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In a variety of biological processes, eukaryotic cells use cilia to transport flow. Although cilia have a remarkably conserved internal molecular structure, experimental observations report very diverse kinematics. To address this…

Biological Physics · Physics 2012-07-19 Christophe Eloy , Eric Lauga

Microscale fluid flows generated by ensembles of beating eukaryotic flagella are crucial to fundamental processes such as development, motility and sensing. Despite significant experimental and theoretical progress, the underlying physical…

Soft Condensed Matter · Physics 2014-03-11 Douglas R. Brumley , Kirsty Y. Wan , Marco Polin , Raymond E. Goldstein

Systems of active particles can show a large variety of collective behavior. In theory, two aspects determine the collective behavior: the model at the particle level and the parameter regime. While many studies consider a single model and…

Soft Condensed Matter · Physics 2025-11-17 Colin-Marius Koch , Michael Wilczek

Cilia and flagella are hair-like appendages that protrude from the surface of a variety of eukaryotic cells and deform in a wavelike fashion to transport fluids and propel cells. Motivated by the ubiquity of non-Newtonian fluids in biology,…

Fluid Dynamics · Physics 2014-03-19 J. Rodrigo Vélez-Cordero , Eric Lauga

We introduce a measure for energetic efficiency of biological cilia acting individually or collectively and numerically determine the optimal beating patterns according to this criterion. Maximizing the efficiency of a single cilium leads…

Biological Physics · Physics 2011-09-21 Natan Osterman , Andrej Vilfan

Synchronization of actively oscillating organelles such as cilia and flagella facilitates self-propulsion of cells and pumping fluid in low Reynolds number environments. To understand the key mechanism behind synchronization induced by…

Soft Condensed Matter · Physics 2015-05-20 Nariya Uchida , Ramin Golestanian

The modeling of the beating of cilia and flagella in fluids is a particularly active field of study, given the biological relevance of these organelles. Various mathematical models have been proposed to represent the nonlinear dynamics of…

Soft Condensed Matter · Physics 2024-12-10 Irene Anello , François Alouges , Antonio De Simone

Eukaryotes swim with coordinated flagellar (ciliary) beating and steer by fine-tuning the coordination. The model organism for studying flagellate motility, C. reinhardtii (CR), employs synchronous, breast-stroke-like flagellar beating to…

Biological Physics · Physics 2024-06-12 Da Wei , Greta Quaranta , Marie-Eve Aubin-Tam , Daniel S. W. Tam

By taking into account the hydrodynamic interactions in a one dimensional array of model cilia attached to a no-slip cylinderical surface, we investigate their synchronized motion. We show, how does the emergence of metachronal waves depend…

Biological Physics · Physics 2017-05-31 Aref Ghorbani , Ali Najafi

We present a mathematical model of lophotrichous bacteria, motivated by Pseudomonas putida, which swim through fluid by rotating a cluster of multiple flagella extended from near one pole of the cell body. Although the flagella rotate…

Quantitative Methods · Quantitative Biology 2024-08-26 Jeungeun Park , Yongsam Kim , Wanho Lee , Veronika Pfeifer , Valeriia Muraveva , Carsten Beta , Sookkyung Lim

Biological cells are able to generate intricate structures and respond to external stimuli, sculpting their membrane from within. Simplified biomimetic systems can aid in understanding the principles which govern these shape changes and…

The eukaryotic flagellum beats periodically, driven by the oscillatory dynamics of molecular motors, to propel cells and pump fluids. Small, but perceivable fluctuations in the beat of individual flagella have physiological implications for…

Cell Behavior · Quantitative Biology 2015-06-18 Rui Ma , Gary S. Klindt , Ingmar H. Riedel-Kruse , Frank Jülicher , Benjamin M. Friedrich

Biological membranes are host to proteins and molecules which may form domain-like structures resulting in spatially-varying material properties. Vesicles with such heterogeneous membranes can exhibit intricate shapes at equilibrium and…

Soft Condensed Matter · Physics 2023-06-22 Prerna Gera , David Salac , Saverio E. Spagnolie

Interactions between microorganisms and solid boundaries play an important role in biological processes, like egg fertilisation, biofilm formation and soil colonisation, where microswimmers move within a structured environment. Despite…

Biological Physics · Physics 2015-12-23 Matteo Contino , Enkeleida Lushi , Idan Tuval , Vasily Kantsler , Marco Polin

In processes such as embryo shaping, wound healing, and malignant cell invasion, epithelial cells transition between dispersed phases, where the cells move independently, and condensed phases, where they aggregate and deform to close gaps,…

Soft Condensed Matter · Physics 2024-09-25 Anshuman Pasupalak , Zeng Wu , Massimo Pica Ciamarra

The hydrodynamic interactions among bacterial cell bodies, flagella, and surrounding boundaries are essential for understanding bacterial motility in complex environments. In this study, we demonstrate that each slender flagellum can be…

Soft Condensed Matter · Physics 2025-01-07 Baopi Liu , Lu Chen , Ji Zhang

Recent research has shown that motile cells can adapt their mode of propulsion to the mechanical properties of the environment in which they find themselves--crawling in some environments while swimming in others. The latter can involve…

Biological Physics · Physics 2018-05-24 Hao Wu , Marco Avila Ponce de Leon , Hans G. Othmer

Using multiparticle collision dynamics simulations, we investigate the swimming dynamics, orientational behavior, and hydrodynamic interactions of a model swimmer designed to mimic the isolated flagellar apparatus ($FA$) of Chlamydomonas…

Biological Physics · Physics 2025-07-01 Sai Venkata Ramana Ambadipudi , Albert Bae , Azam Gholami

The intricate wobbling motion of flagellated bacteria, characterized by the periodic precession of the cell body, is a determinant factor in their motility and navigation within complex fluid environments. While well-studied in quiescent…

Soft Condensed Matter · Physics 2026-01-26 Wei Feng , Fanglong Dang , Hao Luo , Alan C. H. Tsang , Yanan Liu , Guangyin Jing

Coordinated cilia are used throughout the natural world for micronscale fluid transport. They are often modelled with regular filament arrays on fixed, planar surfaces. Here, we simulate hundreds of interacting active filaments on spherical…

Fluid Dynamics · Physics 2021-12-01 Timothy A Westwood , Eric E Keaveny
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