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We study causal inference under case-control and case-population sampling. Specifically, we focus on the binary-outcome and binary-treatment case, where the parameters of interest are causal relative and attributable risks defined via the…

Econometrics · Economics 2023-10-24 Sung Jae Jun , Sokbae Lee

Clinical notes contain an extensive record of a patient's health status, such as smoking status or the presence of heart conditions. However, this detail is not replicated within the structured data of electronic health systems.…

Computation and Language · Computer Science 2020-09-18 Andriy Mulyar , Elliot Schumacher , Masoud Rouhizadeh , Mark Dredze

The case$^2$ study, also referred to as the case-case study design, is a valuable approach for conducting inference for treatment effects. Unlike traditional case-control studies, the case$^2$ design compares treatment in two types of cases…

Methodology · Statistics 2025-03-03 Kan Chen , Ting Ye , Dylan S. Small

Image segmentation enables to extract quantitative measures from scans that can serve as imaging biomarkers for diseases. However, segmentation quality can vary substantially across scans, and therefore yield unfaithful estimates in the…

Image and Video Processing · Electrical Eng. & Systems 2020-11-03 J. Senapati , A. Guha Roy , S. Pölsterl , D. Gutmann , S. Gatidis , C. Schlett , A. Peters , F. Bamberg , C. Wachinger

Healthcare data from patient or population cohorts are often characterized by sparsity, high missingness and relatively small sample sizes. In addition, being able to quantify uncertainty is often important in a medical context. To address…

Machine Learning · Statistics 2025-03-28 H. C. Donker , D. Neijzen , J. de Jong , G. A. Lunter

The hazard ratio is one of the most commonly reported measures of treatment effect in randomised trials, yet the source of much misinterpretation. This point was made clear by (Hernan, 2010) in commentary, which emphasised that the hazard…

Statistics Theory · Mathematics 2018-10-23 Torben Martinussen , Stijn Vansteelandt , Per Kragh Andersen

Health-policy planning requires evidence on the burden that epidemics place on healthcare systems. Multiple, often dependent, datasets provide a noisy and fragmented signal from the unobserved epidemic process including transmission and…

Applications · Statistics 2024-09-11 Alice Corbella , Anne M Presanis , Paul J Birrell , Daniela De Angelis

Electronic patient records (EPRs) produce a wealth of data but contain significant missing information. Understanding and handling this missing data is an important part of clinical data analysis and if left unaddressed could result in bias…

Machine Learning · Computer Science 2024-02-12 Neslihan Suzen , Evgeny M. Mirkes , Damian Roland , Jeremy Levesley , Alexander N. Gorban , Tim J. Coats

Many legal cases require decisions about causality, responsibility or blame, and these may be based on statistical data. However, causal inferences from such data are beset by subtle conceptual and practical difficulties, and in general it…

Statistics Theory · Mathematics 2020-04-28 Philip Dawid , Monica Musio , Rossella Murtas

Clinical robustness is critical to the safe deployment of medical Large Language Models (LLMs), but key questions remain about how LLMs and humans may differ in response to the real-world variability typified by clinical settings. To…

Artificial Intelligence · Computer Science 2025-06-23 Abinitha Gourabathina , Yuexing Hao , Walter Gerych , Marzyeh Ghassemi

The accounts of medical trials provide very detailed information about the patients' health conditions. In contrast, only minimal data are usually given about demographic factors. Yet, some of these factors can have a notable impact on the…

Applications · Statistics 2015-06-16 Bertrand M. Roehner

Detecting testimonial injustice is an essential element of addressing inequities and promoting inclusive healthcare practices, many of which are life-critical. However, using a single demographic factor to detect testimonial injustice does…

Computers and Society · Computer Science 2023-10-31 Kenya S. Andrews , Bhuvani Shah , Lu Cheng

The presence of bacteria or fungi in the bloodstream of patients is abnormal and can lead to life-threatening conditions. A computational model based on a bidirectional long short-term memory artificial neural network, is explored to assist…

Machine Learning · Computer Science 2016-12-06 Leen De Baets , Joeri Ruyssinck , Thomas Peiffer , Johan Decruyenaere , Filip De Turck , Femke Ongenae , Tom Dhaene

The following is a write up of the progress of modeling data from the K12 organization \cite{Riedman_2023}. Data was characterized and investigated for statistically significant factors. The incident data was spilt into three sets: the…

Applications · Statistics 2024-05-29 Robert Hernandez , Linn Carothers

Many serial killers commit tens of murders. At the same time inter-murder intervals can be decades long. This suggests that some serial killers can die of an accident or a disease, having been never caught. We use the distribution of the…

Physics and Society · Physics 2021-09-24 M. V. Simkin , V. P. Roychowdhury

Honour based abuse covers a wide range of family abuse including female genital mutilation and forced marriage. Safeguarding professionals need to identify where abuses are happening in their local community to best support those at risk of…

Applications · Statistics 2024-12-13 Rowland G Seymour , Fabian Hernandez

The object of this paper is to develop a statistical approach to criminal linkage analysis that discovers and groups crime events that share a common offender and prioritizes suspects for further investigation. Bayes factors are used to…

Applications · Statistics 2014-10-10 Michael D. Porter

Cardiovascular disease is the number one cause of death all over the world. Data mining can help to retrieve valuable knowledge from available data from the health sector. It helps to train a model to predict patients' health which will be…

Machine Learning · Computer Science 2020-12-18 Mistura Muibideen , Rajesh Prasad

Accurate identification and categorization of suicidal events can yield better suicide precautions, reducing operational burden, and improving care quality in high-acuity psychiatric settings. Pre-trained language models offer promise for…

Computation and Language · Computer Science 2024-10-07 Zehan Li , Yan Hu , Scott Lane , Salih Selek , Lokesh Shahani , Rodrigo Machado-Vieira , Jair Soares , Hua Xu , Hongfang Liu , Ming Huang

This paper focuses on the Bayesian Network Propensity Score (BNPS), a novel approach for estimating treatment effects in observational studies characterized by unknown (and likely unbalanced) designs and complex dependency structures among…

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