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Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

Recent advancements in large language models have opened new possibilities for generative molecular drug design. We present Chemlactica and Chemma, two language models fine-tuned on a novel corpus of 110M molecules with computed properties,…

In spite of the strong performance of machine learning (ML) models in radiology, they have not been widely accepted by radiologists, limiting clinical integration. A key reason is the lack of explainability, which ensures that model…

Human-Computer Interaction · Computer Science 2026-04-14 Sara Ketabi , Matthias W. Wagner , Birgit Betina Ertl-Wagner , Greg A. Jamieson , Farzad Khalvati

Machine learning (ML) models have significantly impacted various domains in our everyday lives. While large language models (LLMs) offer intuitive interfaces and versatility, task-specific ML models remain valuable for their efficiency and…

Human-Computer Interaction · Computer Science 2024-12-04 Wataru Kawabe , Yusuke Sugano

Unified Modeling Language (UML) is currently accepted as the standard for modeling (object-oriented) software, and its use is increasing in the aerospace industry. Verification and Validation of complex software developed according to UML…

Large Language Models demonstrate substantial promise for advancing scientific discovery, yet their deployment in disciplines demanding factual precision and specialized domain constraints presents significant challenges. Within molecular…

Machine Learning · Computer Science 2026-02-23 Malikussaid , Hilal Hudan Nuha , Isman Kurniawan

The ever higher complexity of manufacturing systems, continually shortening life cycles of products and their increasing variety, as well as the unstable market situation of the recent years require introducing grater flexibility and…

Computational Engineering, Finance, and Science · Computer Science 2007-05-23 H. Tamaki , V. V. Kryssanov , S. Kitamura

The paper introduces a framework for the evaluation of the encoding of factual scientific knowledge, designed to streamline the manual evaluation process typically conducted by domain experts. Inferring over and extracting information from…

Computation and Language · Computer Science 2024-10-21 Magdalena Wysocka , Oskar Wysocki , Maxime Delmas , Vincent Mutel , Andre Freitas

The growing complexity of cyber-physical systems, particularly in automotive applications, has increased the demand for efficient modeling and cross-domain co-simulation techniques. While SystemC Transaction-Level Modeling (TLM) enables…

Scientific databases aggregate vast amounts of quantitative data alongside descriptive text. In biochemistry, molecule screening assays evaluate candidate molecules' functional responses against disease targets. Unstructured text that…

Machine Learning · Computer Science 2025-11-18 Yifan Deng , Spencer S. Ericksen , Anthony Gitter

Large Language Models (LLMs) have recently demonstrated remarkable performance in general tasks across various fields. However, their effectiveness within specific domains such as drug development remains challenges. To solve these…

Artificial Intelligence · Computer Science 2024-10-16 Tengfei Ma , Xuan Lin , Tianle Li , Chaoyi Li , Long Chen , Peng Zhou , Xibao Cai , Xinyu Yang , Daojian Zeng , Dongsheng Cao , Xiangxiang Zeng

The UML allows us to specify models in a precise, complete and unambiguous manner. In particular, the UML addresses the specification of all important decisions regarding analysis, design and implementation. Although UML is not a visual…

Software Engineering · Computer Science 2010-01-26 S. S. Riaz Ahamed

Simulation models are an absolute necessity in the human and social sciences, which can only very exceptionally use experimental science methods to construct their knowledge. Models enable the simulation of social processes by replacing the…

Computers and Society · Computer Science 2020-01-06 J. Raimbault , D. Pumain

Large Language Models (LLMs) are expected to significantly contribute to patient care, diagnostics, and administrative processes. Emerging biomedical LLMs aim to address healthcare-specific challenges, including privacy demands and…

Computation and Language · Computer Science 2025-10-14 Amin Dada , Marie Bauer , Amanda Butler Contreras , Osman Alperen Koraş , Constantin Marc Seibold , Kaleb E Smith , Jens Kleesiek

We introduce Concept Bottleneck Protein Language Models (CB-pLM), a generative masked language model with a layer where each neuron corresponds to an interpretable concept. Our architecture offers three key benefits: i) Control: We can…

The proliferation of Large Language Models (LLMs) presents transformative potential for healthcare, yet practical deployment is hindered by the absence of frameworks that assess real-world clinical utility. Existing benchmarks test static…

Open large language models (LLMs) have demonstrated improving multilingual capabilities in recent years. In this paper, we present a study of open LLMs for multilingual machine translation (MT) across a range of languages, and investigate…

Computation and Language · Computer Science 2026-02-26 Yuzhe Shang , Pengzhi Gao , Wei Liu , Jian Luan , Jinsong Su

In recent years, the rapid development of Large Language Models (LLMs) has significantly enhanced natural language understanding and human-computer interaction, creating new opportunities in the field of robotics. However, the integration…

Robotics · Computer Science 2026-01-06 Shenqi Lu , Liangwei Zhang

Large language models (LLMs) have made impressive progress in chemistry applications. However, the community lacks an LLM specifically designed for chemistry. The main challenges are two-fold: firstly, most chemical data and scientific…

The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…