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Automated in-vitro cell detection and counting have been a key theme for artificial and intelligent biological analysis such as biopsy, drug analysis and decease diagnosis. Along with the rapid development of microfluidics and lab-on-chip…

Computer Vision and Pattern Recognition · Computer Science 2020-01-08 Tiancheng Xia , Richard Jiang , YongQing Fu , Nanlin Jin

Hematological disorders, which involve a variety of malignant conditions and genetic diseases affecting blood formation, present significant diagnostic challenges. One such major challenge in clinical settings is differentiating…

Image and Video Processing · Electrical Eng. & Systems 2024-11-27 Buddhadev Goswami , Adithya B. Somaraj , Prantar Chakrabarti , Ravindra Gudi , Nirmal Punjabi

Objectives To develop and validate a deep learning-based diagnostic model incorporating uncertainty estimation so as to facilitate radiologists in the preoperative differentiation of the pathological subtypes of renal cell carcinoma (RCC)…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Ni Yao , Hang Hu , Kaicong Chen , Chen Zhao , Yuan Guo , Boya Li , Jiaofen Nan , Yanting Li , Chuang Han , Fubao Zhu , Weihua Zhou , Li Tian

White blood cell (WBC) classification is fundamental for hematology applications such as infection assessment, leukemia screening, and treatment monitoring. However, real-world WBC datasets present substantial appearance variations caused…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Luu Le , Hoang-Loc Cao , Ha-Hieu Pham , Thanh-Huy Nguyen , Ulas Bagci

Timely and affordable computer-aided diagnosis of retinal diseases is pivotal in precluding blindness. Accurate retinal vessel segmentation plays an important role in disease progression and diagnosis of such vision-threatening diseases. To…

Image and Video Processing · Electrical Eng. & Systems 2023-04-26 Tariq M. Khan , Syed S. Naqvi , Antonio Robles-Kelly , Imran Razzak

Deep learning based approaches to Computer Aided Diagnosis (CAD) typically pose the problem as an image classification (Normal or Abnormal) problem. These systems achieve high to very high accuracy in specific disease detection for which…

Computer Vision and Pattern Recognition · Computer Science 2020-10-06 Aniket Joshi , Gaurav Mishra , Jayanthi Sivaswamy

Recognizing the types of white blood cells (WBCs) in microscopic images of human blood smears is a fundamental task in the fields of pathology and hematology. Although previous studies have made significant contributions to the development…

Image and Video Processing · Electrical Eng. & Systems 2023-05-22 Satoshi Tsutsui , Zhengyang Su , Bihan Wen

Despite fluorescent cell-labelling being widely employed in biomedical studies, some of its drawbacks are inevitable, with unsuitable fluorescent probes or probes inducing a functional change being the main limitations. Consequently, the…

Quantitative Methods · Quantitative Biology 2020-03-03 Yan Ge , Philipp Rosendahl , Claudio Durán , Nicole Töpfner , Sara Ciucci , Jochen Guck , Carlo Vittorio Cannistraci

Diagnosis of hematological malignancies depends on accurate identification of white blood cells in peripheral blood smears. Deep learning techniques are emerging as a viable solution to scale and optimize this process by automatic cell…

Computer Vision and Pattern Recognition · Computer Science 2024-08-01 Michael Deutges , Ario Sadafi , Nassir Navab , Carsten Marr

Computer-aided methods for analyzing white blood cells (WBC) have become widely popular due to the complexity of the manual process. Recent works have shown highly accurate segmentation and detection of white blood cells from microscopic…

Image and Video Processing · Electrical Eng. & Systems 2019-10-03 Changhun Jung , Mohammed Abuhamad , Jumabek Alikhanov , Aziz Mohaisen , Kyungja Han , DaeHun Nyang

The objective of the study is to evaluate the efficiency of a multi layer neural network models built by combining Recurrent Neural Network(RNN) and Convolutional Neural Network(CNN) for solving the problem of classifying different types of…

Computer Vision and Pattern Recognition · Computer Science 2021-01-12 Indraneel Ghosh , Siddhant Kundu

Automatic analysis of retinal blood images is of vital importance in diagnosis tasks of retinopathy. Segmenting vessels accurately is a fundamental step in analysing retinal images. However, it is usually difficult due to various imaging…

Computer Vision and Pattern Recognition · Computer Science 2019-02-12 Yishuo Zhang , Albert C. S. Chung

Supervised deep learning algorithms have enabled significant performance gains in medical image classification tasks. But these methods rely on large labeled datasets that require resource-intensive expert annotation. Semi-supervised…

Identifying and characterizing the patient's blood samples is indispensable in diagnostics of malignance suspicious. A painstaking and sometimes subjective task is used in laboratories to manually classify white blood cells. Neural…

Image and Video Processing · Electrical Eng. & Systems 2020-10-23 Daouda Diouf , Djibril Seck , Mountaga Diop , Abdoulye Ba

Motivated by the numerous healthcare applications of molecular communication within Internet of Bio-Nano Things (IoBNT), this work addresses the problem of abnormality detection in a blood vessel using multiple biological embedded computing…

Information Theory · Computer Science 2018-07-10 Neeraj Varshney , Adarsh Patel , Yansha Deng , Werner Haselmayr , Pramod K. Varshney , Arumugam Nallanathan

This study presents an approach to developing a model for classifying abnormalities in video capsule endoscopy (VCE) frames. Given the challenges of data imbalance, we implemented a tiered augmentation strategy using the albumentations…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Aakarsh Bansal , Bhuvanesh Singla , Raajan Rajesh Wankhade , Nagamma Patil

Within (semi-)automated visual inspection, learning-based approaches for assessing visual defects, including deep neural networks, enable the processing of otherwise small defect patterns in pixel size on high-resolution imagery. The…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 André Luiz B. Vieira e Silva , Francisco Simões , Danny Kowerko , Tobias Schlosser , Felipe Battisti , Veronica Teichrieb

Anomaly detection is defined as the problem of finding data points that do not follow the patterns of the majority. Among the various proposed methods for solving this problem, classification-based methods, including one-class Support…

Optimization and Control · Mathematics 2023-12-05 Amir Hossein Noormohammadia , Seyed Ali MirHassania , Farnaz Hooshmand Khaligh

Accurately classifying white blood cells from microscopic images is essential to identify several illnesses and conditions in medical diagnostics. Many deep learning technologies are being employed to quickly and automatically classify…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Tatwadarshi P. Nagarhalli , Shruti S. Pawar , Soham A. Dahanukar , Uday Aswalekar , Ashwini M. Save , Sanket D. Patil

Diabetic Macular Edema (DME), a prevalent complication among diabetic patients, constitutes a major cause of visual impairment and blindness. Although deep learning has achieved remarkable progress in medical image analysis, traditional DME…

Image and Video Processing · Electrical Eng. & Systems 2025-03-10 Wei Yang , Yiran Zhu , Jiayu Shen , Yuhan Tang , Chengchang Pan , Hui He , Yan Su , Honggang Qi