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The current global health emergency triggered by the pandemic COVID-19 is one of the greatest challenges mankind face in this generation. Computational simulations have played an important role to predict the development of the current…

Populations and Evolution · Quantitative Biology 2020-06-11 Kok Yew Ng , Meei Mei Gui

Epidemic spread on networks is one of the most studied dynamics in network science and has important implications in real epidemic scenarios. Nonetheless, the dynamics of real epidemics and how it is affected by the underline structure of…

Physics and Society · Physics 2020-09-08 Bnaya Gross , Shlomo Havlin

We consider a behavioral-feedback SIR epidemic model, in which the infection rate depends in feedback on the fractions of susceptible and infected agents, respectively. The considered model allows one to account for endogenous adaptation…

Systems and Control · Electrical Eng. & Systems 2026-02-11 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

This paper analyses the optimal control of infectious disease propagation using a classic susceptible-infected-recovered (SIR) model characterised by permanent immunity and the absence of available vaccines. The control is performed over a…

Optimization and Control · Mathematics 2024-06-12 Rocío Balderrama , Mariana Inés Prieto , Constanza Sánchez de la Vega , Federico Vazquez

The novel coronavirus SARS-CoV-2 and resulting COVID-19 disease have had an unprecedented spread and continue to cause an increasing number of fatalities worldwide. While vaccines are still under development, social distancing, extensive…

Populations and Evolution · Quantitative Biology 2020-07-02 Calvin Tsay , Fernando Lejarza , Mark A. Stadtherr , Michael Baldea

The SARS-CoV-2 infectious outbreak has rapidly spread across the globe and precipitated varying policies to effectuate physical distancing to ameliorate its impact. In this study, we propose a new hybrid machine learning model, SIRNet, for…

Populations and Evolution · Quantitative Biology 2020-04-23 Nicholas Soures , David Chambers , Zachariah Carmichael , Anurag Daram , Dimpy P. Shah , Kal Clark , Lloyd Potter , Dhireesha Kudithipudi

Understanding the dynamics of an epidemic spread is crucial for effective control measures. During the COVID-19 pandemic, quarantines were implemented to minimize infections while mitigating social and economic impacts, raising the question…

Statistical Mechanics · Physics 2024-11-19 Eyal Atias , Michael Assaf

As the COVID19 spreads across the world, prevention measures are becoming the essential weapons to combat the pandemic in the period of crisis. The lockdown measure is the most controversial one as it imposes an overwhelming impact on our…

Physics and Society · Physics 2021-02-12 Yuting Fu , Haitao Xiang , Hanqing Jin , Ning Wang

In real social networks, person-to-person interactions are known to be heterogeneous, which can affect the way a disease spreads through a population, reaches a tipping point in the fraction of infected individuals, and becomes an epidemic.…

Physics and Society · Physics 2020-05-12 Ignacio A. Perez , Paul A. Trunfio , Cristian E. La Rocca , Lidia A. Braunstein

We apply optimal control theory to a generalized SEIR-type model. The proposed system has three controls, representing social distancing, preventive means, and treatment measures to combat the spread of the COVID-19 pandemic. We analyze…

Optimization and Control · Mathematics 2021-12-10 Mohamed Abdelaziz Zaitri , Mohand Ouamer Bibi , Delfim F. M. Torres

The 2019 Novel Corona virus infection (COVID 19) is an ongoing public health emergency of international focus. Significant gaps persist in our knowledge of COVID 19 epidemiology, transmission dynamics, investigation tools and management,…

Physics and Society · Physics 2020-12-01 Anca Radulescu , Cassandra Williams , Kieran Cavanagh

We investigate phase transitions associated with three control methods for epidemics on small world networks. Motivated by the behavior of SARS-CoV-2, we construct a theoretical SIR model of a virus that exhibits presymptomatic,…

Physics and Society · Physics 2020-07-13 Benjamin Braun , Başak Taraktaş , Brian Beckage , Jane Molofsky

In this study, we present an epidemic-controlled SIRD model with two types of control strategies: mask wear and screening. The aim of this study is to minimize the number of deceased keeping a minimal cost of mask advertising and screening.…

Populations and Evolution · Quantitative Biology 2021-09-06 Amira Bouhali , Walid Ben Aribi , Slimane Ben Miled , Amira Kebir

The novel COVID-19 pandemic is a current, major global health threat. Up till now, there is no fully approved pharmacological treatment or a vaccine. In this study, simple mathematical models were employed to examine the dynamics of…

Physics and Society · Physics 2020-12-25 Ahmed S. Elgazzar

The spread of COVID-19 during the initial phase of the first half of 2020 was curtailed to a larger or lesser extent through measures of social distancing imposed by most countries. In this work, we link directly, through machine learning…

Populations and Evolution · Quantitative Biology 2020-08-20 G. D. Barmparis , G. P. Tsironis

In this paper, we introduce a novel modeling framework for incorporating fear of infection and frustration with social distancing into disease dynamics. We show that the resulting SEIR behavior-perception model has three principal modes of…

Populations and Evolution · Quantitative Biology 2020-08-14 Matthew D. Johnston , Bruce Pell

The current COVID-19 pandemic and subsequent lockdowns have highlighted the close and delicate relationship between a country's public health and economic health. Macroeconomic models that use preexisting epidemic models to calculate the…

Physics and Society · Physics 2020-07-01 Erhan Bayraktar , Asaf Cohen , April Nellis

We present a data-driven optimal control approach which integrates the reported partial data with the epidemic dynamics for COVID-19. We use a basic Susceptible-Exposed-Infectious-Recovered (SEIR) model, the model parameters are…

Optimization and Control · Mathematics 2020-12-22 Hailiang Liu , Xuping Tian

The recent COVID-19 pandemic has promoted vigorous scientific activity in an effort to understand, advice and control the pandemic. Data is now freely available at a staggering rate worldwide. Unfortunately, this unprecedented level of…

Applications · Statistics 2024-01-31 Yuansan Liu , Saransh Srivastava , Zuo Huang , Felisa J. Vázquez-Abad

We study the impact of parameter estimation and state measurement errors on a control framework for optimally mitigating the spread of epidemics. We capture the epidemic spreading process using a susceptible-infected-removed (SIR) epidemic…

Systems and Control · Electrical Eng. & Systems 2024-08-08 Baike She , Lei Xin , Shreyas Sundaram , Philip E. Paré