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Speech disorders often occur at the early stage of Parkinson's disease (PD). The speech impairments could be indicators of the disorder for early diagnosis, while motor symptoms are not obvious. In this study, we constructed a new speech…

Audio and Speech Processing · Electrical Eng. & Systems 2021-06-01 Hao Fang , Chen Gong , Chen Zhang , Yanan Sui , Luming Li

Parkinson's disease (PD) is a chronic neurodegenerative disease. Early diagnosis is essential to mitigate the progressive deterioration of patients' quality of life. The most characteristic motor symptoms are very mild in the early stages,…

Machine Learning · Computer Science 2026-01-27 Beatriz Pérez-Sánchez , Noelia Sánchez-Maroño , Miguel A. Díaz-Freire

Parkinsons disease is the second most prevalent neurodegenerative disorder with over ten million active cases worldwide and one million new diagnoses per year. Detecting and subsequently diagnosing the disease is challenging because of…

Computation and Language · Computer Science 2024-04-09 Jonathan Crawford

To extract robust deep representations from long sequential modeling of speech data, we propose a self-supervised learning approach, namely Contrastive Separative Coding (CSC). Our key finding is to learn such representations by separating…

Audio and Speech Processing · Electrical Eng. & Systems 2021-03-02 Jun Wang , Max W. Y. Lam , Dan Su , Dong Yu

Speech impairments are prevalent biomarkers for Parkinson's Disease (PD), motivating the development of diagnostic techniques using speech data for clinical applications. Although deep acoustic features have shown promise for PD…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-01 Emmy Postma , Cristian Tejedor-Garcia

This paper proposes a novel unsupervised autoregressive neural model for learning generic speech representations. In contrast to other speech representation learning methods that aim to remove noise or speaker variabilities, ours is…

Computation and Language · Computer Science 2019-06-20 Yu-An Chung , Wei-Ning Hsu , Hao Tang , James Glass

Changes in speech and language are among the first signs of Parkinson's disease (PD). Thus, clinicians have tried to identify individuals with PD from their voices for years. Doctors can leverage AI-based speech assessments to spot PD…

Sound · Computer Science 2023-12-06 Mahboobeh Parsapoor

Speech signals are inherently complex as they encompass both global acoustic characteristics and local semantic information. However, in the task of target speech extraction, certain elements of global and local semantic information in the…

Sound · Computer Science 2024-08-27 Zhaoxi Mu , Xinyu Yang , Sining Sun , Qing Yang

Parkinson's Disease (PD) affects over 10 million people globally, with speech impairments often preceding motor symptoms by years, making speech a valuable modality for early, non-invasive detection. While recent deep-learning models…

Sound · Computer Science 2025-08-29 Terry Yi Zhong , Cristian Tejedor-Garcia , Martha Larson , Bastiaan R. Bloem

The potential of deep learning in clinical speech processing is immense, yet the hurdles of limited and imbalanced clinical data samples loom large. This article addresses these challenges by showcasing the utilization of automatic speech…

This paper represents a groundbreaking advancement in Parkinson disease (PD) research by employing a novel machine learning framework to categorize PD into distinct subtypes and predict its progression. Utilizing a comprehensive dataset…

Machine Learning · Computer Science 2024-06-12 Ashwin Ram

Unsupervised representation learning for speech processing has matured greatly in the last few years. Work in computer vision and natural language processing has paved the way, but speech data offers unique challenges. As a result, methods…

Audio and Speech Processing · Electrical Eng. & Systems 2022-03-04 Lasse Borgholt , Jakob Drachmann Havtorn , Joakim Edin , Lars Maaløe , Christian Igel

Parkinson's disease (PD) is a progressive degenerative disorder of the central nervous system characterized by motor and non-motor symptoms. As the disease progresses, patients alternate periods in which motor symptoms are mitigated due to…

Audio and Speech Processing · Electrical Eng. & Systems 2020-08-26 Anna Pompili , Rubén Solera-Ureña , Alberto Abad , Rita Cardoso , Isabel Guimarães , Margherita Fabbri , Isabel P. Martins , Joaquim Ferreira

Self-supervised speech representations have been shown to be effective in a variety of speech applications. However, existing representation learning methods generally rely on the autoregressive model and/or observed global dependencies…

Computation and Language · Computer Science 2020-11-03 Alexander H. Liu , Yu-An Chung , James Glass

The potential of speech as a non-invasive biomarker to assess a speaker's health has been repeatedly supported by the results of multiple works, for both physical and psychological conditions. Traditional systems for speech-based disease…

Audio and Speech Processing · Electrical Eng. & Systems 2020-06-02 Catarina Botelho , Francisco Teixeira , Thomas Rolland , Alberto Abad , Isabel Trancoso

There are individual differences in expressive behaviors driven by cultural norms and personality. This between-person variation can result in reduced emotion recognition performance. Therefore, personalization is an important step in…

Audio and Speech Processing · Electrical Eng. & Systems 2023-09-06 Minh Tran , Yufeng Yin , Mohammad Soleymani

Using speech samples as a biomarker is a promising avenue for detecting and monitoring the progression of Parkinson's disease (PD), but there is considerable disagreement in the literature about how best to collect and analyze such data.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-07-24 Peter Plantinga , Briac Cordelle , Dominique Louër , Mirco Ravanelli , Denise Klein

Neural network-based anomaly detection remains challenging in clinical applications with little or no supervised information and subtle anomalies such as hardly visible brain lesions. Among unsupervised methods, patch-based auto-encoders…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Nicolas Pinon , Geoffroy Oudoumanessah , Robin Trombetta , Michel Dojat , Florence Forbes , Carole Lartizien

One of the symptoms observed in the early stages of Parkinson's Disease (PD) is speech impairment. Speech disorders can be used to detect this disease before it degenerates. This work analyzes speech features and machine learning approaches…

Audio and Speech Processing · Electrical Eng. & Systems 2021-11-22 Adedolapo Aishat Toye , Suryaprakash Kompalli

Labeled speech data from patients with Parkinsons disease (PD) are scarce, and the statistical distributions of training and test data differ significantly in the existing datasets. To solve these problems, dimensional reduction and sample…

Machine Learning · Computer Science 2020-02-11 Xiaoheng Zhang , Yongming Li , Pin Wang , Xiaoheng Tan , Yuchuan Liu