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Accurate and robust cell nuclei classification is the cornerstone for a wider range of tasks in digital and Computational Pathology. However, most machine learning systems require extensive labeling from expert pathologists for each…

Quantitative Methods · Quantitative Biology 2016-12-05 Stefan Bauer , Nicolas Carion , Peter Schüffler , Thomas Fuchs , Peter Wild , Joachim M. Buhmann

Many real-world applications involve data from multiple modalities and thus exhibit the view heterogeneity. For example, user modeling on social media might leverage both the topology of the underlying social network and the content of the…

Machine Learning · Computer Science 2021-02-16 Lecheng Zheng , Yu Cheng , Hongxia Yang , Nan Cao , Jingrui He

Modern histopathological image analysis relies on the segmentation of cell structures to derive quantitative metrics required in biomedical research and clinical diagnostics. State-of-the-art deep learning approaches predominantly apply…

Image and Video Processing · Electrical Eng. & Systems 2022-01-12 Yoav Alon , Huiyu Zhou

Deep learning models have had a great success in disease classifications using large data pools of skin cancer images or lung X-rays. However, data scarcity has been the roadblock of applying deep learning models directly on prostate…

Computer Vision and Pattern Recognition · Computer Science 2021-01-27 Weiwei Zong , Joon Lee , Chang Liu , Eric Carver , Aharon Feldman , Branislava Janic , Mohamed Elshaikh , Milan Pantelic , David Hearshen , Indrin Chetty , Benjamin Movsas , Ning Wen

Convolutional Neural Networks have achieved impressive results in various tasks, but interpreting the internal mechanism is a challenging problem. To tackle this problem, we exploit a multi-channel attention mechanism in feature space. Our…

Computer Vision and Pattern Recognition · Computer Science 2019-05-22 Masanari Kimura , Masayuki Tanaka

Despite their black-box nature, deep learning models are extensively used in image-based drug discovery to extract feature vectors from single cells in microscopy images. To better understand how these networks perform representation…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Vivek Gopalakrishnan , Jingzhe Ma , Zhiyong Xie

The rapid spread of COVID-19 has necessitated efficient and accurate diagnostic methods. Computed Tomography (CT) scan images have emerged as a valuable tool for detecting the disease. In this article, we present a novel deep learning…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Susmita Ghosh , Abhiroop Chatterjee

We consider the problem of visually explaining similarity models, i.e., explaining why a model predicts two images to be similar in addition to producing a scalar score. While much recent work in visual model interpretability has focused on…

Computer Vision and Pattern Recognition · Computer Science 2020-10-15 Meng Zheng , Srikrishna Karanam , Terrence Chen , Richard J. Radke , Ziyan Wu

Adopting Convolutional Neural Networks (CNNs) in the daily routine of primary diagnosis requires not only near-perfect precision, but also a sufficient degree of generalization to data acquisition shifts and transparency. Existing CNN…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Mara Graziani , Sebastian Otalora , Stephane Marchand-Maillet , Henning Muller , Vincent Andrearczyk

Deep learning has significantly advanced electrocardiogram (ECG) analysis, enabling automatic annotation, disease screening, and prognosis beyond traditional clinical capabilities. However, understanding these models remains a challenge,…

Machine Learning · Computer Science 2025-09-19 Ahcène Boubekki , Konstantinos Patlatzoglou , Joseph Barker , Fu Siong Ng , Antônio H. Ribeiro

We developed a transparent computational large-scale imaging-based framework that can distinguish between normal and metastasizing human cells. The method relies on fluorescence microscopy images showing the spatial organization of actin…

Image and Video Processing · Electrical Eng. & Systems 2024-09-04 Michail Mamalakis , Sarah C. Macfarlane , Scott V. Notley , Annica K. B Gad , George Panoutsos

In recent years, various applications in computer vision have achieved substantial progress based on deep learning, which has been widely used for image fusion and shown to achieve adequate performance. However, suffering from limited…

Computer Vision and Pattern Recognition · Computer Science 2022-08-16 Zhengwen Shen , Jun Wang , Zaiyu Pan , Yulian Li , Jiangyu Wang

Breast cancer remains a leading cause of cancer-related mortality among women worldwide. Ultrasound imaging, widely used due to its safety and cost-effectiveness, plays a key role in early detection, especially in patients with dense breast…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Mohammad Abbadi , Yassine Himeur , Shadi Atalla , Wathiq Mansoor

Automated cervical nucleus segmentation based on deep learning can effectively improve the quantitative analysis of cervical cancer. However, accurate nuclei segmentation is still challenging. The classic U-net has not achieved satisfactory…

Image and Video Processing · Electrical Eng. & Systems 2019-11-13 Jie Zhao , Lei Dai , Mo Zhang , Fei Yu , Meng Li , Hongfeng Li , Wenjia Wang , Li Zhang

Mechanistic interpretability is concerned with analyzing individual components in a (convolutional) neural network (CNN) and how they form larger circuits representing decision mechanisms. These investigations are challenging since CNNs…

Computer Vision and Pattern Recognition · Computer Science 2025-04-18 Robin Hesse , Jonas Fischer , Simone Schaub-Meyer , Stefan Roth

Attention mechanisms form a core component of several successful deep learning architectures, and are based on one key idea: ''The output depends only on a small (but unknown) segment of the input.'' In several practical applications like…

Machine Learning · Computer Science 2023-05-16 Lakshmi Narayan Pandey , Rahul Vashisht , Harish G. Ramaswamy

Deep representation learning is a crucial procedure in multimedia analysis and attracts increasing attention. Most of the popular techniques rely on convolutional neural network and require a large amount of labeled data in the training…

Computer Vision and Pattern Recognition · Computer Science 2020-09-14 Jinghua Wang , Adrian Hilton , Jianmin Jiang

This paper explores interpretability techniques for two of the most successful learning algorithms in medical decision-making literature: deep neural networks and random forests. We applied these algorithms in a real-world medical dataset…

Machine Learning · Computer Science 2020-02-24 Catarina Moreira , Renuka Sindhgatta , Chun Ouyang , Peter Bruza , Andreas Wichert

Breast cancer is the most diagnosed cancer and the most predominant cause of death in women worldwide. Imaging techniques such as the breast cancer pathology helps in the diagnosis and monitoring of the disease. However identification of…

Image and Video Processing · Electrical Eng. & Systems 2019-08-06 Francisco Perdigon Romero , An Tang , Samuel Kadoury

Image segmentation is a key topic in image processing and computer vision with applications such as scene understanding, medical image analysis, robotic perception, video surveillance, augmented reality, and image compression, among many…

Computer Vision and Pattern Recognition · Computer Science 2020-11-17 Shervin Minaee , Yuri Boykov , Fatih Porikli , Antonio Plaza , Nasser Kehtarnavaz , Demetri Terzopoulos