Brejová

Neuron reconstruction, one of the fundamental tasks in neuroscience, rebuilds neuronal morphology from 3D light microscope imaging data. It plays a critical role in analyzing the structure-function relationship of neurons in the nervous…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Yik San Cheng , Runkai Zhao , Heng Wang , Hanchuan Peng , Weidong Cai

Visual image reconstruction, the decoding of perceptual content from brain activity into images, has advanced significantly with the integration of deep neural networks (DNNs) and generative models. This review traces the field's evolution…

Computer Vision and Pattern Recognition · Computer Science 2025-06-23 Yukiyasu Kamitani , Misato Tanaka , Ken Shirakawa

In a hidden Markov model, the underlying Markov chain is usually hidden. Often, the maximum likelihood alignment (Viterbi alignment) is used as its estimate. Although having the biggest likelihood, the Viterbi alignment can behave very…

Methodology · Statistics 2013-07-31 Kristi Kuljus , Jüri Lember

Large water Cherenkov detectors have shaped our current knowledge of neutrino physics and nucleon decay, and will continue to do so in the foreseeable future. These highly capable detectors allow for directional and topological, as well as…

High Energy Physics - Experiment · Physics 2022-02-04 Mo Jia , Karan Kumar , Liam S. Mackey , Alexander Putra , Cristovao Vilela , Michael J. Wilking , Junjie Xia , Chiaki Yanagisawa , Karan Yang

Reconstruction of neuroanatomy is a fundamental problem in neuroscience. Stochastic expression of colors in individual cells is a promising tool, although its use in the nervous system has been limited due to various sources of variability…

Neurons and Cognition · Quantitative Biology 2017-01-24 Uygar Sümbül , Douglas Roussien , Fei Chen , Nicholas Barry , Edward S. Boyden , Dawen Cai , John P. Cunningham , Liam Paninski

We consider a bivariate, possibly non-homogeneous, finite-state Markov chain $(X,U)=\{(X_t,U_t)\}_{t=1}^n$. We are interested in the marginal process $X$, which typically is not a Markov chain. The goal is to find a realization (path)…

Computation · Statistics 2025-07-28 Oskar Soop , Jüri Lember

In this work, we propose a deep learning approach for parallel magnetic resonance imaging (MRI) reconstruction, termed a variable splitting network (VS-Net), for an efficient, high-quality reconstruction of undersampled multi-coil MR data.…

Image and Video Processing · Electrical Eng. & Systems 2019-07-24 Jinming Duan , Jo Schlemper , Chen Qin , Cheng Ouyang , Wenjia Bai , Carlo Biffi , Ghalib Bello , Ben Statton , Declan P O'Regan , Daniel Rueckert

Recent medical image reconstruction techniques focus on generating high-quality medical images suitable for clinical use at the lowest possible cost and with the fewest possible adverse effects on patients. Recent works have shown…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Shijun Liang , Anish Lahiri , Saiprasad Ravishankar

In this paper we propose a deep learning approach for segmenting sub-cortical structures of the human brain in Magnetic Resonance (MR) image data. We draw inspiration from a state-of-the-art Fully-Convolutional Neural Network (F-CNN)…

Computer Vision and Pattern Recognition · Computer Science 2016-02-08 Mahsa Shakeri , Stavros Tsogkas , Enzo Ferrante , Sarah Lippe , Samuel Kadoury , Nikos Paragios , Iasonas Kokkinos

We report the possibility of using a simple neural network for effortless restoration of low-light images inspired by the retina model, which mimics the neurophysiological principles and dynamics of various types of optical neurons. The…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Yurui Ming , Yuanyuan Liang

Magnetic resonance imaging (MRI) is one of the noninvasive imaging modalities that can produce high-quality images. However, the scan procedure is relatively slow, which causes patient discomfort and motion artifacts in images. Accelerating…

Image and Video Processing · Electrical Eng. & Systems 2023-01-18 Samira Vafay Eslahi , Jian Tao , Jim Ji
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